supported by the National Key R&D Program of China(2022YFC3500300);the National Natural Science Foundation of China(82130109,81973499);the CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-I2M-1-020).
Emerging evidence shows that psychological stress promotes the progression of Parkinson’s disease(PD)and the onset of dyskinesia in non-PD individuals,highlighting a potential avenue for therapeutic intervention.We p...
supported by the Scientific Research Project of the Traditional Chinese Medicine Bureau of Guangdong Province(Nos.20203002,20211188,and 20222082);the Special Funding for TCM Science and Technology Reasearch of Guangdong Provincial Hospital of Chinese Medicine(No.CMR-2017022-1001).
Amyotrophic lateral sclerosis(ALS)is a fatal neurodegenerative disease affecting both upper and lower motor neurons in the brain and spinal cord.One important aspect of ALS pathogenesis is superoxide dismutase 1(SOD1)...
supported by grants from National Natural Science Foundation of China(82122009,82170605,81873573 and 81970515);Guangdong Natural Science Funds for Distinguished Young Scholar(2019B151502013,China)。
Chronic alcohol consumption causes liver steatosis,cell death,and inflammation.Melatonin(MLT)is reported to alleviate alcoholic liver disease(ALD)-induced injury.However,its direct regulating targets in hepatocytes ar...
为探究重组大肠埃希菌不耐热肠毒素B亚单位(B subunit of heat-labile enterotoxin,LTB)和人参皂苷Rg1联合滴鼻免疫小鼠的佐剂效果并评估其生物安全性,本研究分别将生理盐水,猪繁殖与呼吸综合征病毒(porcine reproductive and respirato...
This work was supported by the National Natural Science Foundation of China(81973499,81873026,81730096,82074044,81773924,and 81960729);the CAMS Innovation Fund for Medical Sciences(CIFMS)(2016-I2M-1-004);the Opening Program of the Shanxi Key Laboratory of Chinese Medicine Encephalopathy(CME-OP-2017001);the High-End Foreign Experts Introduction Program(G20200001485).
Myelin damage and abnormal remyelination processes lead to central nervous system dysfunction.Glial activation-induced microenvironment changes are characteristic features of the diseases with myelin abnormalities.We ...