RIBONUCLEASE

作品数：31被引量：61H指数：5
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相关领域：医药卫生生物学更多>>
相关作者：王鹏信丰学钟盛华祁庆生许先进更多>>
相关机构：中国农业大学清华大学华中农业大学江西农业大学更多>>
相关期刊：《mLife》《Agricultural Sciences》《生物工程学报》《Asian Journal of Andrology》更多>>
相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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A novel loss-of-function variant in PNLDC1 inducing oligo-astheno-teratozoospermia and male infertility
《Asian Journal of Andrology》2023年第5期643-645,共3页Si-Yi Zhao Lan-Lan Meng Zhao-Li Du Yue-Qiu Tan Wen-Bin He Xiong Wang 
supported by grants from the National Key Research and Development Program of China(2022YFC2702604);the National Natural Science Foundation of China(82171608,82201773,and 81971447);the China Postdoctoral Science Foundation(2022M711119);the Scientific Research Foundation of the Health Committee of Hunan Province(B202301039323 and B202301039518).
Male infertility is a major reproductive disorder,which is clinically characterized by highly heterogeneous phenotypes of abnormal sperm count or quality.To date,five male patients with biallelic loss-of-function(LOF)...
关键词：loss-of-function variant male infertility oligo-astheno-teratozoospermia PARN-like ribonuclease domain-containing exonuclease 1 
Poly(A)-specific ribonuclease protein promotes the proliferation,invasion and migration of esophageal cancer cells
《World Journal of Gastroenterology》2023年第31期4783-4796,共14页Fu-Wei Zhang Xiao-Wei Xie Meng-Hua Chen Jian Tong Qun-Qing Chen Jing Feng Feng-Ti Chen Wen-Qi Liu 
BACKGROUND Bioinformatics analysis showed that the expression of the poly(A)-specific ribonuclease(PARN)gene in gastric cancer,head and neck squamous cell carcinoma,melanoma,cervical cancer and lung squamous cell carc...
关键词：Poly(A)-specific ribonuclease Esophageal cancer APOPTOTIC Phosphatidylinositol 3-kinase/protein kinase B 
Birth-and-death evolution of ribonuclease 9 genes in Cetartiodactyla被引量：2
《Science China(Life Sciences)》2023年第5期1170-1182,共13页Datian Lang Xiaoping Wang Chunbing Liu Weihang Geng David M.Irwin Shanyuan Chen Chunqing Li Li Yu Heng Xiao 
supported by the Special Basic Cooperative Research Programs of Yunnan Provincial Undergraduate Universities(202001AO070195);the National Natural Science Foundation of China(31925006);the Applied Basic Research General Project of Yunnan Science Technology Department(202001BB050058)。
RNase9 plays a reproductive function and has been recognized as an important member of the ribonuclease(RNase)A superfamily,a gene family that is widely used as a model for molecular evolutionary studies.Here,we ident...
关键词：RNase9 gene duplication gene loss CETARTIODACTYLA 
Regulation of RNase E during the UV stress response in the cyanobacterium Synechocystis sp.PCC 6803
《mLife》2023年第1期43-57,共15页Satoru Watanabe Damir Stazic Jens Georg Shota Ohtake Yutaka Sakamaki Megumi Numakura Munehiko Asayama Taku Chibazakura Annegret Wilde Claudia Steglich Wolfgang R.Hess 
supported by Grants-in-Aid 25850056,S2306,and 20K05793 from the Ministry of Education,Culture,Sports,Science and Technology of Japan,the Advanced Low Carbon Technology Research and Development Program(ALCA)of the Japan Science and Technology Agency(JST)(to S.W.);the German Ministry of Education and Research(BMBF),grant no.031L0164B“RNAProNet”(to W.R.H.);the German Science Foundation(DFG)research training group MeInBio 322977937/GRK2344(to A.W.and W.R.H.);grant STE 1119/4-2(to C.S.).
Endoribonucleases govern the maturation and degradation of RNA and are indispensable in the posttranscriptional regulation of gene expression.A key endoribonuclease in Gram-negative bacteria is RNase E.To ensure an ap...
关键词：CYANOBACTERIA protein turnover RIBONUCLEASE stress response 
Expression levels of interferon-α receptor,interferon-stimulated gene factor 3,double-stranded RNA-activated protein kinase and ribonuclease L in chronic hepatitis B patients treated with interferon
《China Medical Abstracts(Internal Medicine)》2021年第1期50-51,共2页YANG Qian 
Objective To investigate the expression levels of interferon-α receptor (IFNAR),interferon-stimulated gene factor 3 (ISGF3),double-stranded RNA-activated protein kinase (PKR) and ribonuclease L (RNase L) in patients ...
关键词：INTERFERON patients Nanchang 
Fg12 ribonuclease secretion contributes to Fusarium graminearum virulence and induces plant cell death被引量：3
《Journal of Integrative Plant Biology》2021年第2期365-377,共13页Bo Yang Yuyin Wang Mengjun Tian Kaixin Dai Wenyue Zheng Zehan Liu Sen Yang Xinyu Liu Dongya Shi Haifeng Zhang Yan Wang Wenwu Ye Yuanchao Wang 
supported by the National Natural Science Foundation of China (31721004);the National Postdoctoral Program for Innovative Talents (BX20180142);the China Postdoctoral Science Foundation (2018M640496);the Natural Science Foundation of Jiangsu Province (BK20190520);the Fundamental Research Funds for the Central Universities (KYXK202010)。
Filamentous fungal pathogens secrete effectors that modulate host immunity and facilitate infection. Fusarium graminearum is an important plant pathogen responsible for various devastating diseases. However, little is...
关键词：cell death EFFECTOR fungal ribonuclease Fusarium graminearum VIRULENCE 
Role of Pathogen-Related Protein 10 (PR 10) under Abiotic and Biotic Stresses in Plants被引量：1
《Phyton-International Journal of Experimental Botany》2020年第2期167-182,共16页Rakesh Kumar Sinha Shiv Shankar Verma Anshu Rastogi 
The work supported by the grant Ministry of Education of the Czech Republic with co-financing from the European Union(grant“KOROLID”,CZ.02.1.01/0.0/0.0/15_003/0000336);the Czech Academy of Sciences(RVO:60077344).
Members of the Pathogenesis Related(PR)10 protein family have been identified in a variety of plant species and a wide range of functions ranging from defense to growth and development has been attributed to them.PR10...
关键词：Pathogenesis-related(PR) PR10 abiotic stress biotic stress RIBONUCLEASE stress tolerance nitric oxide 
Angiogenin and tRNA fragments in Parkinson’s disease and neurodegeneration被引量：6
《Acta Pharmacologica Sinica》2020年第4期442-446,共5页Jochen H M Prehn Elisabeth Jirstrom 
supported in part by a research grant from Science Foundation Ireland(SFI)under Grant Number 16/RC/3948 and cofunded under the European Regional Development Fund and by FutureNeuro industry partners and by the Joint Programme in Neurodegeneration Research(JPND)project RNA-NEURO supported by SFI(17/JPND/3455).
In this review,we summarise the evidence for a role of the ribonuclease angiogenin in the pathophysiology of neurodegenerative disorders,with a specific focus on Parkinson’s disease(PD).Angiogenin is a stress-induced...
关键词：ANGIOGENIN RIBONUCLEASE RIBOSOMAL RNA(rRNA) transfer RNA(tRNA) tRNA-derived fragments(tRFs) neuroprotection 
Adaptive evolutionary expansion of the ribonuclease 6 in Rodentia被引量：1
《Integrative Zoology》2019年第3期306-317,共12页Datian LANG Burton KLIM Yun GAO Xiaoping WANG 
the Yunnan Applied Ba­sic Research Project(2017FD148);the State Key Basic Research and Development Plan in Kunming In­stitute of Zoology(GREKF17-02,to DTL);the Na­tional Natural Science Foundation of China(31760619,to XPW).
Ribonuclease 6(RNase6 or RNase K6)is a protein that belongs to a superfamily thought to be the sole verte­brate-specific enzyme known for a wide range of physiological functions,including digestion,cytotoxicity,an­gio...
关键词：gene duplication gene sorting pancreatic ribonuclease 6(RNase6) positive selection RODENTIA 
Structural insights into the CRISPR-Cas-associated ribonuclease activity of Staphylococcus epidermidis Csm3 and Csm6被引量：1
《Science Bulletin》2018年第11期691-699,共9页Yanqun Zhao Jinjing Wang Qiu Sun Chao Dou Yijun Gu Chunlai Nie Xiaofeng Zhu Yuquan Wei Wei Cheng 
supported by the National Natural Science Foundation of China(31570842 to W.C.);the National Young Thousand Talents Program;the Sichuan Province Thousand Talents Program in China
The Clustered Regularly Interspaced Short _Palindromic Repeats （CRISPR）-CRISPR-associated （Cas） system is an adaptive immune system in bacteria and archaea that resists exogenous invasion through nucleic acid-medi...
关键词：CRISPR-Cas Csm3 Csm6 Ribonuclease Staphylococcus epidermidis 
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