supported by the National Institutes of Health(K99-R00AG049958 and S10OD028493);the American Heart Association(24POST1188725);the Heritage Medical Foundation,the Wu Tsai Human Performance Alliance,the Arthritis National Research Foundation,and the American Federation for Aging Research.
Skeletal stem cells(SSCs)are crucial for skeletal development and regeneration,yet the epigenetic regulation of these cells remains poorly understood.Recent studies have delineated the epigenetic landscape across the ...
supported by the National Key Research and Development Program of China(2022YFA0103200);the National Natural Science Foundation of China(82325003,82230007,82200188,82270956 and 82171568);the National Defense Biotechnology Outstanding Young Talents Fund(01-SWKJYCJJ24);Shaanxi Province Innovation Capability Support Program Scientific and Technological Innovation Team(2023-CX-TD-69).
Stem cells remain in a quiescent state for long-term maintenance and preservation of potency;this process requires fine-tuning regulatory mechanisms.In this study,we identified the epigenetic landscape along the devel...
The mechanism of skeletal reorganization of1,6-enynes catalyzed by GaCl3 has been studied with the density functional method at the B3LYP/6-31G* level. Thestructures and energies of the stationary points were calcu-la...
A 22-mer peptide, identical to the primary sequence of domain I segment 4 (IS4) of rat brain sodium channel I, has been synthesized. IS4 peptide can incorporate into cultured rat skeletal myotube membranes and form io...
Whether there is isotope fractionation caused by metabolism (vital effect) of bra-chiopods in geologic time with their shells’ δ18O and δ13C has been studied intensively in the field of carbonate isotope geochemist...
Ⅰ. INTRODUCTION The survival of motoneurons in vertebrates during their embryonic period depends on certain neurotrophic substances provided from their skeletal muscles. Skeletal muscles have been shown, in in vitro ...
Project supported by the National High Technology Development Program (863-102-18-49).
Dystrophin is the first identified human huge protein by the approach of reverse genetics. The molecular weight of dystrophin is 430 kD. The protein exists mainly on the cell membrane of skeletal muscle, cardiac muscl...
Duchenne muscular dystrophy (DMD) is X-linked muscular disorder, with an incidence of approximately 1 in 3500 newborn males. The patient is characterised by progressive wasting of the skeletal muscles and usually dies...