云南高校图书馆联盟文献共享服务平台- SMEDDS

SMEDDS: 作品数：19被引量：75H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：潘卫三杨荣平王云红葛蔓全东琴更多>>; 相关机构：沈阳药科大学天津中医药大学中国药科大学重庆市中药研究院更多>>; 相关期刊：《新中医》《Asian Journal of Pharmaceutical Sciences》《现代药物与临床》《Journal of Chinese Pharmaceutical Sciences》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划安徽省自然科学基金天津市科技支撑计划重点项目更多>>

Gastrointestinal lipolysis and trans-epithelial transport of SMEDDS via oral route被引量：6: 《Acta Pharmaceutica Sinica B》2021年第4期1010-1020,共11页Fei Xia Zhongjian Chen Quangang Zhu Jianping Qi Xiaochun Dong Weili Zhao Wei Wu Yi Lu; supported by the National Natural Science Foundation of China(Nos.82030107,81973247,81872815,81872826,and 81690263);Science and Technology Commission of Shanghai Municipality(Nos.19XD1400300,19430741400,and 19410761200,China)。; Self-microemulsifying drug delivery systems(SMEDDSs)have recently returned to the limelight of academia and industry due to their enormous potential in oral delivery of biomacromolecules.However,information on gastroi...; 关键词：SMEDDS In vivo fate LIPOLYSIS Trans-epithelial transport LYMPH Aggregation-caused quenching CACO-2 Absorption

Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymphatic uptake被引量：15: 《Acta Pharmaceutica Sinica B》2017年第3期353-360,共8页Fang Li Rongfeng Hu Bin Wang Yun Gui Gang Cheng Song Gao Lei Ye Jihui Tang; supported by the National Natural Science Foundation of China(Grant Nos.81274100;81573615);Natural Science Foundation of Anhui Province of China(Grant No.1408085QH189);Key Project for the Excellent Higher Education of Anhui Province of China(Grant No.2013SQRL019ZD);Research Project for the Science and Technology of Bozhou city of China(Grant No.BK2015005); Huperzine A(Hup-A) is a poorly water-soluble drug with low oral bioavailability. A selfmicroemulsifying drug delivery system(SMEDDS) was used to enhance the oral bioavailability and lymphatic uptake and transport of H...; 关键词：Huperzine A SELF-MICROEMULSION Drug delivery systems SMEDDS BIOAVAILABILITY Single-pass intestinal perfusion Lymphatic transport

Effect of ionization of drug on drug solubilization in SMEDDS prepared using Capmul MCM and caprylic acid被引量：1: 《Asian Journal of Pharmaceutical Sciences》2017年第1期73-82,共10页Suhua Li Parshotam Madan Senshang Lin; St. John’s University for providing financial assistance; The purpose of this study was to investigate the effect of ionization of drug on drug solubilization in SMEDDS(self-microemulsifying drug delivery system) prepared using Capmul MCM and caprylic acid. Solubilization ca...; 关键词：SMEDDS Capmul MCM Caprylic acid IONIZATION INDOMETHACIN HALOPERIDOL

PUBLISHER’S NOTE: 《Asian Journal of Pharmaceutical Sciences》2017年第1期114-114,共1页Shannon Qu; February 2017Elsevier would like to bring to your attention a pagination gap in Volume/Issue 12/1.Unfortunately,there is a pagination gap between article'Effect of ionization of drug on drug solubilization in SMEDDS p...; 关键词：SMEDDS PUBLISHER’S NOTE

Preparation and characterization of solidified SMEDDS containing flurbiprofen by spray drying method: 《Asian Journal of Pharmaceutical Sciences》2016年第1期108-109,共2页Yoo-Jeong Jang Kwan Hyung Cho; Flurbiprofen, a non-steroidal anti-inflammatory agent, is used to treat rheumatoid arthritis and sore throat (1)However, it gave poor water solubility, and various solubilization technique such as self-microemulsifyin...; 关键词：FLURBIPROFEN SOLIDIFIED SMEDDS SOLUBILIZATION

一种全新合成的抗抑郁药物的自微乳化载药系统(SMEDDS)理化性质和体外释药行为研究被引量：3: 《药学研究》2015年第4期215-218,共4页乌兰何伟赵锦花王国成尹莉芳; 国家"十二五""重大新药创制"科技重大专项(No.2013zx09402202);天津市科技支撑计划重点项目(No.12ZCZDSY01200); 目的研究一种全新合成的抗抑郁药物AJS的自微乳化制剂(AJS-SMEDDS)的理化性质和体外释药行为。方法考察AJS-SMEDDS制剂的黏度、zeta电位和粒度,研究其流变学性质及电学性质;采用总体液平衡反向透析法测定其体外释药性能;并考察了其稳定...; 关键词：自微乳化载药系统粒径流体稳定性释放

自微乳化给药系统促进银杏酮酯口服吸收效果实验研究被引量：1: 《新中医》2015年第5期278-279,共2页高文娟; 目的：观察自微乳化给药系统（SMEDDS）对提高银杏酮酯（GBE50）口服吸收效果的影响。方法：将12只SD大鼠随机分为2组各6只,观察组将经自微乳化给药系统处理得到的银杏酮酯口服自微乳灌入大鼠胃中,对照组应用市售杏灵颗粒剂进行灌胃,比...; 关键词：自微乳化给药系统(SMEDDS) 银杏酮酯(GBE50) 口服吸收有效药物浓度生物利用度

Enhancement of solubility and therapeutic potential of poorly soluble lovastatin by SMEDDS formulation adsorbed on directly compressed spray dried magnesium aluminometasilicate liquid loadable tablets: A study in diet induced hyperlipidemic rabbits: 《Asian Journal of Pharmaceutical Sciences》2015年第1期40-56,共17页Mohd Javed Qureshi Chitneni Mallikarjun Wong Gan Kian; International Medical University(IMU),Malaysia for financially supporting the present work under the research grant number BPharm B0108_Res322011.; The aim of present study was to formulate and evaluate a self-microemulsifying drug delivery systems(SMEDDS)containing lovastatin and to further explore the ability of porous Neusilin■ US2 tablet as a solid carrier f...; 关键词：LOVASTATIN Self-microemulsifying drug delivery system(SMEDDS) Neusilin■US2 Liquid loadable tablet Solid carrier system Pharmacodynamics studies

SMEDDS在中药制剂过程中的应用与发展被引量：1: 《中国医药指南》2014年第35期64-65,共2页冮怡琳李鑫; 介绍SMEDDS的研究进展。根据国内、国外文献报道,对SMEDDS的基本特点、研究过程中遇到的问题、SMEDDS技术的优势进行综述。SMEDDS将有广泛的发展前景。; 关键词：自微乳综述优势发展

HPLC同时检测姜黄素-胡椒碱复方自微乳中姜黄素和胡椒碱的含量被引量：6: 《药物分析杂志》2014年第11期1964-1968,共5页李秋萍郗砚彬翟文文蒋俏丽戴俊东; 北京中医药大学复方中药制剂研究创新团队发展计划资助(2011-CXTD-13);北京中医药大学自主选题项目资助(2014-JYBZZ-XS-087); 目的：建立在同一色谱条件下同时检测姜黄素-胡椒碱复方自微乳中姜黄素和胡椒碱含量的HPLC含量测定方法。方法：采用Purospher STAR LP C18色谱柱（4.6 mm×250 mm,5μm）,以乙腈-4%醋酸水溶液（55∶45）为流动相,流速1 mL·min^-1,检...; 关键词：姜黄素胡椒碱复方自微乳药物制剂高效液相色谱方法验证自微乳给药系统(SMEDDS)质量控制

SMEDDS