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Gut virome:New key players in the pathogenesis of inflammatory bowel disease被引量：1: 《World Journal of Methodology》2025年第2期27-43,共17页Helal F Hetta Rehab Ahmed Yasmin N Ramadan Hayam Fathy Mohammed Khorshid Mohamed M Mabrouk Mai Hashem; Inflammatory bowel disease(IBD)is a chronic inflammatory illness of the intes-tine.While the mechanism underlying the pathogenesis of IBD is not fully under-stood,it is believed that a complex combination of host immu...; 关键词：Inflammatory bowel disease PATHOGENESIS Gut virome BACTERIOPHAGE Eukaryotic viruses

The role of axon guidance molecules in the pathogenesis of epilepsy: 《Neural Regeneration Research》2025年第5期1244-1257,共14页Zheng Liu Chunhua Pan Hao Huang; supported by the National Natural Science Foundation of China,Nos. 81760247, 82171450;the Scientific Research Foundation for Doctors of the Affiliated Hospital of Zunyi Medical University,No.(2016)14 (all to HH)。; Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target no...; 关键词：axon guidance drug-resistant epilepsy EPILEPSY nerve regeneration nervous system diseases neural pathways neuroinflammatory diseases neuronal plasticity NEURONS synaptic remodeling

The complex effects of miR-146a in the pathogenesis of Alzheimer's disease: 《Neural Regeneration Research》2025年第5期1309-1323,共15页Yunfan Long Jiajia Liu Yu Wang Haidong Guo Guohong Cui; supported by the National Natural Science Foundation of China,No.81970991(to GC);Program of Shanghai Academic Research Leader,No.22XD1423400(to HG)。; Alzheimer's disease is a neurodegenerative disorder characterized by cognitive dysfunction and behavioral abnormalities.Neuroinflammatory plaques formed through the extracellular deposition of amyloid-βproteins,as we...; 关键词：Alzheimer's disease amyloid-β glial cells MICRORNAS MIR-146A neuroinflammatory

Advances in the pathophysiology and treatment of focal segmental glomerulosclerosis:The importance of a timely and tailored approach: 《World Journal of Nephrology》2025年第2期1-8,共8页Guido Gembillo Concetto Sessa Domenico Santoro; Focal segmental glomerulosclerosis(FSGS)is a histological pattern of glomerular damage that significantly contributes to chronic kidney disease and end-stage renal disease.Its incidence is rising globally,necessitatin...; 关键词：Focal segmental glomerulosclerosis Chronic kidney disease GLOMERULONEPHRITIS Renal failure Immunosuppressive therapy Calcineurin inhibitors Mycophenolate mofetil RITUXIMAB Sparsentan PLASMAPHERESIS

From health literacy to organ donation and transplantation awareness:The path through self-control: 《World Journal of Psychiatry》2025年第4期271-277,共7页Amil Huseynov Begum Satici; BACKGROUND Organ donation and transplantation are vital for saving lives,yet awareness remains limited.Health literacy,the ability to understand and use health information,and self-control,which influences decision-ma...; 关键词：Health literacy Organ donation Organ transplantation Self-assessments MEDIATION

Role of gut microbiota and mesenteric adipose tissue in the pathology of Crohn’s disease:Potential therapeutic targets: 《World Journal of Gastroenterology》2025年第13期1-6,共6页Han-Jung Liu Meng-Che Wu Shuo-Yan Gau; This editorial comments on the article by Wu et al in the World Journal of Gastroenterology.The article explored the relationship between mesenteric adipose tissue,creeping fat,inflammation,and gut microbiota in Crohn...; 关键词：Crohn’s disease Gut microbiota PROBIOTICS Ulcerative colitis Inflammatory bowel disease

Leucine-rich alpha-2 glycoprotein for detecting small bowel lesions in Crohn’s disease:A critical review and the path forward: 《World Journal of Gastrointestinal Endoscopy》2025年第4期74-78,共5页Arunkumar Krishnan; The study by Ohno et al provides valuable insights into the role of leucine-rich alpha-2-glycoprotein(LRG)as a potential biomarker for identifying small bowel lesions in Crohn's disease(CD).However,several methodologi...; 关键词：Crohn's disease Leucine-rich alpha-2 glycoprotein Biomarkers Small bowel lesions Inflammatory bowel disease Disease monitoring Precision medicine

Development and validation of a predictive model for the pathological upgrading of gastric low-grade intraepithelial neoplasia: 《World Journal of Gastroenterology》2025年第11期63-73,共11页Kun-Ming Lyu Qian-Qian Chen Yi-Fan Xu Yao-Qian Yuan Jia-Feng Wang Jun Wan En-Qiang Ling-Hu; Supported by the National Key Research and Development Program of China,No.2022YFC2503600。; BACKGROUND The discrepancy between endoscopic biopsy pathology and the overall pathology of gastric low-grade intraepithelial neoplasia(LGIN)presents challenges in developing diagnostic and treatment protocols.AIM To ...; 关键词：Endoscopic resection Gastric low-grade intraepithelial neoplasia Early gastric cancer Pathological upgrade Prediction model

Role of interleukins in the pathogenesis of coronary heart disease:A literature review: 《World Journal of Cardiology》2025年第3期41-57,共17页Saira Rafaqat Azeem Azam Ramsha Hafeez Hamza Faseeh Maria Tariq Muhammad Asif Amber Arshad Iqra Noshair; Interleukins(ILs),a subset of cytokines,play a critical role in the pathogenesis of coronary heart disease(CHD)by mediating inflammation.This review article summarizes the role of ILs such as IL-1,IL-2,IL-3,IL-4,IL-5,...; 关键词：Coronary heart disease INTERLEUKINS Inflammation PATHOGENESIS

The Pathophysiologic Role of Oxidative Stress in Mitotic Cell Division: 《BIOCELL》2025年第3期419-435,共17页Nathan Isaac Dibal Martha Orendu Oche Attah; Oxidative stress is characterized by elevated intracellular reactive oxygen species(ROS)levels.At physiological levels,ROS work as signaling molecules,helping cells go through the cell cycle normally and keeping their...; 关键词：Cell cycle MITOSIS oxidative stress ROS

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