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TREATING: 作品数：1478被引量：3220H指数：23; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：李娜谢巧玲刘振寰蔡森林陈永亨更多>>; 相关机构：广州中医药大学第四军医大学西京医院中山大学江苏省中医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划上海市教育委员会重点学科基金广东省自然科学基金更多>>

Treating human cancer by targeting EZH2: 《Genes & Diseases》2025年第3期205-218,共14页Mengfei Xu Chunyan Xu Rui Wang Qing Tang Qichun Zhou Wanyin Wu Xinliang Wan Handan Mo Jun Pan Sumei Wang; supported by grants from the Research Fund for Bajian Talents of Guangdong Provincial Hospital of Chinese Medicine(China)(No.BJ2022KY13);the National Natural Science Foundation of China(No.82274602);the Foundation for Basic and Applied Research of Guangdong Province,China(No.2021A1515220023,2017B030314166);the Chinese Medicine Science and Technology Research Project of Guangdong Provincial Hospital of Chinese Medicine(China)(No.YN2019QJ06);the Guangzhou Science and Technology Plan Project(Guangdong,China)(No.2024A03J0548,202201020349);the Key Project of State Key Laboratory of Dampness Syndrome of Chinese Medicine Jointly Built by Province and Ministry(China)(No.SZ2021ZZ38);Guangdong Provincial Key Laboratory of Chinese Medicine for Prevention and Treatment of Refractory Chronic Diseases(China)(No.YN2023MB09);the Guangdong Traditional Chinese Medicine Project(China)(No.20231094,20241135).; Enhancer of zeste homolog 2 (EZH2), an epigenetic regulator that primarily inhibitsdownstream gene expression by tri-methylating histone H3, which is usually overexpressed intumors and participates in many processes s...; 关键词：CANCER Epigenetic modification EZH2 EZH2 inhibitor H3K27me3

Evaluating the efficacy of stem cells in treating severe dry eye disease: 《World Journal of Stem Cells》2025年第4期36-47,共12页Lanxing Fu Lucia Pelosini Nick Kopsachilis Roberta Foti Fabiana D’Esposito Mutali Musa Alberto D’Amico Daniele Tognetto Caterina Gagliano Marco Zeppieri; Dry eye disease(DED)is a multifactorial disorder that disturbs ocular surface equilibrium,considerably diminishing quality of life.Present therapies only offer symptomatic alleviation.Stem cell treatment,especially me...; 关键词：Dry eye disease Stem cell therapy Mesenchymal stem cells Corneal regeneration EXOSOME CORNEA Clinical trials

Is the use of a transanal drainage tube effective in treating anastomotic leakage for mid-low rectal cancer: 《World Journal of Clinical Oncology》2025年第4期102-108,共7页Yu-Kun Cao Shi-Lai Yang Zheng-Qiang Wei; BACKGROUND Anastomotic leakage(AL)is a severe surgical complication for mid-low rectal cancers.The efficacy of transanal drainage tube(TDT)has rarely been reported.AIM To evaluate the efficacy of TDT after AL.METHODS ...; 关键词：Rectal cancer Anastomotic leakage Transanal drainage tube Low anterior resection syndrome THERAPY

Vitreous surgery in treating complex retinal capillary hemangioma: 《International Journal of Ophthalmology(English edition)》2025年第4期748-750,共3页Wan Cheng Wei-Ling Yan Shi-Yong Li Ke-Ran Li; Supported by the Nanjing Science and Technology Development General Project(No.YKK23264).; Dear Editor,Retinal capillary hemangioma(RCH)is a benign vascular tumor that poses significant challenges due to its potential to cause vision impairment and retinal detachment(RD).We present a comprehensive case repo...; 关键词：SURGERY HEMANGIOMA CAPILLARY

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report: 《Neural Regeneration Research》2025年第4期1207-1216,共10页Pascal J.Goldschmidt-Clermont Aisha Khan George Jimsheleishvili Patricia Graham Adriana Brooks Risset Silvera Alexander J.P.Goldschmidt Damien D.Pearse W.Dalton Dietrich Allan D.Levi James D.Guest; support from the Miami Project to Cure Paralysis,the Buoniconti Fund,and the Interdisciplinary Stem Cell Institute(to AK,WDD,JDG,and ADL);the unconditional support of Dean Henri Ford of the Leonard M.Miller School of Medicine at the University of Miami.; Schwann cells are essential for the maintenance and function of motor neurons,axonal networks,and the neuromuscular junction.In amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann c...; 关键词：ALLOGENEIC amyotrophic lateral sclerosis EXOSOMES INFUSION neuromuscular junction Schwann cell

Androgen receptor inhibitors in treating prostate cancer: 《Asian Journal of Andrology》2025年第2期144-155,共12页Ryan N Cole Qinghua Fang Kanako Matsuoka Zhou Wang; supported in part by DOD Idea Development Award(HT9425-23-1-0295);NIH grants(R01 CA265897 and R21 CA280467);by the Department of Urology,University of Pittsburgh School of Medicine,Pittsburgh,PA,USA。; Androgens play an important role in prostate cancer development and progression.Androgen action is mediated through the androgen receptor(AR),a ligand-dependent DNA-binding transcription factor.AR is arguably the most...; 关键词：androgen receptor ANTI-ANDROGENS prostate cancer

Liposome of a synergistic combination of HDP-mimicking polymer and rifampicin for treating bacterial infections in aquaculture via oral administration: 《Science China Materials》2025年第4期1259-1270,共12页Haowen Yu Luhang Chen Yueming Wu Wenhui Dai Minzhang Chen Yuan Chen Longqiang Liu Jiangzhou Wang Xinqi Huang Kang Chen Runhui Liu; supported by the National Natural Science Foundation of China(T2325010,52203162,22075078);the National Key Research and Development Program of China(2022YFC2303100);the Fundamental Research Funds for the Central Universities(JKVD1241029,JKD01241701);the Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism(Shanghai Municipal Education Commission)。; The extensive use of antibiotics in high-density aquaculture has accelerated the emergence of antibiotic-resistant bacteria.The presence of antibiotics in water and soil,and their transmission through the food chain e...; 关键词：liposomes oral administration AQUACULTURE synergistic combinations Vibrio infections

Exploring the Efficacy of BMSC Transplantation via Various Pathways for Treating Cholestatic Liver Fibrosis in Mice: 《Biomedical and Environmental Sciences》2025年第4期447-458,共12页Junjie Ren Zixu Li Xinrui Shi Tingting Lyu Xiaonan Li Min Ge Qizhi Shuai Tingjuan Huang; supported by grants from the Natural Science Research Project of Shanxi Basic Research Program [20210302123246];the Scientific Research Project of Shanxi Provincial Health Commission [2020079];the Natural Science Foundation Youth Fund of Hebei Province[C2022402032];the Shanxi Province Higher Education “Billion Project” Science and Technology Guidance Project [BYJL036]。; Objective To compare the therapeutic efficacy of portal and tail vein transplantation of bone marrowderived mesenchymal stem cells(BMSCs) against cholestatic liver fibrosis in mice.Methods BMSCs were isolated and co-c...; 关键词：Bone marrow mesenchymal stem cells Portal vein Tail vein Cholestatic hepatic fibrosis Administration route

Application of Modified Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection in Treating Rectal Neuroendocrine Tumors and Prognostic Analysis: 《Journal of Clinical and Nursing Research》2025年第4期91-96,共6页Yan Chen Ying Chang; Clinical Study on Endoscopic Resection of Colorectal Submucosal Tumors Using Underwater Combined with Metal Clip-Assisted Snare,China(Grant No.2441ZF271)。; Objective:To analyze the application value of modified endoscopic mucosal resection(EMR)and endoscopic submucosal dissection(ESD)in rectal neuroendocrine tumors,with a view to providing new clinical options for the ea...; 关键词：Modified endoscopic mucosal resection Endoscopic submucosal dissection Rectal neuroendocrine tumor

Elucidating the mechanism of Kuwanon G in treating diabetic encephalopathy through network pharmacology:A comprehensive study: 《Journal of Chinese Pharmaceutical Sciences》2025年第3期251-259,共9页Yuqian Zhang Haiying Niu Xiaowei Zhang Weiwei Xie Kaiyue Zhang Lantong Zhang Yiran Jin; financially supported by the Hebei Administration of Traditional Chinese Medicine(Grant No.2024040)。; The present study employed network pharmacology to elucidate the molecular mechanism underlying the therapeutic effects of kuwanon G in diabetic encephalopathy.Utilizing the Pharmmapper databases,we identified potenti...; 关键词：Kuwanon G Network pharmacology Diabetic encephalopathy MECHANISM

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