supported by the National Natural Science Foundation of China(No.81802709);the Shandong Provincial Natural Science Foundation,China(Nos.ZR2023MH230,ZR2023MH096);the Shandong Provincial Postdoctoral Innovative Talents Funded Scheme;Plan of Young Scholars of Shandong University。
Immunotherapy offers significant potential but is often hampered by the immunosuppressive environment in oral squamous cell carcinoma(OSCC).To address this,we propose an enhanced immunotherapeutic strategy that revita...
supported by the National Key Basic Research Program(973 Project)(Grant Nos.2015CB931802 and 2017FYA0205301);the Special Fund for Science and Technology Innovation of Shanghai Jiao Tong University(Grant Nos.YG2017MS70,YG2015MS62,and AF0300179);the Shanghai Municipal Bureau of Economy and Information Technology(Grant No.XC-ZXSJ-02-2016-05);the National Natural Scientific Foundation of China(Grant Nos.8202010801,81921002,81225010,81028009,and 31170961);the 863 Project of China(Grant No.2014AA020700);and the Shanghai Science and Technology Fund(Grant No.13NM1401500)。
Objective:Although great progress has been made in the field of siRNA gene therapy,safe,efficient,and targeted delivery of siRNA are still major challenges in siRNA therapeutics.Methods:We developed an up-conversion n...