BACKGROUND Previous epidemiologic investigations have consistently demonstrated a strong association between the ratio of cholesterol to total lipids in medium very-lowdensity lipoprotein(VLDL)and the occurrence of pe...
This study was supported in part by the National Institutes of Health(NIH)funds P20GM144269,R01 DK134737&R56 DK129234(HMN).
Non-alcoholic fatty liver disease(NAFLD)is a highly prevalent form of liver disease associated with obesity,diabetes,and other metabolic diseases.1 NAFLD is characterized by hepatocyte lipid accumulation.Left untreate...
supported by National Natural Science Foundation of China (grant number 82070591);Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (grant number 2017BT01S131);Postdoctoral Science Foundation of China (grant number 2018M641919).
Background and Aims:RAS protein activator like 2(RASAL2)is a newly discovered metabolic regulator involved in energy homeostasis and adipogenesis.However,whether RASAL2 is involved in hepatic lipid metabolism remains ...
This work was supported by grants from Canadian Institutes of Health Research(PS 178091);the National Natural Science Foundation of China(NSFC 81929002);D.-W.Z.was also supported by grants from the Natural Sciences and Engineering Research Council of Canada(RGPIN-2016-06479);Canadian Institutes of Health Research(PS 155994);S.Q.was supported by 91539114,ts201511057,and Academic Promotion Program of Shandong First Medical University(2019QL010 and 2019PT009);Y.S.was partly supported by Motyl Graduate Studentships in Cardiac Sciences from the Faculty of Medicine and Dentistry at the University of Alberta.
Surfeit 4 is a polytopic transmembrane protein that primarily resides in the endoplasmic reticulum(ER)membrane.It is ubiquitously expressed and functions as a cargo receptor,mediating cargo transport from the ER to th...
Supported by the Pilot Project of Fujian Province(No.2016Y0067,No.2020Y0076,No.2020J05282);the Foundation of Key Research Plan of Shaanxi Province(No.2018SF-257);the Scientific Research Project of the 900th Hospital of Joint Logistic Support Force,PLA of 2018(No.2018Q02)。
AIM:To explore whether the retinal neovascularization(NV)in a genetic mutant mice model could be ameliorated in an inherited retinitis pigmentosa(RP)mouse,which would help to elucidate the possible mechanism and preve...