VLDL

作品数:188被引量:335H指数:9
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相关作者:屈伸冯宗忱刘秉文邓耀祖宗义强更多>>
相关机构:华中科技大学同济医科大学四川农业大学扬州大学更多>>
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产蛋间隔期母鸽卵黄前体及其受体基因的表达分析
《畜牧与兽医》2024年第10期8-13,共6页毛昕妍 郭振玉 邓子优 吴薛蓓 路淑敏 陈静 苗冬枝 王莹 
国家自然科学基金面上项目(32372875);江苏高校优势学科建设工程资助项目(PAPD)。
旨在探究产蛋间隔期鸽卵黄沉积相关基因的表达规律。选取12月龄白羽王鸽48对,分别在产蛋间隔(LI)第1天(LI1)、第3天(LI3)、第5天(LI5)和第7天(LI7)4个时期采集母鸽肝脏、卵巢、F1卵泡颗粒层和F1卵泡膜层样本,利用实时荧光定量PCR(RT-qP...
关键词: 卵黄沉积 APOB APO-VLDLⅡ VTG2 VLDLR 
化瘀祛痰方通过内质网应激PERK通路对ApoE^(-/-)小鼠肝脏VLDL的影响
《时珍国医国药》2024年第9期2130-2135,共6页杜莹 宋囡 冷雪 杨莹 王杰 吕美君 贾连群 
国家自然科学基金(82104552);辽宁省教育厅面上项目(LJKMZ20221316);辽宁中医药大学自然科学类重点项目(2021LZY038);辽宁省科技计划联合计划(基金项目)(2023-MSLH-186)。
目的观察化瘀祛痰方对ApoE^(-/-)小鼠肝脏VLDL的影响,探讨其可能的作用机制。方法32只ApoE^(-/-)小鼠随机分为模型组、中药组(化瘀祛痰方组)、中药+4-PBA组(化瘀祛痰方+4-PBA组)、4-PBA组,每组8只,另取8只同龄C57BL/6J小鼠作为正常组。...
关键词:化瘀祛痰方 动脉粥样硬化 内质网应激 PERK通路 VLDL 
Causal associations between intermediate very-low-density lipoprotein cholesterol-to-total lipids ratio and peptic ulcer:A bidirectional Mendelian randomization study
《World Journal of Clinical Cases》2024年第25期5729-5738,共10页Chun-Mei Lin Qian Meng Ying-Jun Li Shuang-Xi Zhang Qiong-Xi Luo Zhen-Yu Dai 
BACKGROUND Previous epidemiologic investigations have consistently demonstrated a strong association between the ratio of cholesterol to total lipids in medium very-lowdensity lipoprotein(VLDL)and the occurrence of pe...
关键词:Ratio of cholesterol to total lipids in medium VLDL Peptic ulcer Mendelian randomization Casual effect Single nucleotide polymorphism 
NLR VLDL TPP与CABG术后静脉桥血管狭窄类病变的关联性及联合预测价值
《临床心身疾病杂志》2023年第5期57-62,共6页翟少峰 王永生 张宪芬 韩婉青 张俊伟 
河南省医学科技攻关计划项目(编号2018092166)。
目的 探讨中性粒细胞与淋巴细胞比值、极低密度脂蛋白、血栓前体蛋白与冠状动脉旁路移植术后静脉桥血管狭窄类病变的关联性及联合预测分析。方法 将125例行冠状动脉旁路移植术患者根据冠状动脉造影检查结果分为狭窄组70例,非狭窄组55例...
关键词:中性粒细胞与淋巴细胞比值 极低密度脂蛋白 血栓前体蛋白 冠状动脉旁路移植术 静脉桥血管狭窄类病变 关联性 预测价值 
Loss of hepatic VMP1 trapped VLDL in the bilayer of endoplasmic reticulum membrane
《Liver Research》2023年第2期161-163,共3页Hong-Min Ni Benjamin Ding Allen Chen 
This study was supported in part by the National Institutes of Health(NIH)funds P20GM144269,R01 DK134737&R56 DK129234(HMN).
Non-alcoholic fatty liver disease(NAFLD)is a highly prevalent form of liver disease associated with obesity,diabetes,and other metabolic diseases.1 NAFLD is characterized by hepatocyte lipid accumulation.Left untreate...
关键词:AUTOPHAGY Lipid droplet Non-alcoholic fatty liver disease(NAFLD) Non-alcoholic steatohepatitis(NASH) 
RASAL2 Deficiency Attenuates Hepatic Steatosis by Promoting Hepatic VLDL Secretion via the AKT/TET1/MTTP Axis
《Journal of Clinical and Translational Hepatology》2023年第2期261-272,共12页Hao Ding Jiang-Hong Yu Ge Ge Yan-Yun Ma Jiu-Cun Wang Jun Zhang Jie Liu 
supported by National Natural Science Foundation of China (grant number 82070591);Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (grant number 2017BT01S131);Postdoctoral Science Foundation of China (grant number 2018M641919).
Background and Aims:RAS protein activator like 2(RASAL2)is a newly discovered metabolic regulator involved in energy homeostasis and adipogenesis.However,whether RASAL2 is involved in hepatic lipid metabolism remains ...
关键词:Nonalcoholic fatty liver disease RASAL2 Very low-density lipoprotein STEATOSIS Lipid metabolism 
Surf4,cargo trafficking,lipid metabolism,and therapeutic implications被引量:1
《Journal of Molecular Cell Biology》2022年第9期3-13,共11页Yishi Shen Hong-Mei Gu Shucun Qin Da-Wei Zhang 
This work was supported by grants from Canadian Institutes of Health Research(PS 178091);the National Natural Science Foundation of China(NSFC 81929002);D.-W.Z.was also supported by grants from the Natural Sciences and Engineering Research Council of Canada(RGPIN-2016-06479);Canadian Institutes of Health Research(PS 155994);S.Q.was supported by 91539114,ts201511057,and Academic Promotion Program of Shandong First Medical University(2019QL010 and 2019PT009);Y.S.was partly supported by Motyl Graduate Studentships in Cardiac Sciences from the Faculty of Medicine and Dentistry at the University of Alberta.
Surfeit 4 is a polytopic transmembrane protein that primarily resides in the endoplasmic reticulum(ER)membrane.It is ubiquitously expressed and functions as a cargo receptor,mediating cargo transport from the ER to th...
关键词:VLDL secretion cargo receptor PCSK9 lipid metabolism atherosclerosis TRAFFICKING 
ApoB100对肝脏VLDL合成分泌的影响及其在兽医临床中的研究进展被引量:2
《现代畜牧兽医》2022年第7期89-93,共5页范文文 王爽 高畅鸿 田艳 邹存志 徐闯 张冰冰 杨威 
国家自然基金项目(U20A2062);黑龙江省博士后科研启动项目(2020-51)。
肝脏可从循环中获得脂质,进行合成并将脂质中的脂蛋白分泌至血液中,在全身新陈代谢的动态平衡中起到核心作用。极低密度脂蛋白(VLDL)是肝脏的主要分泌产物,其主要作用是向外周组织运输内源性合成的脂类,如甘油三酯(TG)等。载脂蛋白B100 ...
关键词:肝脏 极低密度脂蛋白 载脂蛋白B100 自噬 降解 
Retinal neovascularization induced by mutant Vldlr gene inhibited in an inherited retinitis pigmentosa mouse model:an in-vivo study
《International Journal of Ophthalmology(English edition)》2021年第7期990-997,共8页Wei-Ming Yan Pan Long Mei-Zhu Chen Dong-Yu Wei Jian-Cong Wang Zuo-Ming Zhang Lei Zhang Tao Chen 
Supported by the Pilot Project of Fujian Province(No.2016Y0067,No.2020Y0076,No.2020J05282);the Foundation of Key Research Plan of Shaanxi Province(No.2018SF-257);the Scientific Research Project of the 900th Hospital of Joint Logistic Support Force,PLA of 2018(No.2018Q02)。
AIM:To explore whether the retinal neovascularization(NV)in a genetic mutant mice model could be ameliorated in an inherited retinitis pigmentosa(RP)mouse,which would help to elucidate the possible mechanism and preve...
关键词:retinitis pigmentosa retinal neovascularization Pde6b gene Vldlr gene PHOTORECEPTOR 
管敏团队在非酒精性脂肪肝疾病机制的研究取得进展
《集成技术》2021年第2期123-123,共1页
中国科学院深圳先进技术研究院人体组织与器官退行性研究中心管敏团队在非酒精性脂肪肝病/非酒精性脂肪肝炎疾病发生的机理取得进展。相应成果"Dysfunction of estrogenrelated receptor alpha-dependent hepatic VLDL secretion contri...
关键词:非酒精性脂肪肝病 非酒精性脂肪肝炎 中国科学院 VLDL 
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