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A cucurbit[8]uril-based supramolecular phosphorescent assembly:Cell imaging and sensing of amino acids in aqueous solution: 《Chinese Chemical Letters》2024年第12期165-168,共4页Qian Ren Xue Dai Ran Cen Yang Luo Mingyang Li Ziyun Zhang Qinghong Bai Zhu Tao Xin Xiao; supported by the National Natural Science Foundation of China(No.22361011);Guizhou Provincial Science and Technology Projects(No.ZK[2023]General 040)。; In recent years,host-guest interactions of macrocycles have emerged as a promising approach to effectively enhance pure organic room-temperature phosphorescence by inhibiting the nonradiative relaxation while isolatin...; 关键词：CUCURBITURIL Isobromoquinoline Pure organic room-temperature PHOSPHORESCENT Cell imaging Amino acid

Chiral amino acid recognition in water:A BINOL-based fluorescent probe被引量：3: 《Chinese Chemical Letters》2023年第12期136-140,共5页Meng-Xin Sun Chuan-Zhi Ni Fang-Qi Zhang Yuan-Yuan Zhu Jie Zeng Shuang-Xi Gu; financial support from the National Natural Science Foundation of China(Nos.21877087,22074114);Natural Science Foundation of Hubei Province of China(Nos.2020CFB623,2021CFB556);Key Laboratory for Green Chemical Process of Ministry of Education(No.GCP20200201);Hubei Key Laboratory of Novel Reactor and Green Chemical Technology(No.40201002);Wuhan Institute of Technology Graduate Education and Teaching Reform Research Project(Nos.2022JYXM09,2021JYXM07);Wuhan Institute of Technology Graduate Innovation Fund(Nos.CX2022450,CX2022009,CX2022058)are greatly appreciated.; A novel BINOL-based fluorescence probe(S)-6 featuring a sodium sulfonate fragment at the 2'-position was designed and synthesized via simple synthetic procedures under mild reaction conditions.The watersoluble probe(S...; 关键词：Chiral recognition Fluorescent probe Amino acid WATER-SOLUBLE Enantiomeric excess determination

Therapeutic poly(amino acid)s as drug carriers for cancer therapy: 《Chinese Chemical Letters》2023年第6期81-89,共9页Huihui Hu Zhen Zhang Yifen Fang Lei Chen Jun Wu; supported by the National Natural Science Foundation of China(Nos.51973243 and 52173150);the Shenzhen Basic Research Project(No.JCYJ20190807155801657);the International Cooperation and Exchange of the National Natural Science Foundation of China(No.51820105004)。; As one of the top global health problems,the effective treatment of cancer is one of the most urgent clinical challenges.Currently,the main treatments for cancer include surgery,chemotherapy,radiotherapy,and gene ther...; 关键词：Poly(amino acid)s IMMUNOMODULATORY ANTIOXIDANT ANTI-INFLAMMATORY Apoptosis-promoting

Chiroptical coassemblies between organic carboxylic acids and amino acid derivatives with C_(3)-symmetry被引量：2: 《Chinese Chemical Letters》2023年第6期319-322,共4页Yiran Xia Aiyou Hao Pengyao Xing; supported by the National Natural Science Foundation of China(Nos.21901145,22171165);the financial support from Youth Cross-Scientific Innovation Group of Shandong University(No.2020QNQT003)。; Benzimidazole amino acid derivatives behave as supramolecular hosts to include organic acids via complementary hydrogen bonding whereby supramolecular chirality and chiroptical properties could be manipulated.Organic ...; 关键词：Supramolecular chirality Organic carboxylic acid Amino acid Coassembly Chiroptical property

Trimetaphosphate-induced chiral selection between amino acid and nucleoside using ^(15)N-^(31)P coupling NMR被引量：1: 《Chinese Chemical Letters》2022年第2期821-824,共4页Jianxi Ying Ruiwen Ding Yumeng Zhang Bowen Han Yeting Guo Ning Wang Dandan Guo Yile Wu Junwei Huang Yan Liu Feng Ni Shaohua Huang Yufen Zhao; supported by the National Natural Science Foundation of China (Nos.91856126,42003062,21778042 and 41876072);Scientific Research Grant of Ningbo University (No.215432000282);Ningbo Top Talent Project (No.215-432094250)。; Life on Earth uses a common set of L-amino acids(L-aa)to construct proteins and D-nucleosides(D-Nu)to form nucleic acids,which serve as the carrier of genetic information.Herein,we reveal the in-trinsic mechanism of c...; 关键词：Chiral selection Amino acids NUCLEOSIDES Prebiotic chemistry Origin of life

Drug-induced hierarchical self-assembly of poly(amino acid)for efficient intracellular drug delivery被引量：1: 《Chinese Chemical Letters》2021年第4期1563-1566,共4页Zifen Li Yanxue Yang Chuan Peng Hang Liu Rui Yang Yi Zheng Lulu Cai Hong Tan Qiang Fu Mingming Ding; supported by the National Natural Science Foundation of China(Nos.51873118,21474064,52022062);the KeyResearch and Development Program of Science and Technology Department of Sichuan Province(No.2019YFS0514);Science and Technology Project of Chengdu(No.2019-YF05-00784-SN);the Project of State Key Laboratory of Polymer Materials Engineering(No.sklpme2020-2-03);the Fundamental Research Funds for Central Universities。; As a potent anticancer drug,gambogic acid(GA)suffers from its poor water solubility and low chemical stability and shows a limited clinical outcome.To address this problem,we report here a simple and effective strateg...; 关键词：Poly(amino acid)s Electrostatic complexation Gambogic acid Hierarchical self-assembly Secondary conformation

Achieving room temperature phosphorescence from organic small molecules on amino acid skeleton: 《Chinese Chemical Letters》2020年第11期2929-2932,共4页Zifei Wang Teng Li Bingbing Ding Xiang Ma; the National Natural Science Foundation of China(NSFC,Nos.21788102,21722603 and 21871083);Shanghai Municipal Science and Technology Major Project(No.2018SHZDZX03);‘Shu Guang’Project supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation(No.19SG26);the Innovation Program of Shanghai Municipal Education Commission(No.2017-01-07-00-02-E00010);Fundamental Research Funds for the Central Universities。; Room temperature phosphorescence(RTP)generated by small molecules has attracted great attention due to their unique potentials for biosensor,bioimaging and security protection.While,the design of RTP materials is extr...; 关键词：Room temperature phosphorescence Amino acid PHENYLALANINE Diphenylalanine

Structural characterizations of protonated homodimers of amino acids:Revealed by infrared multiple photon dissociation(IRMPD) spectroscopy and theoretical calculations被引量：3: 《Chinese Chemical Letters》2018年第9期1333-1339,共7页Lifu Ma Juan Ren Ruxia Feng Kailin Zhang Xianglei Kong; supported by the National Natural Science Foundation of China(Nos.21475065,21627801 and 11704280); Infrared multiple photon dissociation （IRMPD） spectroscopic and theoretical studies of protonated homodimers of amino acids generated by electrospray ionization in the gas phase have been reviewed. Results show that...; 关键词：Amino acid HOMODIMER IRMPD spectroscopy Proton affinity Charge-solvated Salt-bridged ESI mass spectrometry

Efficient preparation of β-hydroxy aspartic acid and its derivatives: 《Chinese Chemical Letters》2018年第7期1113-1115,共3页Long Liu Bo Wang Cheng Bi Gang He Gong Chen; the National Natural Science Foundation of China(Nos. 21421062, 21672105, 91753124) for financial support of this work; We report an efficient and practical synthetic route to various properly-protected erythreo-β-OH-Asp compounds, which are key β-branched a-amino acid units in coralmycin A and other peptide natural products. Fmoc an...; 关键词：Amino acid Natural product Erythreo-β-OH-Asp Erythreo-β-OMe-Asn ANTIBIOTICS

Effects of linker amino acids on the potency and selectivity of dimeric antimicrobial peptides被引量：2: 《Chinese Chemical Letters》2018年第7期1163-1166,共4页Ming Kai Wei Zhang Huan Xie Liwei Liu Sujie Huang Xiao Li Zhengzheng Zhang Yuyang Liu Bangzhi Zhang Jingjing Song Rui Wang; the National Natural Science Foundation of China(Nos. 81773566, 21602092, 81473095);the Fundamental Research Funds for the Central Universities(Nos. lzujbky-2017-134, lzujbky-2017-120, lzujbky-2016-21); Dimerization is an effective strategy for designing antimicrobial peptides that combine the advantages of different native peptides. In this study, we explored the effects of different linker amino acids, including le...; 关键词：Linker amino acid Flexibility Heteromeric antimicrobial peptides Potency and selectivity

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