This work was supported by the National Program on Key Basic Research Project of China (973 Program; 2015CB964902), the National Natural Science Foundation of China (NSFC; H81170466 and H81370597), and the CAMS Initiatives for Innovative Medicine (2016-12M-1-018) awarded to F.M.
RUNXI is absolutely required for definitive hematopoiesis, but the function of RUNXlb/c, two isoforms of human RUNX1, is unclear. We established inducible RUNXlb/c-overexpressing human embryonic stem cell (hESC) lin...
本研究旨在探讨AML1/ETO融合基因阳性的急性髓系白血病M2(acute myeloid leukemia with maturation,AML/M2)患者FLT3基因表达量与临床症状和预后的相关性及其意义。采用RQ-PCR法定量检测21例AML1/ETO阳性AML-M2患者初诊骨髓标本中FLT3...
目的探讨GATA-2基因在AML1/ETO融合基因阳性急性髓系白血病M2(acute myeloid leukemia with maturation,AML/M2)患者中的表达状况。方法利用实时荧光定量PCR(RQ-PCR)法对23例AML1/ETO阳性AML-M2患者初诊骨髓标本中GATA-2基因的表达...