云南高校图书馆联盟文献共享服务平台- ANTI-TUMOR

ANTI-TUMOR: 作品数：366被引量：1036H指数：14; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：李瑞赵浩如林以宁张晗星李彦更多>>; 相关机构：北京大学中国药科大学重庆医科大学山东大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>

Doxorubicin-loaded bacterial outer-membrane vesicles exert enhanced anti-tumor efficacy in non-small-cell lung cancer被引量：19: 《Acta Pharmaceutica Sinica B》2020年第8期1534-1548,共15页Kudelaidi Kuerban Xiwen Gao Hui Zhang Jiayang Liu Mengxue Dong Lina Wu Ruihong Ye Meiqing Feng Li Ye; sponsored by Scientific and Innovative Action Plan of Shanghai(No.18431902800,China);National Natural Science Foundation of China(No.81572979);Project of Shanghai Health and Family Planning Commission(201940102,China);National Key Basic Research Program of China(2015CB931800); More efficient drug delivery system and formulation with less adverse effects are needed for the clinical application of broad-spectrum antineoplastic agent doxorubicin(DOX). Here we obtained outer-membrane vesicles(O...; 关键词：NUDE loaded outer

Immune-adjuvant loaded Bi2Se3 nanocage for photothermal-improved PD-L1 checkpoint blockade immune-tumor metastasis therapy被引量：2: 《Nano Research》2019年第8期1770-1780,共11页Yilin Song Yidan Wang Siyu Wang Yu Cheng Qianglan Lu Lifang Yang Fengping Tan Nan Li; supported by the National Basic Research Project (973 Program) of China (No.2014CB932200);the National Natural Science Foundation of China (Nos.81503016, 81771880, and 81401453);the Application Foundation and Cutting-edge Technologies Research Project of Tianjin (Young Program)(No.15JCQNJC13800).; Checkpoint blockade based immune therapy has shown to be effective but benefit only the minority of patients whose tumors have been pre-infiltrated by T cells. To overcome this obstacles, a PEG-modified Bi2Se3 nanocag...; 关键词：Bi2Se3 NANOCAGE R848 checkpoint BLOCKADE photothermal-immune THERAPY ANTI-TUMOR metastasis

Design,synthesis and anti-tumor activities of cyclic phosphoramidate mustard-quinazoline conjugates被引量：1: 《Journal of Chinese Pharmaceutical Sciences》2017年第10期727-736,共10页陈加贝郑育奋孔维崎李鑫罗来春韩彦君林松文孙崎葛泽梅李润涛; Ministry of Science and Technology of China(Grant No.2012ZX09103101-042); A series of new cyclic phosphoramidate mustard-quinazoline conjugates were designed and synthesized based on the drug candidate EMB-3, a multi-target-directed ligand against tumor cells, and their anti-tumor activitie...; 关键词：Phosphoramidate mustard conjugate ANTI-TUMOR Breast cancer EGFR/HER2

A novel nanogel delivery of poly-α,β-polyasparthydrazide by reverse microemulsion and its redox-responsive release of 5-Fluorouridine被引量：1: 《Asian Journal of Pharmaceutical Sciences》2016年第6期735-743,共9页Jingwen Guo Yan Wang Jing Wang Xin Zheng Di Chang Siling Wang Tongying Jiang; National Basic Research Program of China(973 Program)(No.2015CB932100);National Natural Science Foundation of China(No.81473165);Liaoning Provincial Key Laboratory of Drug Preparation Design&Evaluation of Liaoning Provincial Education Department(LZ2014045);Liaoning Provincial Key Laboratory of Studying the Modern Drug preparations.; To achieve GSH-responsive 5-Fluorouridine(5-FU) delivery, a novel family of nanogel drug carriers has been successfully prepared. The new class of PAHy-based nanogels was prepared by the crossing-link reaction of poly...; 关键词：PAHy-based NANOGEL High drug loading Redox-responsivity RELEASE properties SIGNIFICANT ANTI-TUMOR therapeutic efficacy

Co-delivery of doxorubicin and quercetin via mPEG-PLGA copolymer assembly for synergistic anti-tumor efficacy and reducing cardio-toxicity被引量：11: 《Science Bulletin》2016年第21期1689-1698,共10页Waseem Akhtar Qureshi Ruifang Zhao Hai Wang Tianjiao Ji Yanping Ding Ayesha Ihsan Ayeesha Mujeeb Guangjun Nie Yuliang Zhao; Acknowledgments This work was supported by the National Basic Research Program of China （2012CB934004）, the National Funds for Distinguished Young Scientists （31325010）, the Key Research Program of the Chinese Academy of Sciences （KGZD-EW-T06） and the National Natural Science Foundation of China （31300822）.; Quercetin （Que） is a natural multifunctional bioflavonoid, and has shown great potential for reducing adverse side effects and enhancing antitumor efficacy of chemotherapeutic drugs. However, its clinical applicatio...; 关键词：Polymeric nanoparticles . Doxorubicin Quercetin - Cardio-toxicity - Cancer therapy

The anti-tumor efficacy of c9,t11-CLA-PTX and t10,c12-CLA-PTX on MCF-7 breast cancer cells:in vitro and in vivo: 《Journal of Chinese Pharmaceutical Sciences》2014年第11期751-759,共9页杨科李星火李丹柯曦宇张烜张强; National Natural Science Foundation of China (Grant No.81172992);the National Basic Research Program of China (973 Program,Grant No.2013CB932501);Innovation Team of Ministry of Education (Grant No.BMU20110263); Considering the results of our previous research that conjugated linoleic acid mixture-paclitaxel （CLA-mixture-PTX） possesses anti-tumor activity against melanoma and brain glioma, the purpose of this study was to i...; 关键词：C9 tl 1-CLA-PTX T10 c12-CLA-PTX Apoptosis Cell cycle Cellular uptake Anti-tumor efficacy

Efficient induction of a Her2-specific anti-tumor response by dendritic cells pulsed with a Hsp70L1–Her2_(341–456) fusion protein被引量：3: 《Cellular & Molecular Immunology》2011年第5期424-432,共9页Qiang Fu Yanfeng Wu Fang Yan Ning Wang Wenying Wang Xuetao Cao Yajie Wang Tao Wan; supported by the Major Program of the Shanghai Committee of Science and Technology Development(QF,06DZ19010);the National High Technology Research and Development Program of China(YFW,2009AA02Z102);the National Natural Science Foundation of China(YFW,30872296);the National Science and Technology Major Project of the Ministry of Science and Technology of China(TWan,2008ZX09101-043).; Heat shock proteins(HSPs)have been shown to interact with antigen-presenting cells(APCs),especially dendritic cells(DCs).HSPs act as potent adjuvants,inducing a Th1 response,as well as antigen-specific CD8^(+) cytotox...; 关键词：CTL dendritic cell heat shock protein HER2/NEU immunotherapy

Trichosanthin enhances anti-tumor immune response in a murine Lewis lung cancer model by boosting the interaction between TSLC1 and CRTAM被引量：12: 《Cellular & Molecular Immunology》2011年第4期359-367,共9页Yuchan Cai Shudao Xiong Yijie Zheng Feifei Luo Pei Jiang Yiwei Chu; the National Key Technologies R&D Program of China during the Eleventh Five-Year Plan Period(2009ZX10004-104 and 2009ZX09301-011);National Science Foundation of China(30872378 and 81072408);the Science and Technology Commission of Shanghai Municipality(10JC1401100)in China and National 973 Project(2010CB912603 and 2011CB910400)in China.We thank the editors of Editage Company for professional editing of the article.; Trichosanthin(TCS),extracted from the Chinese medicinal herb Trichosanthes kirilowi,has shown promise for the inhibition of tumor growth.However,its immunomodulatory effect on tumor–host interaction remains unknown.I...; 关键词：anti-tumor immunity CRTAM immune protection TRICHOSANTHIN TSLC1

Anti-tumor Immune Response Mediated by Newcastle Disease Virus HN Gene被引量：1: 《Chemical Research in Chinese Universities》2011年第2期282-286,共5页PENG Li-ping LI Xiao SUN Li-li WEN Zhong-mei LIU Yan GAO Peng HUANG Hai-yan PIAO Bing-guo JIN Jing J1N Ning-yi; Supported by National High-Tech Research and Development Program of China(No.2007AA021004);the National Basic Research Program of China(No.2005CB523005);the National Natural Science Foundation of China(No.30771609);the National Science and Technology Major Project of China(Nos.2008ZX10004-015; 2009ZX08006-002B); Hemagglutinin-neuramidinase（HN） is one of the most important surface structure proteins of the Newcastle disease virus（NDV）. HN not only mediates receptor recognition but also possesses neuraminidase（NA） activit...; 关键词：HN gene Recombined adenovirus CYTOKINE Cell immunity Anti-tumor activity

Anti-tumor targeted drug delivery systems mediated by aminopeptidase N/CD13被引量：4: 《Acta Pharmaceutica Sinica B》2011年第2期80-83,共4页Xun Wang Bin Wang Qiang Zhang; This research was supported by the National Basic Research Program of China(No.2009CB930300);State Key Projects(No.2009ZX09310-001);the 863 Project(No.2007AA021811).; Aminopeptidase N(APN)/CD13 is a transmembrane glycoprotein,which is overexpressed on tumor neovascular endothelial cells and most tumor cells,where it plays an important role in tumor angiogenesis.Peptides containing ...; 关键词：Aminopeptidase N/CD13 NGR peptides ANTI-TUMOR Targeted drug delivery system

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