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作品数:684被引量:1903H指数:20
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相关领域:医药卫生更多>>
相关作者:王璐王良成张强张昆常立民更多>>
相关机构:重庆斯托纳科技有限公司吉林大学中南大学兰州交通大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>
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Corrigendum: Interconnections between diabetic corneal neuropathy and diabetic retinopathy: diagnostic and therapeutic implications
《Neural Regeneration Research》2025年第12期3415-3415,共1页
PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives
《Neural Regeneration Research》2025年第10期2758-2775,共18页Tianlong Liu Xiaolin Li Xiaowei Zhou Wei Chen Aidong Wen Minna Liu Yi Ding 
supported by the National Natural Science Foundation of China,Nos.82274313(to YD),82204746(to ML),82003982(to TL).
It has been reported that the PI3K/AKT signaling pathway plays a key role in the pathogenesis of ischemic stroke.As a result,the development of drugs targeting the PI3K/AKT signaling pathway has attracted increasing a...
关键词:apoptosis autophagy inflammation ischemic stroke NEUROPROTECTION oxidative stress PATHOGENESIS phosphatidylinositol 3-kinase protein kinase B THERAPEUTICS 
Role of peripheral amyloid-β aggregates in Alzheimer’s disease: mechanistic, diagnostic, and therapeutic implications
《Neural Regeneration Research》2025年第4期1087-1089,共3页Nazaret Gamez Rodrigo Morales 
supported by grants from NIH(RF1AG072491 and R01AI132695)to RM.
Compelling evidence demonstrates that the levels of peripheral amyloid-β(Aβ)fluctuate in Alzheimer’s disease(AD)patients.Moreover,Aβdeposits have been identified in peripheral tissues.However,the relevance of peri...
关键词:therapeutic AMYLOID latter 
Construction and validation of a novel SUMOylation-related IncRNAs signature for predicting the prognosis,tumor immune microenvironment,and therapeutic sensitivity of lung adenocarcinoma
《Genes & Diseases》2025年第2期102-105,共4页Jie Cai Weizhong Ruan Zida Wang Gongzhe Liu Bei Yang Hao Wang Deping Zhao Chang Chen Xiaogang Zhao 
supported by the Shanghai Sailing Program (China) (No.22YF1437600 to J.C.);the Programs of Shanghai Pulmonary Hospital (China) (No.fkzr2477 to J.C.).
Lung adenocarcinoma(LUAD)is the most prevalent subtype of lung cancer and the leading cause of cancer deaths worldwide.1 Despite immunotherapy,radiotherapy,and chemotherapy advances,treatment outcomes remain unsatisfa...
关键词:ADENOCARCINOMA PROGNOSIS lung 
Potential role and therapeutic implications of glutathione peroxidase 4 in the treatment of Alzheimer's disease
《Neural Regeneration Research》2025年第3期613-631,共19页Yanxin Shen Guimei Zhang Chunxiao Wei Panpan Zhao Yongchun Wang Mingxi Li Li Sun 
supported by the National Natural Science Foundation of China,No.82071442 (to LS);a grant from the Jilin Provincial Department of Finance,No.JLSWSRCZX2021-004 (to LS)。
Alzheimer's disease is an age-related neurodegenerative disorder with a complex and incompletely understood pathogenesis. Despite extensive research, a cure for Alzheimer's disease has not yet been found. Oxidative st...
关键词:apoptosis ferroptosis inflammation lipid peroxidation natural plant products neurodegenerative disorder NEUROPROTECTION oxidative stress small-molecule drugs 
Clinical,laboratory,and therapeutic differences between immunoglobulin E-mediated and non-immunoglobulin E-mediated cow’s milk protein allergy in children
《World Journal of Clinical Pediatrics》2025年第1期78-92,共15页Hasan M Isa Marwa J Abdulnabi Nawra S Naser Fatema N Lahmda Noor M AlAnsari Zahra H Isa Afaf M Mohamed 
BACKGROUND Although breast milk is ideal for newborns,in some cases,it is replaced with cow’s milk,which contains proteins that increase the risk of cow’s milk protein allergy(CMPA).AIM To evaluate CMPA prevalence i...
关键词:CHILDREN Milk allergy Immunoglobulin E BREASTFEEDING Infant formula Bahrain 
Modern perspectives on the traditional uses, phytochemical profiles, and therapeutic benefits of Syzygium cumini
《Integrative Medicine Discovery》2025年第7期1-13,共13页Virender Kumar Naveen Khatri Davinder Kumar Manisha Shekhawat Vandana Garg Ashwani Kumar Saloni Kakkar 
Syzygium cumini Linn.,commonly known as Jamun,is a member of the Myrtaceae family and is also referred to by synonyms such as Eugenia djouant Perr.,Eugenia cumini,Eugenia jambolana Lam.,Syzygium jambolana Lam.,and Myr...
关键词:ANTIOXIDANT glycaemic index bioactive substances pharmacological properties GASTROPROTECTIVE radical scavenger capacity 
Emerging roles of the acid sphingomyelinase/ceramide pathway in metabolic and cardiovascular diseases:Mechanistic insights and therapeutic implications
《World Journal of Cardiology》2025年第2期9-21,共13页Hong-Ni Wang Ye Wang Si-Yao Zhang Lan Bai 
Supported by Ganzhou City’s“Light of the Soviet Area”Talent Project,No.GZSQZG202301009。
Metabolic diseases have emerged as a leading cause of mortality from non-communicable diseases,posing a significant global public health challenge.Al-though the association between ceramides(Cers)and metabolic disease...
关键词:Acid sphingomyelinase CERAMIDE Metabolic and cardiovascular diseases Glycolipid metabolism Inflammation Mitochondrial homeostasis 
Epidemiological, Clinical and Therapeutic Aspects of Acute Respiratory Distress in Children in Medical Emergencies at the Bangui Pediatric University Hospital
《Open Journal of Pediatrics》2025年第1期111-118,共8页Simplice Cyriaque Kango Marie Christine Awa Sepou Yanza Jess Elio Kosh Komba Mireille Mandé-Njapou Jean Chrysostome Gody 
Introduction: Respiratory distress is a clinical condition accompanied by an increase in work of breathing, with the respiratory accessory muscles brought into play to ensure normal arterial oxygenation. It is a major...
关键词:Respiratory Distress Medical Emergencies Pediatric University Hospital Bangui 
Heterogeneity of anoikis in triple-negative breast cancer subtyping and therapeutic implications
《Genes & Diseases》2025年第1期114-117,共4页Kun Fang Suxiao Jiang Zhengjie Xu Meng Luo Changsheng Yan 
supported by a Ningxia Reproductive Disease Clinical Medical Research Center Project(2023-LCYX003);Ningxia Hui Autonomous Region Natural Science Foundation Project(2022AAC03748);Ningxia Hui Autonomous Region Natural Science Foundation Project(2021AAC03523);Yinchuan Science and Technology Innovation Project(2023SF25);Basic research project of Yinchuan Maternal and Child Health Hospital(2022NYFYCX05);Basic research project of Yinchuan Maternal and Child Health Hospital(2023NYFYCX01).
Triple-negative breast cancer(TNBC)is an inherently heterogeneous malignancy at the biological and clinical levels,occupying around 15%of diagnosed breast cancer cases and being the most lethal breast cancer subtype t...
关键词:BREAST cancer clinical 
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