supported by the Natural Science Foundation of Hebei Province(No.H2020209284,China,Dayong Zheng);Scientific Research Foundation of Higher Education Institutions of Hebei Province(No.QN2021120,Dayong Zheng);Department of Science and Technology of Liaoning province(No.2020-MS-225,China,Jun Li);the Montefiore Einstein Cancer Center grant(NCI P30CA013330,USA,Edward Chu)。
Aurora kinase A(Aurora-A),a serine/threonine kinase,plays a pivotal role in various cellular processes,including mitotic entry,centrosome maturation and spindle formation.Overexpression or gene-amplification/mutation ...