CANCER_CELL

作品数：221被引量：567H指数：13
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相关作者：郭鹏曾津芮红兵陈元仲陈炜更多>>
相关机构：西安交通大学医学院第一附属医院北京大学西安交通大学福建医科大学更多>>
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Synergistic anti-tumor therapy by a homotypic cell membranecloaked biomimetic nanocarrier with exceptionally potent activity against hepatic carcinoma被引量：3
《Nano Research》2022年第9期8255-8269,共15页Shini Feng Pinyue Ni Yan Gong Bijiang Geng Hui Li Chenlin Miao Ruyu Fan Levon Galstyan Dengyu Pan Fuxue Chen Huafei Li 
“One Belt One Road”International Cooperation Project of Shanghai Municipal Committee of Science and Technology(No.19410740900);the National Natural Science Foundation of China(No.52002239);the International Science and Technology Cooperation Programme of Ministry of Science and Technology of China(No.2019YFE0116800);Natural Science Foundation of Shanghai(No.21ZR1422800).
Hepatic carcinoma(HC)is the sixth most frequently occurring malignancies and the third leading cause of cancer death worldwide.Sepantronium bromide(YM155)is a small molecule inhibitor of survivin,which has broad-spect...
关键词：hepatic carcinoma sepantronium bromide(YM155) cancer cell membrane biomimetic drug delivery system graphene quantum dots photothermal effect 
Specific generation of nitric oxide in mitochondria of cancer cell for selective oncotherapy被引量：2
《Nano Research》2022年第6期5273-5278,共6页Mengyu Sun Yanjuan Sang Qingqing Deng Zhengwei Liu Jinsong Ren Xiaogang Qu 
supported by the National Key R&D Program of China(No.2021YFF1200701);the National Natural Science Foundation of China(Nos.91856205,21820102009,and 21871249);the Key Program of Frontier of Sciences(No.CAS QYZDJ-SSW-SLH052)。
Nitric oxide(NO)gas therapy,especially,L-arginine(L-Arg)-based NO treatment strategies have attracted extensive attention in the field of oncotherapy.However,current strategies are unable to differentiate well between...
关键词：nitric oxide nitric oxide synthetase nanozyme MITOCHONDRIA specific cancer therapy 
Synergetic lethal energy depletion initiated by cancer cell membrane camouflaged nano-inhibitor for cancer therapy被引量：1
《Nano Research》2022年第4期3422-3433,共12页Fudan Dong Qikun Jiang Lingxiao Li Tian Liu Shiyi Zuo Lin Gao Mengna Fang Yanlin Gao Bingjun Sun Cong Luo Zhonggui He Jin Sun 
This work was financially supported by National Natural Science Foundation of China(No.81773656);Liaoning Revitalization Talents Program(No.XLYC1808017);Shenyang Youth Science and Technology Innovation Talents Program(No.RC190454);National Postdoctoral Foundation of China(No.2021M693868).
Mitochondrial bioenergy plays a vital role in the occurrence and development of cancer.Although strategies to impede mitochondrial energy supply have been rapidly developed,the anticancer efficacy is still far from sa...
关键词：synergetic lethality energy depletion mitochondria-targeting mitochondrial oxidative phosphorylation GLYCOLYSIS 
In vitro study of enhanced photodynamic cancer cell killing effect by nanometer-thick gold nanosheets被引量：4
《Nano Research》2020年第12期3217-3223,共7页Ziyi Zhang Dalong Ni Fei Wang Xin Yin Shreya Goel Lazarus NGerman Yizhan Wang Jun Li Weibo Cai Xudong Wang 
This work was supported by the Army Research Office(No.W911NF-16-1-0198);the National Science Foundation(No.DMR-1709025);National Institutes of Health(Nos.R01EB0213360,1R21EB027857,and P30CA014520);Diffraction data was collected at ChemMatCARS Sector 15,which is principally supported by the Divisions of Chemistry and Materials Research,National Science Foundation,under grant number NSF/CHE-1834750;Use of the Advanced Photon Source,an Office of Science User Facility operated for the U.S.Department of Energy(DOE)Office of Science by Argonne National Laboratory,was supported by the U.S.DOE(No.DEAC02-06CH11357).
Photodynamic therapy(PDT)by near-infrared(NIR)irradiation is a promising technique for treating various cancers.Here,we reported the development of free-standing wafer-scale Au nanosheets(NSs)that exhibited an impress...
关键词：gold nanosheet ionic layer epitaxy surface plasmon photodynamic effect cancer therapy 
Fabrication of ultrathin Zn（OH）2 nanosheets as drug carriers被引量：1
《Nano Research》2016年第8期2520-2530,共11页Ren Cai Dan Yang Jin Wu Liqin Zhang Cuichen Wu Xigao Chen Yanyue Wang Shuo Wan Fengwei HOU Qingyu Yan Weihong Tan 
The authors are grateful to Dr. Kathryn Williams for her critical comments during the preparation of this manuscript. This work is supported by grants awarded by the National Institutes of Health （No. GM079359 and CA133086）. This work is also supported by the National Basic Research Program of China （No. 2011CB911000）, National Natural Science Foundation of China （Nos. 21221003 and 21327009） and China National Instrumentation Program （No. 2011YQ03012412）.
Ultrathin two-dimensional （2D） porous Zn（OH）2 nanosheets （PNs） were fabricated by means of one-dimensional Cu nanowires as backbones. The PNs have thickness of approximately 3.8 nm and pore size of 4-10 nm. To f...
关键词：APTAMER porous Zn（OH）2 nanosheets cancer cell cell-targeted delivery 
Near-infrared light-activated cancer cell targeting and drug delivery with aptamer-modified nanostructures被引量：4
《Nano Research》2016年第1期139-148,共10页Yu Yang Jingjing Liu Xiaoqi Sun Liangzhu Feng Wenwen Zhu Zhuang Liu Meiwan Chen 
This work was partially supported by the National Natural Science Foundation of China （Nos. 51222203 and 51132006）, the National Basic Research Program of China （Nos. 2011CB911002 and 2012CB932601）, a Jiangsu Natural Science Fund for Distinguished Young Scholars, the Macao Science and Technology Develop- ment Fund （No. 062/2013/A2） and the Research Fund of the University of Macao （Nos. MYRG2014-00033- ICMS-QRCM and MRGOO4/CMW/2014/ICMS）.
Stimuli-activated targeted delivery systems for highly accurate treatment of tumors have received considerable attention in recent years. Herein, we reveal a light-activable cancer-targeting strategy that uses a compl...
关键词：near-infrared（NIR）-activable drug delivery APTAMER gold nanorods single-walled carbonnanotubes 
Highly Fluorescent Dye-Doped Silica Nanoparticles Increase Flow Cytometry Sensitivity for Cancer Cell Monitoring被引量：3
《Nano Research》2009年第6期448-461,共14页M.-Carmen Estévez Meghan B.OʼDonoghue Xiaolan Chen Weihong Tan 
by the NIH National Cancer Institute,R21CA122648,ONR N00014-07-1-0982,and the State of Florida Center of Excellence.M.-C.E.acknowledges fi nancial support from the Department d’Universitats,Recerca i Societat de la Informacióde la Generalitat de Catalunya,Spain.
Early and accurate diagnosis and treatment of cancer depend on rapid,sensitive,and selective detection of tumor cells.Current diagnosis of cancers,especially leukemia,relies on histology and fl ow cytometry using sing...
关键词：Silica nanoparticle flow cytometry APTAMER cell detection polyethylene glycol fl uorophore 
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