supported by the National Key Research and Development Program of China;Nos.2021YFC2 701800 and 2021YFC2 701805 (to QY);Open Research Fund of State Key Laboratory of Genetic Engineering;Fudan University;No.SKLGE-21 19 (to TXH and QY)
In Alzheimer’s disease,the transporter P-glycoprotein is responsible for the clearance of amyloid-βin the brain.Amyloid-βcorrelates with the sphingomyelin metabolism,and sphingomyelin participates in the regulation...
This work was in part supported by the Plough Center for Sterile Drug Delivery Solution at the University of Tennessee Health Science Center(to SK).
Traumatic brain injury is a sudden trauma or blow on the head,and severe traumatic brain injury is a major cause of death and disability worldwide.The acute and chronic consequences following traumatic brain injury ca...
supported by the Technological Project of Science and Technology Department of Henan Province in China,No.122102310205;the National Natural Science Foundation of China,No.30771140,31070952,U1204311
Prenatal alcohol exposure, especially during early pregnancy, can lead to fetal alcohol syndrome. The pharmacological and toxicological mechanisms of ethanol are related to the effects of ceramide In this study, we es...
the National Nat-ural Science Foundation of Chi-na, No. 30472238; the Grantfrom Bureau of Public Health ofShanghai City, No. 05JC14053;Shanghai Key Subjects Con-struction Program, No. T0302
BACKGROUND: Ceramide galactosyltransferase (CGT) protein and mRNA expression defect can cause the abnormal morphology and slowing conduction velocity of peripheral nerve. Morphologic change and functional disorder ...