CHOLINERGIC

作品数：112被引量：321H指数：9
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相关作者：张麟胡大一李静张均田段文贞更多>>
相关机构：北京大学首都医科大学附属北京朝阳医院中国医学科学院北京协和医学院中国中医研究院更多>>
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Dopaminergic-cholinergic imbalance in movement disorders: a role for the novel striatal dopamine D2-muscarinic acetylcholine M1 receptor heteromer
《Neural Regeneration Research》2021年第7期1406-1408,共3页RenéA.J.Crans Francisco Ciruela 
supported by the Fonds Wetenschappelijk Onderzoek(FWOSBO, Grant number 140028);Ministerio de Ciencia, Innovación y Universidades-Agencia Estatal de Investigación/FEDER(Grant number SAF2017-87349-R);Generalitat de Catalunya(Grant numbers 2017 SGR1604 and 2017 SGR595);Fundació la Marató de TV3(grant number 20152031);supported by an FWO Travel Grant for a Long Stay Abroad(grant number V420718N);an EMBO Short-Term Fellowship(grant number 6735)。
The striatum is the primary input structure of the basal ganglia, which participates in motivational and goaldirected behaviors(Pisani et al., 2007).In physiological conditions, local cholinergic interneurons(ChIs) an...
关键词：al. DOPAMINE DOPAMINE 
Pharmacological Modulation of Vagal Nerve Activity in Cardiovascular Diseases被引量：7
《Neuroscience Bulletin》2019年第1期156-166,共11页Longzhu Liu Ming Zhao Xiaojiang Yu Weijin Zang 
supported by grants from the National Natural Science Foundation of China(81770293 and 81473203)
Cardiovascular diseases are life-threatening illnesses with high morbidity and mortality. Suppressed vagal(parasympathetic) activity and increased sympathetic activity are involved in these diseases. Currently, pharma...
关键词：Cardiovascular disease CHOLINERGIC DRUGS MUSCARINIC RECEPTOR a7-nACh RECEPTOR VAGUS nerve Vagomimetic DRUGS 
Allosteric modulation of cholinergic system:Potential approach to treating cognitive deficits of schizophrenia被引量：3
《World Journal of Pharmacology》2016年第1期32-43,共12页Shaun Hopper Madhara Udawela Elizabeth Scarr Brian Dean 
Schizophrenia is a psychiatric disorder affecting approximately 1% of the population worldwide and is characterised by the presence of positive and negative symptoms and cognitive deficits. Whilst current therapeutics...
关键词：Central nervous system ANTIPSYCHOTIC ALLOSTERIC CHOLINERGIC SCHIZOPHRENIA MUTAGENESIS Cognition MUSCARINIC 
M1 muscarinic acetylcholine receptor in Alzheimer's disease被引量：10
《Neuroscience Bulletin》2014年第2期295-307,共13页Shangtong Jiang Yanfang Li Cuilin Zhang Yingjun Zhao Guojun Bu Huaxi Xu Yun-Wu Zhang 
supported by grants from the National Institutes of Health,USA(R01AG038710,R01AG021173,R01AG044420 and R01NS046673);the Alzheimer’s Association,the National Natural Science Foundation of China(91332112,81225008 and 81161120496);Fundamental Research Funds for the Central Universities of China;the Fok Ying Tung Education Foundation
The degeneration of cholinergic neurons and cholinergic hypofunction are pathologies associated with Alzheimer＇s disease （AD）. Muscarinic acetylcholine receptors （mAChRs） mediate acetylcholine-induced neurotransm...
关键词：AGONIST Alzheimer＇s disease AMYLOID cholinergic hypofunction M1 muscarinic acetylcholinereceptor tau 
Muscarinic cholinergic regulation of L-type calcium channel in heart of embryonic mice at different developmental stages被引量：1
《Acta Pharmacologica Sinica》2004年第11期1450-1457,共8页Hua-minLIANG MingTANG Chang-jinLIU Hong-yanLUO Yuan-longSONG Xin-wuHU Jiao-yaXI Lin-linGAO BinNIE Su-yunLI Ling-lingLAI JuergenHESCHELER 
Project supported by the National Natural Science Foundation of China(No30070279).
AIM: To investigate the muscarinic regulation of L-type calcium current (ICa_L) during development. METHODS: The whole cell patch-clamp technique was used to record ICa_L in mice embryonic cardiomyocytes at different ...
关键词：8-bromo cyclic adenosine monophosphate calcium channels cell differentiation embryo and fetal development FORSKOLIN HEART MICE patch-clamp techniques muscarinic receptors 
Autoantibodies against the myocardial β_1-adrenergic and M_2-muscarinic receptors in patients with congestive heart failure被引量：3
《Chinese Medical Journal》2002年第8期1127-1131,共5页张麟 胡大一 李静 吴雅峰 刘秀兰 杨新春 
ThestudywassupportedbyBeijingScience&TechnologyGrant(No 95 5 5 10 0 70 0 )
Objective To determine whether autoantibodies against β 1-adrenergic and M 2-muscarinic receptors are related to patients with congestive heart failure (CHF).Methods Both synthetic peptides corresponding to amino...
关键词：congestive heart failure . adrenrgic receptors . beta-1. cholinergic  receptors 
Autoantibodies against the myocardial β<sub>1</sub>-adrenergic and M<sub>2</sub>-muscarinic receptors in patients with congestive heart failure
《Chinese Medical Journal》2002年第8期7-11,144-145,共页张麟 胡大一 李静 吴雅峰 刘秀兰 杨新春 
Objective To determine whether autoantibodies against β 1-adrenergic and M 2-muscarinic receptors are related to patients with congestive heart failure (CHF).Methods Both synthetic peptides corresponding to amino...
关键词：congestive heart failure · adrenrgic receptors · beta-1· cholinergic  receptors 
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