CHROMATOGRAPHIC

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A new quantitative structure-retention relationship model for predicting chromatographic retention time of oligonucleotides被引量：2
《Science China Chemistry》2011年第7期1064-1071,共8页ZHAO Wei LIANG GuiZhao CHEN YuZhen YANG Li 
supported by the National Natural Science Foundation of China (10901169);National 111 Programme of Introducing Talents of Discipline to Universities (0507111106);Innovation Ability Training Foundation of Chongqing University (CDCX008);Innovative Group Program for Graduates of Chongqing University,Science;Innovation Fund (200711C1A0010260)
An integrated approach is proposed to predict the chromatographic retention time of oligonucleotides based on quantitative structure-retention relationships （QSRR） models. First, the primary base sequences of oligon...
关键词：OLIGONUCLEOTIDE quantitative structure-retention relationship scores of generalized base properties auto cross covariance genetic algorithm support vector machine 
Recent advances in proteolysis and peptide/protein separation by chromatographic strategies被引量：2
《Science China Chemistry》2010年第4期685-694,共10页ZHANG XiangMin1, LIU BaoHong1, ZHANG LiHua2, ZOU HanFa2, CAO Jing1, GAO MingXia1, TANG Jia1, LIU Yun1, YANG PengYuan1 & ZHANG YuKui2 1Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China 2Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China 
support from the Major State Basie Research Development Program (Grant No. 2007CB914100);the National Natural Science Foundation of China (Grant Nos. 20875016 & 20735005);Shanghai Projects (Grant Nos. 08DZ2293601 & B109)
This review gives a broad glance on the progress of recent advances on proteolysis and peptide/protein separation by chroma-tographic strategies in the past ten years, covering the main research in these areas especia...
关键词：PROTEOLYSIS ENZYMATIC DIGESTION CHROMATOGRAPHIC separation PEPTIDE enrichment mass SPECTROMETRY 
Chemometrics and modernization of traditional Chinese medicine被引量：3
《Science China Chemistry》2008年第8期718-728,共11页LIANG YiZeng YI LunZhao XU QingSong 
Supported by the National Natural Science Foundation China (Grant Nos. 20475066 and 10771217);the International Cooperation Project on Traditional Chinese Medicines of Ministry of Science and Technology of China (Grant Nos. 2006DFA41090 and 2007DFA40680)
Development of chromatographic fingerprinting and its related chemometric methods in the research of quality control of traditional Chinese medicines(TCMs) are discussed. The quality control methods for guarantying th...
关键词：MODERNIZATION of TRADITIONAL Chinese MEDICINE CHEMOMETRICS CHROMATOGRAPHIC fingerprinting QUALITY control 
Microdialysis-liquid chromatographic study on competitive binding of drugs to protein
《Science China Chemistry》1997年第6期643-649,共7页汪海林 邹汉法 张玉奎 
Project supported by the Chinese Academy of Sciences;the National Natural Science Foundation of China
A new method to determine the interaction between drug and protein has been developed by utilizing the technique of microdialysis sampling with the ketoprofen and the human serum albumin (HSA) as the model of drug and...
关键词：MICRODIALYSIS sampling LIQUID CHROMATOGRAPHY COMPETITIVE binding drug-protein interaction 
THE UNIFIED FORM OF RETENTION EQUATION OF CHROMATOGRAPHY
《Science China Chemistry》1991年第1期13-25,共13页戴朝政 卢佩章 李浩春 
The unified form of retention equation of chromatography is suggested by adoptingstatistical thermodynamics and lattice theory. According to different conditions, the retentionformulas of GC, LC and SFC can be obtaine...
关键词：CHROMATOGRAPHIC RETENTION EQUATION CHROMATOGRAPHIC RETENTION RULE gas CHROMATOGRAPHY liquid CHROMATOGRAPHY SUPERCRITICAL fluid CHROMATOGRAPHY 
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