云南高校图书馆联盟文献共享服务平台- CINACALCET

CINACALCET: 作品数：12被引量：15H指数：2; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：李涛彭小勇杨光明刘良明洪侃更多>>; 相关机构：第三军医大学大坪医院南京医科大学安徽医科大学第一附属医院华东理工大学更多>>; 相关期刊：《临床医学工程》《Acta Pharmacologica Sinica》《中国医药导刊》《中华医学信息导报》更多>>; 相关基金：国家自然科学基金教育部留学回国人员科研启动基金更多>>

Determination and Validation of HPTLC Method for Cinacalcet Hydrochloride: 《American Journal of Analytical Chemistry》2019年第2期55-64,共10页Swetha Kamatham Ciddi Veeresham; Cinacalcet Hydrochloride (CIN) is a new calcimimetic agent indicated for the use in hypercalcemia. The present work is aimed at development and validation of a novel and simple high-performance thin-layer chromatograp...; 关键词：CINACALCET HYDROCHLORIDE HPTLC METHOD VALIDATION DENSITOMETRY Forced Degradation

Progress in the Clinical Application of Cinacalcet in the Treatment of Secondary Hyperthyroidism: 《临床医学工程》2017年第S1期52-54,共3页Yueling ZHU Shengling HUANG Shuang Cui Lianghong YIN Taksui Wong Xiangnan DONG Bing YAN Baozhang GUAN Bo HU Fanna LIU Yingyan LI Shanshan LI Xin CHEN Berthold Hocher Wolfgang Pommer; Guangdong Obers Blood Purification Aca demi cian Work station(2013B090400004);Guangdong University blood purifica tion technology and Engineering Re search Center(GCZX-A1104);Guangzhou en trepreneurial leader talent/LCY201215;Guangdong Provincial Center for clinical engineer ing of blood purification(507204531040); Secondary hyperthyroidism(SHPT)is a common complication of maintenance hemodialysis(MHD).In China the prevalence of chronic kidney disease(CKD)is 10.8%and there are about 0.2 million patients treated with maintenance ...; 关键词：CINACALCET Maintenance hemodialysis(MHD) Secondary hyperthyroidism(SHPT) Calcium sensing receptor(CaSR)

The study of calcitriol,cinacalcet combined with nursing intervention effect of SHPT, calcium, phosphorus metabolism and parathyroid hormone on MHD patients: 《Journal of Hainan Medical University》2017年第6期45-47,共3页Le Chen Xiao-Yun Wu; Objective:To investigate calcitriol, cinacalcet plus comprehensive intervention on maintenance hemodialysis (MHD) patients with secondary hyperparathyroidism (SHPT) calcium (Ca), phosphorus (P) metabolism and parathyr...; 关键词：CALCITRIOL CINACALCET NURSING intervention MHD SHPT CALCIUM Phosphorus Parathyroid hormone

Cinacalcet ameliorates aortic calcification in uremic rats via suppression of endothelial-to-mesenchymal transition被引量：10: 《Acta Pharmacologica Sinica》2016年第11期1423-1431,共9页Min WU Ri-ning TANG Hong LIU Ming-ming PAN Bi-cheng LIU; These studies were supported by grants from the National Natural Science Foundation of China （81130010, 81470997, 31571186, and 81500545）, Natural Science Foundation of Jiangsu Province （BK20150640） and Clinic Research Center of Jiangsu Province （BL2014080）.; Aim： Experimental studies found that cinacalcet （ClNA） markedly attenuated vascular calcification in uremic rats, but its underlying mechanisms are still largely unknown. Recent evidence have demonstrated that endo...; 关键词：CINACALCET UREMIA aortic calcification endothelial cells parathyroid hormone endothelial-to-mesenchymal transition

CaSR在大鼠血管收缩/舒张反应性调节中的作用被引量：3: 《局解手术学杂志》2016年第9期629-632,共4页彭小勇李涛刘良明杨光明; 国家自然科学基金(81571886);军队医学科技青年培育项目(13QNP118);教育部留学回国人员科研启动基金(2014); 目的研究钙敏感性受体(Ca SR)激动剂对大鼠肠系膜动脉收缩和舒张反应性的影响、以及内皮在其中的作用。方法采用内皮完整和内皮去除的大鼠肠系膜动脉,观察Ca SR特异性激动剂cinacalcet对血管基础张力和预收缩的血管张力的影响、以及不...; 关键词：钙敏感性受体 CINACALCET 内皮收缩反应性舒张反应性

Before the Jury Is out on Cinacalcet’s Cardiovascular Effects in Hemodialysis Patients: Is Troponin a Missing Link?: 《Open Journal of Nephrology》2014年第1期47-53,共7页Samra Abouchacra Ahmed Chaaban Mohammad Budruddin Fares Chedid Mohamad Hakim Mohamad Ahmed Nicole Gebran Farida Marzouki Muhy Eddin Hassan Faiz Al Abbacheyi; Raised levels of the cardiac biomarker, Troponin I, are frequently encountered in hemodialysis patients and appear to be prognostic indicators for cardiovascular risk. Though evidence suggests that control of secondar...; 关键词：Calcimimetics Secondary Hyperparathyroidism Parathyroid Hormone CINACALCET Chronic Kidney DISEASE Cardio VASCULAR DISEASE End Stage Renal DISEASE TROPONIN I C-Reactive Protein PARATHYROIDECTOMY Acute Coronary Syndrome Peripheral VASCULAR DISEASE Atherogenesis Myocardial Infraction

cinacalcet在原发性甲状旁腺功能亢进症治疗中的研究进展被引量：1: 《医学研究杂志》2012年第2期171-174,共4页卞坤娟洪侃; 原发性甲状旁腺功能亢进症（hyperparathyroidism Primary,PHPT）是甲状旁腺分泌过多的甲状旁腺素（parathyroid hormone,PTH）引起的钙磷比例失调和骨代谢紊乱的一种全身性疾病,主要病因为甲状旁腺腺瘤、腺癌和甲状旁腺增生。治疗首选...; 关键词：原发性甲状旁腺功能亢进症 CINACALCET 治疗甲状旁腺切除术甲状旁腺腺瘤甲状旁腺增生甲状旁腺素全身性疾病

钙敏感受体在甲状旁腺功能亢进中的作用被引量：1: 《国际外科学杂志》2011年第5期339-342,共4页王晓巍陈智勇朱化刚; 钙敏感受体（CaSR）主要表达于甲状旁腺细胞和肾小管上皮细胞，它可通过细胞内信号传导通路改变甲状旁腺激素（PTH）的分泌和。肾小管对电解质和水的处理，调节体内钙平衡，同时CaSR也参与了骨重塑的过程。其遗传性的基因异常可引起各...; 关键词：甲状旁腺功能亢进症钙敏感受体自身抗体基因突变 CINACALCET

cinacalcet可影响透析患者钙-甲状旁腺激素曲线: 《中华医学信息导报》2008年第18期6-6,共1页; 甲状旁腺-钙曲线受到甲状旁腺激素水平的调控，甲状旁腺分泌甲状旁腺激素来调控细胞外钙离子浓度。甲状旁腺功能亢进的患者和对照组相比该曲线右移，提示甲状旁腺细胞对钙离子的敏感性下降。因此设想增加钙敏感受体表达来增加甲状旁腺...; 关键词：甲状旁腺激素钙离子浓度 CINACALCET 曲线透析患者甲状旁腺功能亢进甲状旁腺细胞激素水平

通用名药与药物经济学--04093 Cinacalcet的成本效益“合理”: 《国外药讯》2007年第4期48-48,共1页李燕燕（摘）; 根据在第43届欧洲肾脏学会和欧洲透析与移植学会会议上公开的成本分析，Cinacalcet（Ⅰ）是行血液透析的晚期肾病（ESRD）患者减少失控的骨矿物质代谢的“合理的成本效益治疗选择”。第二项研究证实，以对治疗反应的相同成本计，（Ⅰ）...; 关键词：成本效益药物经济学通用名药骨矿物质代谢血液透析治疗反应标准护理成本分析

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