云南高校图书馆联盟文献共享服务平台- COLORECTAL

COLORECTAL_CANCER: 作品数：2101被引量：8336H指数：33; 导出分析报告; 相关作者：王书奎马中华李娟彭鹏周晶更多>>; 相关机构：江苏省人民医院重庆医科大学南方医科大学南方医院中山大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>

Global pattern and trends of colorectal cancer survival: a systematic review of population-based registration data被引量：5: 《Cancer Biology & Medicine》2022年第2期175-186,共12页Yufei Jiang Huiyun Yuan Zhuoying Li Xiaowei Ji Qiuming Shen Jiayi Tuo Jinghao Bi Honglan Li Yongbing Xiang; This work was supported by funding from the National Key Project of Research and Development Program of China(Grant No.2016YFC1302503);the National Key Basic Research Program of China“973 Program”(Grant No.2015CB554000).; This review will describe the global patterns and trends of colorectal cancer survival,using data from the population-based studies or cancer registration.We performed a systematic search of China National Knowledge I...; 关键词：Colorectal cancer survival rate PROGNOSIS population-based study cancer registration

Targeting tumor endothelial hyperglycolysis enhances immunotherapy through remodeling tumor microenvironment被引量：4: 《Acta Pharmaceutica Sinica B》2022年第4期1825-1839,共15页Yunlong Shan Qi Ni Qixiang Zhang Mengying Zhang Bin Wei Lingge Cheng Chongjin Zhong Xinyu Wang Qingqing Wang Jiali Liu Jingwei Zhang Jingjing Wu Guangji Wang Fang Zhou; This research was supported by National Natural Science Foundation of China(Nos.82073929,82104184,82103318,and 82173887);China Postdoctoral Science Foundation(No.2020M671662);the Jiangsu postdoctoral grant program(Nos.2020Z354 and 2020Z152,China);Leading Technology Foundation Research Project of Jiangsu Province(No.BK20192005,China);National Basic Research Program of China(973 Program,No.2017YFA0205400);the Project of State Key Laboratory of Natural Medicines,China Pharmaceutical University(No.SKLNMZZ202001,China);“Double First-Class”University project(No.CPU2018GF01,China);Jiangsu Province“333”project(China).; Vascular abnormality is a hallmark of most solid tumors and facilitates immune evasion.Targeting the abnormal metabolism of tumor endothelial cells(TECs)may provide an opportunity to improve the outcome of immunothera...; 关键词：Endothelial glycolysis GAPDH Osimertinib Normalized glycolysis Immunometabolism Colorectal cancer Tumor microenvironment IMMUNOTHERAPY

Upregulated insulin receptor tyrosine kinase substrate promotes the proliferation of colorectal cancer cells via the bFGF/AKT signaling pathway: 《Gastroenterology Report》2021年第2期166-175,I0002,I0003,共12页Song Wang Zheng Liu Yi-Ming Ma Xu Guan Zheng Jiang Peng Sun En-Rui Liu Yu-Kun Zhang Hong-Ying Wang Xi-Shan Wang; supported by the National Program Project for Precision Medicine in National Research and Development Plan of China [No.2016YFC0905300];National Natural Science Foundation of China [No.81572930];National Key Research and Development Program of the Ministry of Science and Technology of China [No.2016YFC0905303];Beijing Science and Technology Program [No.D171100002617004].; Background:Some recent studies on insulin receptor tyrosine kinase substrate(IRTKS)have focused more on its functions in diseases.However,there is a lack of research on the role of IRTKS in carcinomas and its mechanis...; 关键词：colorectal cancer PROLIFERATION IRTKS AKT BFGF

Prognostic scoring system for synchronous brain metastasis at diagnosis of colorectal cancer: A population-based study被引量：2: 《World Journal of Gastrointestinal Oncology》2020年第2期195-204,共10页Ji-Chuan Quan Xu Guan Chen-Xi Ma Zheng Liu Ming Yang Zhi-Xun Zhao Peng Sun Meng Zhuang Song Wang Zheng Jiang Xi-Shan Wang; Supported by National Key Research and Development Program of the Ministry of Science and Technology of China,No.2016YFC0905303,2016YFC0905300;Beijing Science and Technology Program,No.D171100002617004; BACKGROUND Brain metastasis(BM)from colorectal cancer(CRC)is rarely encountered clinically,and its prognosis has not been fully evaluated.AIM To construct a scoring system and accurately predict the survival of patien...; 关键词：Colorectal cancer Brain metastasis SURVIVAL Prognosis factors Scoring system SYNCHRONOUS

Bcl-3 promotes Wnt signaling by maintaining the acetylation ofβ-catenin at lysine 49 in colorectal cancer被引量：3: 《Signal Transduction and Targeted Therapy》2020年第1期1913-1924,共12页Xi Chen Chen Wang Yuhang Jiang Qi Wang Yu Tao Haohao Zhang Yongxu Zhao Yiming Hu Cuifeng Li Deji Ye Dandan Liu Wenxia Jiang Eugene Y.Chin Sheng Chen Yongzhong Liu Mingliang Wang Sanhong Liu Xiaoren Zhang; funded by the National Program on Key Research(2018YFA0107500,2016YFC1302400);National Basic Research Program(2014CB541904 and 2014CB943600);National Natural Science Foundation of China(91742113,31570902,81702950,81772798,91949102 and 81771752);Natural Science Foundation of Shanghai(14ZR1426300,18ZR1424400,18ZR1446400,18431902700);China Postdoctoral Science Foundation(2017M611633);Guangzhou Key Medical Discipline Construction Project Fund.; Wnt/β-catenin signaling plays a critical role in colorectal cancer(CRC)tumorigenesis and the homeostasis of colorectal cancer stem cells(CSCs),but its molecular mechanism remains unclear.B-cell lymphoma 3(Bcl-3),a me...; 关键词：COLORECTAL HOMEOSTASIS cancer

The Composition of Colonic Commensal Bacteria According to Anatomical Localization in Colorectal Cancer被引量：4: 《Engineering》2017年第1期90-97,共8页Liuyang Zhao Xiang Zhang Tao Zuo Jun Yu; This project was supported by RGC-GRF Hong l（ong （766613, 14106145）, the National Basic Research Program of China （2013CB531401）, the National Natural Science Foundation of China （NSFC）（81201963, 81372600）, the Shenzhen Municipal Science and Technology R＆D fund （JCYJ20120619152326450）, and the Shenzhen Virtual University Park Support Scheme to CUHK Shenzhen Research Institute.; Colorectal cancer （CRC） is a multistage disease resulting from complex factors, including genetic mutations, epigenetic changes, chronic inflammation, diet, and lifestyle. Recent accumulating evidence suggests that ...; 关键词：Microbiota Colorectal cancer Luminal commensal bacteria Translocation Biomarker

iTRAQ-based quantitative analysis of cancer-derived secretory proteome reveals TPM2 as a potential diagnostic biomarker of colorectal cancer被引量：1: 《Frontiers of Medicine》2016年第3期278-285,共8页Yiming Ma Ting Xiao Quan Xu Xinxin Shao Hongying Wang; This work was financially supported by National Basic Research Program of China （973 Program, No. 2011CB910700） and National Natural Science Foundation of China （No. 81201966）.; Colorectal cancer （CRC） is a leading cause of cancer-related deaths worldwide. We aimed to find novel molecules as potential biomarkers for the early diagnosis of CRC. A serum-free conditioned medium was successfull...; 关键词：ITRAQ SECRETOME colorectal cancer TPM2

Remarkably Reduced Expression of FoxO3a in Metaplastic Colorectum, Primary Colorectal Cancer and Liver Metastasis被引量：1: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2013年第2期205-211,共7页何乐亚魏欣杜蕾刘鹭徐丰闵江李川陶德定陈佺胡俊波龚建平; supported by the grants from 973 Program Project from Ministry of Science and Technology in China(No.2009CB521802);National Natural Science Foundation of China(No.30872472,No.30973496,and No.30800569); The forkhead family members of transcription factors （FoxOs） are expected to be potential cancer-related drug targets and thus are being extremely studied recently. In the present study, FoxO3a, one major member of ...; 关键词：FOXO3A colorectal cancer transcription factor cell cycle arrest target therapy

Epigenetic changes in colorectal cancer被引量：7: 《Chinese Journal of Cancer》2013年第1期21-30,共10页Yan Jia Mingzhou Guo; supported by grants from the National Basic Research Program(973Program No.2012CB934002,2010CB912802);National Key Scientific instrument Special Programme of China(Grant No.2011YQ03013405);National Science Foundation of China(Grant No.81121004,81071953); Epigenetic changes frequently occur in human colorectal cancer.Genomic global hypomethylation,gene promoter region hypermethylation,histone modifications,and alteration of miRNA patterns are major epigenetic changes i...; 关键词：遗传变化大肠癌表观 MICRORNA 甲基化剂组蛋白修饰基因启动子区非编码RNA

SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are prognosis-related in colorectal cancer被引量：20: 《World Journal of Gastroenterology》2011年第15期2028-2036,共9页Shu-Jing Yu Jie-Kai Yu Wei-Ting Ge Han-Guang Hu Ying Yuan Shu Zheng; Supported by Grants from the Major State Basic Research Development Program of China, 973 Program No. 2004CB518707;the Zhejiang Provincial Natural Science Foundation of China,No. R2090353;the Fundamental Research Funds for the Central Universities, No. KYJD09007; AIM: To investigate the expression of markers that are correlated with the prognosis of colorectal cancer (CRC) patients. METHODS: One hundred and fifty-six CRC patientswere followed up for more than 3 years after rad...; 关键词：Colorectal cancer Prognosis SPARCL1 P53 BIOINFORMATICS

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