supported by the Construction Project of Liaoning Provincial Key Laboratory;China(2022JH13/10200026);Fund of the Affiliated Xiangshan Hospital of Wenzhou Medical University;Wenzhou Traditional Chinese Medicine Hospital of Zhejiang Chinese Medical University;Wenzhou;Department of Hepatobiliary Surgery;The First Affiliated Hospital of Wenzhou Medical University;Wenzhou Institute University of Chinese Academy of Sciences。
Current challenges and opportunities for liquid biopsies.Liquid biopsies serve as an indispensable clinical diagnostic tool when traditional biopsies are difficult to obtain or yield inadequate samples for genetic mon...
supported by the National Natural Science Foundation of China (32070643, 32130051, 31961133009);Science and Technology Commission of Shanghai Municipality (20JC1411500);the ECNU Public Platform for Innovation (011);the Instruments Sharing Platform of the School of Life Sciences,East China Normal University;supported by the US National Institutes of Health (NIH) grant 1RO1CA251698-01;Cancer Prevention and Research Institute of Texas (CPRIT) grant RP190077。
MYC is an oncogenic transcription factor with a novel role in enhancing global transcription when overexpressed. However, how MYC promotes global transcription remains controversial. Here, we used a series of MYC muta...
Outstanding Graduate Entering Laboratory Project of College of Fisheries,Guangdong Ocean University;National Natural Science Foundation of China(32073015);Natural Science Foundation of Guangdong Province(2021A1515011078);Special Fund for Science and Technology Innovation Strategy of Guangdong Province(Undergraduate Science and Technology Innovation Cultivation)(pdjh2021b0239);Undergraduate Innovation and Entrepreneurship Training Program of Guangdong Ocean University(CXXL2021122);Undergraduate Innovation Team of Guangdong Ocean University(CCTD-201802).
[Objectives]To amplify the DNA-binding response regulator PhoP in Vibrio alginolyticus and analyze its sequence characteristics and subunit structure.[Methods]According to the sequence of the DNA-binding response regu...
Supported by the National Natural Science Foundation of China (No. 21763022)。
A new complex[Cu_(1.5)(tfc)_(3)(H_(2)O)_(4)]·3H_(2)O (1,Htfc=4-(trifluoro-methyl) nicotinic acid) has been synthesized and characterized by X-ray single-crystal diffraction,elemental analysis,IR spectra and thermogra...
Supported by the Scientific Research Fund of Hunan Provincial Education Department of China(No.19C0279);Functional Metal-organic Compounds of Hunan Science and Technology Innovation Team。
supported by Biotechnology and Biological Sciences Research Council grant BB/M007405/1(to M.J.C.and L.-O.P.);the Dutch Technology Foundation STW and Earth and Life Sciences ALW(to E.J.S.,O.C.A.S.,and A.G.);VICI project no.865.14.003(to F.L.W.T.)(Netherlands Organization for Scientific Research).
Plant NLR proteins enable the immune systemto recognize and respond to pathogen attack.An early consequence of immune activation is transcriptional reprogramming.SomeNLRs have been shownto act in the nucleus and inter...
supported by the Natural Science Foundation of Hubei Province (2018CFB323)。
Two novel macrocyclic Schiff base complexes[LnL(PhCOO)(CH3OH)](ClO4)2·(CH3OH)2(Ln=Ho,1;Ln=Er,2),in which L denotes the macrocyclic ligand,were synthesized via condensation of 2,6-diformyl-4-methyl-phenol and 1,3-diam...
supported by the National Natural Science Foundation of China(31572106 and 31622049).
DNA-binding one zinc-finger(Dof)proteins constitute a family of transcription factors with a highly conserved Dof domain that contains a C2C2 zinc-finger motif.Although several studies have demonstrated that Dof prote...
Cd(Ⅱ), Co(Ⅱ), Cu(Ⅱ) and Zn(Ⅱ) complexes(1~4) based on 2-(2-pyridyl)benzimidazole(pbm) and 4,4'-oxybisbenzoic acid(H2odc) were synthesized. The formulas of these complexes are [Cd(pbm)(odc)2](1), [Co(pbm)(odc)2](2)...