DNA-BINDING

作品数:62被引量:206H指数:6
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相关领域:生物学更多>>
相关作者:贾磊李飞飞王浴生杨春蕾王跃琦更多>>
相关机构:兰州大学北京大学河南理工大学四川大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金湖南省教育厅科研基金更多>>
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Glow in the dark fluid:Nanoparticles and DNA-binding antibodies as priming agents for liquid biopsies
《Science Bulletin》2024年第22期3474-3477,共4页Yi Zhang Wanlu Zhang Yinghao Zhi Hongwei Sun Min Wu Yongye Huang 
supported by the Construction Project of Liaoning Provincial Key Laboratory;China(2022JH13/10200026);Fund of the Affiliated Xiangshan Hospital of Wenzhou Medical University;Wenzhou Traditional Chinese Medicine Hospital of Zhejiang Chinese Medical University;Wenzhou;Department of Hepatobiliary Surgery;The First Affiliated Hospital of Wenzhou Medical University;Wenzhou Institute University of Chinese Academy of Sciences。
Current challenges and opportunities for liquid biopsies.Liquid biopsies serve as an indispensable clinical diagnostic tool when traditional biopsies are difficult to obtain or yield inadequate samples for genetic mon...
关键词:ANTIBODIES clinical LIQUID 
MYC promotes global transcription in part by controlling P-TEFb complex formation via DNA-binding independent inhibition of CDK9 SUMOylation被引量:1
《Science China(Life Sciences)》2023年第9期2167-2184,共18页Qingqing Guan Zhaosu Chen Fang Yu Lingling Liu Yuanyong Huang Gang Wei Cheng-Ming Chiang Jiemin Wong Jiwen Li 
supported by the National Natural Science Foundation of China (32070643, 32130051, 31961133009);Science and Technology Commission of Shanghai Municipality (20JC1411500);the ECNU Public Platform for Innovation (011);the Instruments Sharing Platform of the School of Life Sciences,East China Normal University;supported by the US National Institutes of Health (NIH) grant 1RO1CA251698-01;Cancer Prevention and Research Institute of Texas (CPRIT) grant RP190077。
MYC is an oncogenic transcription factor with a novel role in enhancing global transcription when overexpressed. However, how MYC promotes global transcription remains controversial. Here, we used a series of MYC muta...
关键词:MYC global transcription P-TEFB CDK9 SUMOYLATION cell transformation 
Bioinformatics Analysis of DNA-binding Response Regulator PhoP in Vibrio alginolyticus
《Asian Agricultural Research》2022年第3期42-46,61,共6页Yifan WU Junlin WANG Fuyuan ZENG Weijie ZHANG Xing XIAO Huanying PANG 
Outstanding Graduate Entering Laboratory Project of College of Fisheries,Guangdong Ocean University;National Natural Science Foundation of China(32073015);Natural Science Foundation of Guangdong Province(2021A1515011078);Special Fund for Science and Technology Innovation Strategy of Guangdong Province(Undergraduate Science and Technology Innovation Cultivation)(pdjh2021b0239);Undergraduate Innovation and Entrepreneurship Training Program of Guangdong Ocean University(CXXL2021122);Undergraduate Innovation Team of Guangdong Ocean University(CCTD-201802).
[Objectives]To amplify the DNA-binding response regulator PhoP in Vibrio alginolyticus and analyze its sequence characteristics and subunit structure.[Methods]According to the sequence of the DNA-binding response regu...
关键词:Vibrio alginolyticus Gene cloning PHOP Bioinformatics analysis 
Syntheses,Crystal Structures and DNA-Binding Properties of Zn(Ⅱ)and Mn(Ⅱ)Complexes Based on Imidazole Derivatives and Carboxylic Acid
《Chinese Journal of Structural Chemistry》2022年第3期260-269,I0014,共11页GUAN Hui-Chao SONG Xiao-Tong LIU Gui-Bao YUE Shu-Mei 
Complexes[Zn(pbm)(5-hip)_(3)](1),[Zn(pbm)(5-nip)3](2),[Mn(pbm)(H_(3)btc)_(2)(H_(2)O)](3)and[Mn(pbm)(5-nip)_(3)](4),where H2HIPA=5-hydroxyisophthalic acid,H2nip=5-nitroisophthalic acid,H3btc=tri-mesic acid and pbm(pyri...
关键词:single-crystal structures spectroscopy CT-DNA binding 2-(2-pyridyl)benzimidazole 
Synthesis,Crystal Structure and DNA-Binding Property of a New Cu(Ⅱ) Complex Based on 4-(Trifluoro-methyl)nicotinic Acid
《Chinese Journal of Structural Chemistry》2022年第2期57-63,I0008,共8页SHAN Feng-Lin SONG Huan GAO Xue-Zhi LI Bing MA Xiao-Xia 
Supported by the National Natural Science Foundation of China (No. 21763022)。
A new complex[Cu_(1.5)(tfc)_(3)(H_(2)O)_(4)]·3H_(2)O (1,Htfc=4-(trifluoro-methyl) nicotinic acid) has been synthesized and characterized by X-ray single-crystal diffraction,elemental analysis,IR spectra and thermogra...
关键词:4-(trifluoro-methyl)nicotinic acid crystal structure DNA 
Syntheses,Crystal Structures,Anticancer Activities and DNA-Binding Properties of the Dibutyltin Complexes Based on Benzoin Aroyl Hydrazone
《Chinese Journal of Structural Chemistry》2022年第2期105-113,I0010,共10页JIANG Wu-Jiu TAN Yu-Jun MAN Jia-Tai TAN Yu-Xing 
Supported by the Scientific Research Fund of Hunan Provincial Education Department of China(No.19C0279);Functional Metal-organic Compounds of Hunan Science and Technology Innovation Team。
Dibutyltin benzoin benzoyl hydrazone complex Ⅰ[C_(6)H_(5)(O)C=N-N=C(Ph)CH(Ph)O]_(2)[(n-Bu)_(2)Sn]_(2)and dibutyltin benzoin salicyl hydrazone complex Ⅱ[2-(OH)-C_(6)H_(4)(O)C=N-N=C(Ph)CH(Ph)O]_(2)[(n-Bu)_(2)Sn]_(2)we...
关键词:DIBUTYLTIN complex synthesis crystal structure DNA 
A DNA-Binding Bromodomain-Containing Protein Interacts with and Reduces Rx1-Mediated Immune Response to Potato Virus X
《Plant Communications》2020年第4期101-114,共14页Octavina C.A.Sukarta Philip D.Townsend Alexander Llewelyn Christopher H.Dixon Erik J.Slootweg Lars-Olof Pålsson Frank L.W.Takken Aska Goverse Martin J.Cann 
supported by Biotechnology and Biological Sciences Research Council grant BB/M007405/1(to M.J.C.and L.-O.P.);the Dutch Technology Foundation STW and Earth and Life Sciences ALW(to E.J.S.,O.C.A.S.,and A.G.);VICI project no.865.14.003(to F.L.W.T.)(Netherlands Organization for Scientific Research).
Plant NLR proteins enable the immune systemto recognize and respond to pathogen attack.An early consequence of immune activation is transcriptional reprogramming.SomeNLRs have been shownto act in the nucleus and inter...
关键词:cellular immune response DNA-binding protein host-pathogen interaction plant biochemistry plant defense plant virus 
Synthesis, Crystal Structures, DNA Cleavage and DNA-binding Studies of Ho(Ⅲ) and Er(Ⅲ)Complexes Based on Macrocyclic Schiff Base
《Chinese Journal of Structural Chemistry》2020年第6期1103-1111,共9页WANG Xiao-Bo YU Xiao-Qi HU Xue-Lei 
supported by the Natural Science Foundation of Hubei Province (2018CFB323)。
Two novel macrocyclic Schiff base complexes[LnL(PhCOO)(CH3OH)](ClO4)2·(CH3OH)2(Ln=Ho,1;Ln=Er,2),in which L denotes the macrocyclic ligand,were synthesized via condensation of 2,6-diformyl-4-methyl-phenol and 1,3-diam...
关键词:macrocyclic Schiff base crystal structure CT-DNA pBR 322 fluorescence spectrum 
The apple DNA-binding one zinc-finger protein MdDof54 promotes drought resistance被引量:12
《Horticulture Research》2020年第1期235-249,共15页Pengxiang Chen Mingjia Yan Lei Li Jieqiang He Shuangxi Zhou Zhongxing Li Chundong Niu Chana Bao Fang Zhi Fengwang Ma Qingmei Guan 
supported by the National Natural Science Foundation of China(31572106 and 31622049).
DNA-binding one zinc-finger(Dof)proteins constitute a family of transcription factors with a highly conserved Dof domain that contains a C2C2 zinc-finger motif.Although several studies have demonstrated that Dof prote...
关键词:DROUGHT resistance EXPRESSING 
Syntheses, Crystal Structures and DNA-binding Properties of Cd(Ⅱ), Co(Ⅱ), Cu(Ⅱ) and Zn(Ⅱ) Complexes Containing Imidazolium Derivatives
《Chinese Journal of Structural Chemistry》2020年第2期356-367,188,共13页LI Yu-Han YANG Yu GUAN Hui-Chao ZHANG Min XU Lin-Lin YUE Shu-Mei 
Cd(Ⅱ), Co(Ⅱ), Cu(Ⅱ) and Zn(Ⅱ) complexes(1~4) based on 2-(2-pyridyl)benzimidazole(pbm) and 4,4'-oxybisbenzoic acid(H2odc) were synthesized. The formulas of these complexes are [Cd(pbm)(odc)2](1), [Co(pbm)(odc)2](2)...
关键词:2-(2-pyridyl)benzimidazole crystal structure CT-DNA binding 
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