DNA_DAMAGE

作品数：397被引量：1149H指数：14
导出分析报告
相关作者：黄百渠张瑜刘松陆军孙晋渊更多>>
相关机构：东北师范大学首都师范大学上海交通大学医学院附属新华医院浙江林学院更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金中国博士后科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
选择条件：
  • 期刊=Science China（Life Sciences）x
共 条 记 录，以下是1-6
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Engineering biomimetic nanosystem targeting multiple tumor radioresistance hallmarks for enhanced radiotherapy
《Science China(Life Sciences)》2024年第7期1398-1412,共15页Shuxiang Wang Hongmei Cao Cui-Cui Zhao Qian Wang Dianyu Wang Jinjian Liu Lijun Yang Jianfeng Liu 
supported by the National Science Fund for Distinguished Young Scholars of China(82225026);the National Natural Science Foundation of China(82172082);CAMS Innovation Fund for Medical Sciences(2021-I2M-1-042,2023-I2M-QJ-016)。
Tumor cells establish a robust self-defense system characterized by hypoxia,antioxidant overexpression,DNA damage repair,and so forth to resist radiotherapy.Targeting one of these features is insufficient to overcome ...
关键词：biomimetic nanosystem hypoxia alleviation glutathione consumption oxidative stress amplification DNA damage fixation RADIOSENSITIZATION 
The oxidative DNA damage response： A review of research undertaken with Tsinghua and Xiangya students at the University of Pittsburgh被引量：1
《Science China(Life Sciences)》2017年第10期1077-1080,共4页S.Levine Luxi Sun Rong Tan Ying Gao Lu Yang Hao Chen Yaqun Teng Li Lan 
supported in part by grants from the National Institutes of Health GM118833 to LL;project used the UPMC Hillman Cancer Center Cytometry Facility, supported in part by National Institutes of Health P30CA047904
Endogenous stress and exogenous toxicants(chemicals and UV light) alter genetic information either directly or indirectly through the production of reactive oxygen species(ROS), thereby driving genomic instability in ...
关键词：DNA damage CHROMATIN TELOMERE DNA repair 
Small RNAs:Emerging key players in DNA double-strand break repair被引量：1
《Science China(Life Sciences)》2013年第10期933-936,共4页BA ZhaoQing QI YiJun 
supported in part by China National Funds for Distinguished Young Scientists(31225015);National Key Scientific Research Program of China(2012CB910900)to Qi YiJun
DNA double-strand break （DSB） is the most deleterious form of DNA damage and poses great threat to genome stability. Eu- karyotes have evolved complex mechanisms to repair DSBs through coordinated actions of protein...
关键词：DNA damage small RNAs diRNA DICER ARGONAUTE 
The CXXC finger 5 protein is required for DNA damage-induced p53 activation
《Science China(Life Sciences)》2009年第6期528-538,共11页ZHANG Min1,WANG RuiPeng1,WANG YanYi 2,DIAO FeiCi1,LU Fei1,GAO Dong1,CHEN DanYing 1,ZHAI ZhongHe1 & SHU HongBing2 1 College of Life Sciences,Peking University,Beijing 100871,China 2 College of Life Sciences,Wuhan University,Wuhan 430072,China 
Supported by National Basic Research Program of China (Grant No. 2006CB504301);National High Technology Research and Development Program of China (Grant No. 2006AA02A306);National Natural Science Foundation of China (Grant Nos. 30630019 and 30570959)
The tumor suppressor p53 is a critical component of the DNA damage response pathway that induces a set of genes responsible for cell cycle arrest,senescence,apoptosis,and DNA repair.The ataxia te-langiectasia mutated ...
关键词：P53 ATM DNA damage APOPTOSIS 
Fast repair of purine deoxynucleotide radical cations by rutin and quercetin被引量：3
《Science China(Life Sciences)》2001年第6期610-617,共8页赵晨阳 石益民 王文锋 贾忠建 姚思德 范波涛 郑荣梁 
This work was supported partly by the National Natural Science Foundation of China (Grant No.39870902), the Doctoral Programme of the Education Ministry of China, and the China-France Cooperative Research Sponsored by the Education Ministry of China.
Repair effects of rutin and quercetin on purine deoxynucleotide radical cations were studied using pulse radiolysis technique. On electron pulse irradiation of N2 saturated deoxynucleotide aqueous solution containing ...
关键词：DNA damage deoxynucleotide radical cation REPAIR electron transfer RUTIN quercetin. 
Mechanism of p53 downstream effectors p21 and Gadd45 in DNA damage surveillance
《Science China(Life Sciences)》1999年第4期427-434,共8页孟祥兵 董燕 孙志贤 
Project supported by the National Natural Science Foundation of China (Grant No. 39700038).
Both p21( WAF1/CIP1) and Gadd45 were activated in a p53-dependent manner in MCF-7 cells after being exposed to ionizing radiation. In order to investigate their roles in DNA damage surveillance, p21as/MCF-7 cells stab...
关键词：P21 GADD45 G1 ARREST DNA repair apoptosis. 
全选清除导出
共1页<1>
检索报告 对象比较 聚类工具 使用帮助 返回顶部