DOUBLECORTIN

作品数:35被引量:114H指数:5
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相关领域:医药卫生生物学更多>>
相关作者:李鑫梁森胡长林谭新杰蔡文琴更多>>
相关机构:广西医科大学第三军医大学中国医科大学重庆医科大学附属第二医院更多>>
相关期刊:《神经解剖学杂志》《华中科技大学学报(医学版)》《Frontiers in Biology》《中华神经外科杂志》更多>>
相关基金:国家自然科学基金北京市自然科学基金广东省自然科学基金北京市科技新星计划更多>>
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Grafts of hydrogel-embedded electrically stimulated subventricular stem cells into the stroke cavity improves functional recovery of mice
《Neural Regeneration Research》2026年第2期695-703,共9页Andreea-Mihaela Cercel Ianis KS Boboc Roxana Surugiu Thorsten R.Doeppner Dirk M.Hermann Bogdan Catalin Andrei Gresita Aurel Popa-Wagner 
supported by European Union Funding Programme,PNRR,No.760058(to DMH)and the UEFISCDI Project,No.PN-III-P4-ID-PCE-2020-059(to APW).#。
The major aim of stroke therapy is to stimulate brain repair and improve behavioral recovery after cerebral ischemia.One option is to stimulate endogenous neurogenesis in the subventricular zone and direct the newly f...
关键词:ANXA3 behavioral recovery DOUBLECORTIN electrical stimulation Mash1 NESTIN STROKE subventricular neural stem cells supportive hydrogel vascular cell adhesion molecule 1 
宫颈癌组织Semaphorin3A、Doublecortin样激酶-1表达与上皮间质转化的关系及意义
《中华实用诊断与治疗杂志》2024年第1期57-61,共5页石小芳 王俊青 王朝霞 武玉巧 
山西省重点研发计划项目(201903D321145)。
目的 观察宫颈癌组织Semaphorin3A、Doublecortin样激酶-1(DCLK1)表达变化,探讨其与上皮间质转化的关系及对预后的影响。方法 2019年1月—2022年1月临汾市人民医院行手术治疗的宫颈癌患者100例,取手术切除宫颈癌组织及癌旁组织,采用实...
关键词:宫颈癌 Semaphorin3A Doublecortin样激酶-1 上皮间质转化 预后 
Psilocybin facilitates fear extinction in mice by promoting hippocampal neuroplasticity被引量:4
《Chinese Medical Journal》2023年第24期2983-2992,共10页Yingjie Du Yunfeng Li Xiangting Zhao Yishan Yao Bin Wang Liming Zhang Guyan Wang 
supported by grants from the STI2030-Major Projects(Nos.2021ZD0200900 and 2021ZD0202000);National Natural Science Foundation of China(Nos.81773708,82270411 and 81970344);Beijing Hospitals Authority's Ascent Plan(No.DFL20220203);Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support(No.ZYLX202103)
Background:Posttraumatic stress disorder(PTSD)and depression are highly comorbid.Psilocybin exerts substantial therapeutic effects on depression by promoting neuroplasticity.Fear extinction is a key process in the mec...
关键词:Brain-derived neurotrophic factor BROMODEOXYURIDINE Depression Doublecortin domain proteins Extinction psychological FREEZING Hippocampus Neuronal plasticity Psilocybin Stress disorders post-traumatic 
Neuroprotective effects of meloxicam on transient brain ischemia in rats:the two faces of anti-inflammatory treatments被引量:4
《Neural Regeneration Research》2023年第9期1961-1967,共7页Irene Fernández Ugidos Paloma González-Rodríguez María Santos-Galdiano Enrique Font-Belmonte Berta Anuncibay-Soto Diego Pérez-Rodríguez JoséManuel Gonzalo-Orden Arsenio Fernández-López 
supported by MINECO and FEDER funds:ref CPP2021-008855 and RTC-2015-4094-1,Junta de Castilla y León ref.LE025P1 7;Neural Therapies SL;ref.NTDev-01 (all to AFL and JMGO)。
The inflammato ry response plays an important role in neuroprotection and regeneration after ischemic insult.The use of non-ste roidal anti-inflammatory drugs has been a matter of debate as to whether they have benefi...
关键词:ANTI-INFLAMMATORIES ASTROCYTE axonal sprouting cylinder test DOUBLECORTIN focal brain ischemia glial scar inflammation neuroprotection new neuron generation transient stroke 
No DCX-positive neurogenesis in the cerebral cortex of the adult primate被引量:2
《Neural Regeneration Research》2020年第7期1290-1299,共10页Ruo-Xu Liu Jie Ma Bin Wang Tian Tian Ning Guo Shao-Jun Liu 
supported by the National Natural Science Foundation of China(Key Program),No.30430310(to SJL);the State Key Laboratories Development Program of China,No.SKLP-K201401(to SJL)
Whether endogenous neurogenesis occurs in the adult cortex remains controversial.An increasing number of reports suggest that doublecortin(DCX)-positive neurogenesis persists in the adult primate cortex,attracting eno...
关键词:adult neurogenesis antigen neutralization autofluorescence cross reaction cross reactivity DOUBLECORTIN NEOCORTEX NEUN non-specificity PRIMATES tissue adsorption 
Effects of CXCR7-neutralizing antibody on neurogenesis in the hippocampal dentate gyrus and cognitive function in the chronic phase of cerebral ischemia被引量:3
《Neural Regeneration Research》2020年第6期1079-1085,共7页Bing-Chao Dong Mei-Xuan Li Xiao-Yin Wang Xi Cheng Yu Wang Ting Xiao Jukka Jolkkonen Chuan-Sheng Zhao Shan-Shan Zhao 
supported by the National Natural Science Foundation of China,No.81401002(to SSZ)
Stromal cell-derived factor-1 and its receptor CXCR4 are essential regulators of the neurogenesis that occurs in the adult hippocampal dentate gyrus.However,the effects of CXCR7,a new atypical receptor of stromal cell...
关键词:cerebral ischemia cognitive function CXCR7 dendritic development DENTATE GYRUS DOUBLECORTIN NEUROGENESIS NEUTRALIZING antibody stroke stromal cell-derived factor-1 
Korean red ginseng promotes hippocampal neurogenesis in mice被引量:4
《Neural Regeneration Research》2020年第5期887-893,共7页Sun Ryu Hyongjun Jeon Hee-Young Kim Sungtae Koo Seungtae Kim 
supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Education(No.NRF-2016R1D1A3B03930920 to SK);the MSIP(No.NRF-2014R1A5A2009936 to SK)
Neurogenesis in the adult hippocampus plays a major role in cognitive ability of animals including learning and memory.Korean red ginseng (KRG) has long been known as a medicinal herb with the potential to improve lea...
关键词:BROMODEOXYURIDINE cerebral dopamine NEUROTROPHIC FACTOR ciliary NEUROTROPHIC FACTOR DOUBLECORTIN GINSENG hippocampus Korean RED GINSENG learning memory neurogenesis proliferating cell nuclear antigen RED GINSENG 
Beta-nerve growth factor gene therapy alleviates pyridoxine-induced neuropathic damage by increasing doublecortin and tyrosine kinase A in the dorsal root ganglion被引量:2
《Neural Regeneration Research》2020年第1期162-168,共7页Hyun-Kee Cho Woosuk Kim Kwon-Young Lee Jin-Ok Ahn Jung Hoon Choi In Koo Hwang Jin-Young Chung 
supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT&Future Planning(No.NRF-2017R1A1A1A05000762);Cooperative Research Program for Agriculture Science and Technology Development,Rural Development Administration,Republic of Korea(No.PJ01395602; both to JYC)
Beta-nerve growth factor(β-NGF) is known to be a major leading cause of neuronal plasticity. To identify the possible action mechanisms of β-NGF gene therapy for sciatic nerve recovery, experimental dogs were random...
关键词:β-nerve growth factor βIII-tubulin DOUBLECORTIN gene therapy neuron-glial antigen 2 neuropathy PYRIDOXINE 
幼犬脑组织Doublecortin的表达观测被引量:1
《系统医学》2018年第22期16-19,共4页李明 武志兵 杨永强 王文成 侯燕红 刘学敏 
长治医学院科研启动基金项目(QDZ201521;QDZ201633)
目的通过观测Doublecortin(微管相关蛋白)在幼犬脑的不同组织部位的表达,探讨哺乳动物出生早期的神经发育机制。方法 2016年7月—2017年4月,由长治医学院实验动物中心提供哺乳动物幼犬4只,出生后给予正常饲养15 d,后多聚甲醛灌注液灌注...
关键词:DOUBLECORTIN 脑皮层 齿状回 室管膜下区 
Extract of Ginkgo biloba promotes neuronal regeneration in the hippocampus after exposure to acrylamide被引量:5
《Neural Regeneration Research》2017年第8期1287-1293,共7页Wei-ling Huang Yu-xin Ma Yu-bao Fan Sheng-min Lai Hong-qing Liu Jing Liu Li Luo Guo-ying Li Su-min Tian 
supported by the Natural Science Foundation of Guangdong Province of China,No.2014A030310455;the Pearl River S&T Nova Program Foundation of Guangzhou City of China,No.201710010002
Previous studies have demonstrated a neuroprotective effect of extract of Ginkgo biloba against neuronal damage, but have mainly focused on antioxidation of extract of Ginkgo biloba. To date, limited studies have dete...
关键词:nerve regeneration brain injury extrat of Ginkgo biloba ACRYLAMIDE DOUBLECORTIN brain-derived neurotrophic factor growthassociated protein-43 NEURONS damage HIPPOCAMPUS mice neural regeneration 
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