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作品数：76被引量：210H指数：7
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相关领域：医药卫生生物学更多>>
相关作者：胡孝素敬保迁马莹卜玲毅王雅静更多>>
相关机构：上海交通大学川北医学院四川大学福州总医院更多>>
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相关基金：国家自然科学基金广东省自然科学基金国家重点基础研究发展计划World Health Organization更多>>
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A Study of Epileptogenic Foci Localization Algorithm Based on Automatic Detection of Comprehensive Feature HFOs and RF-LR
《Chinese Journal of Electronics》2025年第1期338-349,共12页Yuxiao Du Gaoming Li 
supported by the National Natural Science Foundation of China(Grant Nos.61640213 and 61976059)。
Studies have shown that fast ripples of 250–500 Hz in epileptic electroencephalography(EEG)signals are more pathological and closer to the epileptogenic focus itself compared to ripples of 80–250 Hz.However,artifact...
关键词：High-frequency oscillation Multivariate features Random forest Logistic regression 
Flexible,high-density,laminated ECoG electrode array for high spatiotemporal resolution foci diagnostic localization of refractory epilepsy被引量：2
《Bio-Design and Manufacturing》2024年第4期388-398,共11页Yafeng Liu Zhouheng Wang Yang Jiao Ying Chen Guangyuan Xu Yinji Ma Xue Feng 
support of the National Natural Science Foundation of China(Nos.U20A6001,12002190,11972207,and 11921002);the Fundamental Research Funds for the Central Universities,China(No.SWUKQ22029);the Chongqing Natural Science Foundation of China(No.CSTB2022NSCQ-MSX1635).
High spatiotemporal resolution brain electrical signals are critical for basic neuroscience research and high-precision focus diagnostic localization,as the spatial scale of some pathologic signals is at the submillim...
关键词：Electrocorticogram(ECoG)electrode EPILEPSY High density High resolution Laminated structure 
Phase-modulated multi-foci microscopy for rapid 3D imaging
《Photonics Research》2024年第7期1548-1555,共8页WEIQI WANG LI GONG ZHIWEI HUANG 
National Medical Research Council (NMRC),Singapore (A-0009502-01-00, A-8001143-00-00);Merlion Fund (R397-000-356-133);Academic Research Fund(AcRF) from the Ministry of Education (MOE),Singapore(Tier 1 (R397-000-334-114),Tier 1 (R397-000-371-114,R397-000-378-114),Tier 2 (A-8000117-01-00))。
3D imaging technology is pivotal in monitoring the functional dynamics and morphological alterations in living cells and tissues.However,conventional volumetric imaging associated with mechanical z-scanning encounters...
关键词：alterations SCATTERED BEADS 
Application and progress of artificial intelligence technology in the segmentation of hyperreflective foci in OCT images for ophthalmic disease research
《International Journal of Ophthalmology(English edition)》2024年第6期1138-1143,共6页Jia-Ning Ying Hu Li Yan-Yan Zhang Wen-Die Li Quan-Yong Yi 
Supported by Zhejiang Provincial Natural Science Foundation of China(No.LGF22H120013);the Ningbo Natural Science Foundation(No.2023J209,No.2021J023);Ningbo Medical Science and Technology Project(No.2021Y57);Ningbo Yinzhou District Agricultural Community Development Science and Technology Project(No.2022AS022);Ningbo Eye Hospital Scientific Technology Plan Project and Talent Introduction Start Subject(No.2022RC001).
With the advancement of retinal imaging,hyperreflective foci(HRF)on optical coherence tomography(OCT)images have gained significant attention as potential biological biomarkers for retinal neuroinflammation.However,th...
关键词：artificial intelligence deep learning hyperreflective foci image analysis 
Algorithm of automatic identification of diabetic retinopathy foci based on ultra-widefield scanning laser ophthalmoscopy
《International Journal of Ophthalmology(English edition)》2024年第4期610-615,共6页Jie Wang Su-Zhen Wang Xiao-Lin Qin Meng Chen Heng-Ming Zhang Xin Liu Meng-Jun Xiang Jian-Bin Hu Hai-Yu Huang Chang-Jun Lan 
Supported by Hunan Provincial Science and Technology Department Clinical Medical Technology Innovation Guidance Project(No.2021SK50103)。
AIM:To propose an algorithm for automatic detection of diabetic retinopathy(DR)lesions based on ultra-widefield scanning laser ophthalmoscopy(SLO).METHODS:The algorithm utilized the FasterRCNN(Faster Regions with CNN ...
关键词：diabetic retinopathy ultra-widefield scanning laser ophthalmoscopy intelligent diagnosis system 
Aflibercept combined with triamcinolone acetonide in the treatment of diabetic macular edema:optical coherence tomography and optical coherence tomography angiography
《International Journal of Ophthalmology(English edition)》2024年第4期670-675,共6页De-Shuang Li Hong-Xia Liao Chuan-He Zhang Jian-Guo Huang Wei Chen Jing-Lin Zhang Bo Qin 
Supported by the Natural Science Foundation of Guangdong Province,China(No.2022A1515010742);Hunan Provincial Natural Science Foundation of China(No.2023JJ70039);Scientific Research Program of Xiangjiang Philanthropy Foundation.
AIM:To analyze the relationship between optical coherence tomography(OCT)and OCT angiography(OCTA)imaging in patients with diabetic macular edema(DME)who are treated with a combination of aflibercept and triamcinolone...
关键词：diabetic macular edema optical coherence tomography optical coherence tomography angiography hyperreflective foci subretinal fluid foveal avascular zone AFLIBERCEPT 
Phosphorylation Promotes the Accumulation of PERIOD Protein Foci
《Research》2024年第1期59-69,共11页Mengna Li Shujing Li Luoying Zhang 
grants from the Natural Science Foundation of China(3193002i and 32022035);the Ministry of Science and Technology of China STI 2030-Major Projects(2021ZD0203200-02)to L.Z.
Circadian clock drives the 24-h rhythm in our behavior and physiology.The molecular clock consists of a series of transcriptional/translational feedback loops operated by a number of clock genes.A very recent study re...
关键词：CONCLUSION SEPARATED TRANSLATIONAL 
The presence of foci of Rickettsia conorii infection in China
《Infectious Medicine》2023年第4期334-337,共4页Nannan Xu Hui Liu Chunmei Qu Sai Wen Wenlu Zou Caiyun Chang Gang Wang 
China is not considered as an endemic area of Rickettsia conorii,so there is no routine clinical way to diagnose this infection.This study aims to determine whether 2 febrile patients who had a tick bite in East China...
关键词：Rickettsia conorii Human infection China 
Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy被引量：39
《Neural Regeneration Research》2023年第5期976-982,共7页Lei Tang Guo-Tong Xu Jing-Fa Zhang 
supported by the National Natural Science Foundation of China,No. 82171062 (to JFZ)。
Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients. Many clinical features observed in diabetic retinopathy, such as ...
关键词：anti-inflammation therapy anti-vascular endothelial growth factor diabetic retinopathy hyperreflectivity foci INFLAMMATION inflammatory cells inflammatory cytokines leukostasis MICROGLIA Müller cells 
Compact multi-foci metalens spectrometer被引量：8
《Light(Science & Applications)》2023年第5期905-914,共10页Ruoxing Wang Muhammad Afnan Ansari Hammad Ahmed Yan Li Wenfeng Cai Yanjun Liu Songtao Li Jianlong Liu Li Li Xianzhong Chen 
funded by the Engineering and Physical Sciences Research Council(EP/P029892/1);the Leverhulme Trust(RPG-2021-145);the Royal Society International Exchanges(IES\R3\193046);the support from the National Natural Science Foundation of China(62205106).
A lightweight and portable spectrometer is desirable for miniaturization and integration.The unprecedented capability of optical metasurfaces has shown much promise to perform such a task.We propose and experimentally...
关键词：SPECTRA UNIQUENESS ILLUMINATION 
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