GENOMIC

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Wheat genomic study for genetic improvement of traits in China被引量：26
《Science China(Life Sciences)》2022年第9期1718-1775,共58页Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong 
This work was supported by the National Natural Science Foundation of China(31788103,31970529,32125030,31921005,31961143013,32072660);the Key Research and Development Program of Ministry of Science and Technology of China(2021YFF1000200);the Strategic Priority Research Program of Chinese Academy of Sciences(XDA24010202).
Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestic...
关键词：WHEAT GENOMICS genetic improvement China 
Genomic features underlying the evolutionary transitions of Apibacter to honey bee gut symbionts被引量：3
《Insect Science》2022年第1期259-275,共17页Wenjun Zhang Xue Zhang Qinzhi Su Min Tang Hao Zheng Xin Zhou 
The work was funded by the Program of Ministry of Science and Technology of China(2018FY100403);National Natural Science Foundation of China(31772493).
The gut bacteria of honey bee recognized as a mutualistic partner with the insect host might have originated from a free-living or parasitic lifestyle. However, little is known about the genomic features underlying th...
关键词：Apibacter spp. comparative genomics evolution gut microbiome honey bee nitrate respiratory reduction 
TEAseq-based identification of 35,696 Dissociation insertional mutations facilitates functional genomic studies in maize被引量：2
《Journal of Genetics and Genomics》2021年第11期961-971,共11页Mingjie Lyu Huafeng Liu Joram Kiriga Waititu Ying Sun Huan Wang Junjie Fu Yanhui Chen Jun Liu Lixia Ku Xiliu Cheng 
the Ministry of Science and Technology of China(2016YFD0101000 and 2016YFD0101001);the Natural Science Foundation of China(31901595).
In plants,transposable element(TE)-triggered mutants are important resources for functional genomic studies.However,conventional approaches for genome-wide identification of TE insertion sites are costly and laborious...
关键词：MAIZE Zea mays Insertion identification Ds transposon Mutant library Next-generation sequencing Functional genomics 
Enhancing Genetic Gain through Genomic Selection: From Livestock to Plants被引量：14
《Plant Communications》2020年第1期4-24,共21页Yunbi Xu Xiaogang Liu Junjie Fu Hongwu Wang Jiankang Wang Changling Huang Boddupalli MPrasanna Michael SOlsen Guoying Wang Aimin Zhang 
The research involved in this report was supported by the National Key Research and Development Program of China(2016YFD0101803);the National Key Basic Research Program of China(2014 CB138206);the Agricultural Science and Technology Innovation Program of CAAS,and Fundamental Research Funds for Central Non-Profit of Institute of Crop Sciences,CAAS(1610092016124);Research activities of CIMMYT staff have been supported by the Bill and Melinda Gates Foundation and the CGIAR Research Program MAIZE.
Although long-term genetic gain has been achieved through increasing use of modern breeding methods and technologies,the rate of genetic gain needs to be accelerated to meet humanity’s demand for agricultural product...
关键词：genomic selection genetic gain open-source breeding genomic prediction molecular marker livestock breeding 
Genomic characterization of an atypical enteropathogenic Escherichia coli strain isolated in Fujian province, China
《Science China(Life Sciences)》2019年第9期1261-1263,共3页Aiping Chen Yongjun Zhang Linglan Wang 
supported by the following grants: Initiative Projects of Medical Sciences in Fujian (2011-CXB-19);Natural Science Foundation of Fujian (2014J01282 and 2016Y0011);Ministry of Science and Technology of China (2017ZX10103008)
Dear Editor,Enteropathogenic Escherichia coli (EPEC) is recognized as the leading cause of infantile diarrhea in developing countries.Since 1996,EPEC has been divided into typical and atypical strains,based on the pre...
关键词：EAF HOST range ASYMPTOMATIC 
iCatch:a new strategy for capturing large DNA fragments using homing endonucleases
《Acta Biochimica et Biophysica Sinica》2019年第1期97-103,共7页Jingman Wang Anrui Lu Jiakun Liu Weiren Huang Jin Wang Zhiming Cai Guoping Zhao 
the grants from the National Key Basic Research Program of China (973 Program)(No.2014CB745201);the National Natural Science Foundation of China (No.81772737);the Strategic Priority Research Program of the Chinese Academy of Sciences (No.XDB19040200);the International Cooperation Program of the Chinese Academy of Sciences (No.153D31KYSB20170121);the National Science Foundation Projects of Guangdong Province (No.2017B030301015);the Shenzhen Municipal Government of China (Nos.JCYJ20170413161749433 and JSGG20160301161836370);the Sanming Project of Shenzhen Health and Family Planning Commission (Nos.SZSM201412018 and SZSM201512037);and the High Level University Medical Discipline Construction (No.2016031638).
Natural genetic materials contain many biosynthetic gene clusters encoding potentially valuable natural products,many of which can be used directly without codon optimization or other manipulations.With the developmen...
关键词：GENOMIC CAPTURE HOMING ENDONUCLEASE BIOLOGICAL part HETEROLOGOUS expression 
Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs被引量：8
《Zoological Research》2018年第6期424-430,共7页Yang Yang Adeniyi C.Adeola Hai-Bing Xie Ya-Ping Zhang 
supported by grants from the National Natural Science Foundation of China(31472000);National 973 Program of China(2013CB835203);Animal Branch of the Germplasm Bank of Wild Species,Chinese Academy of Sciences(Large Research Infrastructure Funding)
The Bama Xiang pig （BMX） Chinese indigenous breed is a famous early-maturing with a two-end black coat To uncover the genetic basis of the BMX phenotype, we conducted comparative genomic analyses between BMX and Eas...
关键词：Puberty Bama Xiang pig PITUITARY Differentially expressed genes 
Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine(5hmC)被引量：2
《Genomics, Proteomics & Bioinformatics》2018年第3期172-186,共15页Yajing Chu Zhigang Zhao David Wayne Sant Ganqian Zhu Sarah M. Greenblatt Lin Liu Jinhuan Wang Zeng Cao Jeanette Cheng Tho Shi Chen Xiaochen Liu Peng Zhang Jaroslaw P. Maciejewski Stephen Nimer Gaofeng Wang Weiping Yuan Feng-Chun Yang Mingjiang Xu 
supported by grants from the National Institutes of Health (Grant No. CA172408 to MX and FCY, Grant No. HL112294 to MX);the Leukemia & Lymphoma Society (LLS) (SCOR program to SN, FCY, and MX; translational grant to SN);University of Miami Sylvester Comprehensive Cancer Center (SCCC to MX and FCY), the United States;supported by the Ministry of Science and Technology of China (Grant Nos. 2017YFA0103402to WY);National Natural Science Foundation of China (Grant Nos. 81629001 to MX, 81670102 to ZZ, 81600136 to YC, and 81421002 to WY);CAMS Innovation Fund for Medical Sciences (Grant Nos. 2017-I2M-3-015 to WY and 2016-I2M-1-017 to YC);Tianjin Application Foundation and Advanced Technology Research Program (Grant Nos. 16JCYBJC25200 to ZZ and 17JCQNJC09800 to YC);SKLEH-Pilot Research Grand (Grant No. ZK16-3 to ZZ);Peking Union Medical College Youth Fund (Grant No. 3332016092 to YC), China
As a dioxygenase. Ten-Eleven Translocation 2 （TET2） catalyzes subsequent steps of 5-methylcytosine （5mC） oxidation. TET2 plays a critical role in the self-renewal, proliferation, and differentiation of hei-natopoi...
关键词：Tet2 5hmC MACROPHAGE OSTEOCLAST Runxl 
Genomic alterations and precise medicine of esophageal squamous cell carcinoma
《Journal of Bio-X Research》2018年第1期7-11,共5页Qionghua Cui Chen Wu Dongxin Lin 
This work was supported by National Key Basic Research and Development Program(973 project,grants No.2015CB553901 to DL and 2013CB910301 to CW);National Key R&D Program(grant No.2016YFC1302100 to DL);CAMS Innovation Fund for Medical Sciences(Grants No.2016-12M-3-019 to DL and 2016-12M-4-002 to CW).
Human cancer is a complex disease caused by the interaction of multiple genes and environmental factors.It is known that environmental factors such as smoking,drinking,and food carcinogens are implicated in the develo...
关键词：esophageal cancer genomic alteration precise medicine 
Transforming bacterial disease surveillance and investigation using whole-genome sequence to probe the trace被引量：13
《Frontiers of Medicine》2018年第1期23-33,共11页Biao Kan Haijian Zhou Pengcheng Du Wen Zhang Xin Lu Tian Qin Jianguo Xu 
Two decades have passed since the first bacterial whole-genome sequencing, which provides new opportunity for microbial genome. Consequently, considerable genetic diversity encoded by bacterial genomes and among the s...
关键词：genome sequencing genomic epidemiotogy bacteria SURVEILLANCE infectious diseases 
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