supported by the National Natural Science Foundation of China(Nos.U22A20160,82221003,81991505,82201123);China Postdoctoral Science Foundation(2022M720290,2021M700279);Hubei Provincial Key Laboratory of Oral and Maxillofacial Development and Regeneration Open Fund(2022kqhm004).
Bone tissue renewal can be enhanced through co-transplantation of bone mesenchymal stem cells(BMSCs)and vascular endothelial cells(ECs).However,there are apparent limitations in stem cell-based therapy which hinder it...
This work was supported by the Key Clinical Projects of Peking University Third Hospital[grant number BYSYZD2019041].
Osteoporosis,fracture,large-scale craniofacial defects and osteonecrosis are hot topics and are still underdiagnosed and undertreated in the clinic.It is urgent to understand the molecular mechanisms corresponding to ...
This work was supported by the Major Research Plan of National Natural Science Foundation of China[No.91649204];the National Key Research and Development Program of China[2016YFC1100100];the Scientific Research Training Program for Young Talents from Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,National Natural Science Foundation of China(82002333)。
Tissue specificity,a key factor in the decellularized tissue matrix(DTM),has shown bioactive functionalities in tuning cell fate-e.g.,the differentiation of mesenchymal stem cells.Notably,cell fate is also determined ...
This work was financially supported by National key R&D Program of China(2018YFC1105402,2017YFC1104402,2017YFC1105000);National Natural Science Foundation of China(31700823,U1801252,31771027);Natural Science Foundation of Guangdong Province of China(2020A1515011354,2017A030310335);Science and Technology Program of Guangzhou(201804020060);the Guangdong Natural Science Funds for Distinguished Young Scholars(2019B151502029);the Pearl River Nova Program of Guangzhou(201806010156);Outstanding Scholar Program of Guangzhou Regenerative Medicine and Health Guangdong Laboratory(2018GZR110102001);the Fundamental Research Funds for the Central Universities;L.W.thanks the Funds for Young Pearl River Scholars.
Fibronectin(Fn)is significant to the performance of biomaterials,and the chemistry of biomaterial surface play important roles in Fn adsorption and subsequent cell behavior.However,the“molecular scale”mechanism is s...