supported by Grants from the National Natural Science Foundation of China(No.81871756 and No.51672178);Innovation Fund of National Orthopaedic and Exercise Rehabilitation Clinical Medical Research Center(2021-NCRC-CXJJ-ZH-13).
Biological scaffolds have been the focus of bone tissue engineering research in recent years. In this paper, emodin (EM), macromolecular compound polycaprolactone (PCL), and hydroxyapatite (HA) were used as raw materi...
Medical implant from different materials such as metals,ceramics,polymers and composites have gained a lot of research attraction due to wide applications in medical industry for treatment,surgical operations and prep...
National Natural Science Foundation of China(Grant no.52172280);National Key R&D Program of China(Grant no.2016YFB0700803).
In the present study,it is found that the prepared alumina ceramics has better mineralization ability in a newly revised simulated body fluid.With the extension of mineralization time,the amount of hydroxyapatite(HA)c...
Glutaraldehyde(GA),the most widely used crosslinking agent for biomaterials,is cytotoxic.CaCl_(2) is of particular interest due to its non-toxic nature.Rhein can chelate Ca^(2+)and promote bone growth.Here we reported...
Surface treatments applied to titanium and its alloys for implant applications are important for the development of bio properties.In this study,first an oxide layer was formed on the surface of the titanium plate by ...
supported by the National Natural Science Foundation of China[Nos.81671826,31971257];Key Research and Development Project of the 13th Five-Year Plan[No.2016YFC1101903];China Postdoctoral Science Foundation[No.2018T110975].We would like to thank the Analytical&Testing Center of Sichuan University for using different analytic facilities.
Significant progress has been made on understanding the critical role of organic components in directing the collagen mineralization.We hypothesize that the inorganic trace elements might also play important role in t...
Nano-sized hydroxyapatite(HA)particles were synthesized by sol-gel through water and ethanol based mediums of phosphoric acid(H3PO4)and calcium hydroxide(Ca(OH)2)at pH=11 for different calcination time(1 h,2 h,4 h).Th...
Bone cements are often used for bone repair and fixation. The main objective of formulating a bone cement is to achieve structure and properties similarity to bone. In addition, bioactivity of a bone cement provides a...
Oxidized Bacterial Cellulose (OBC)-hydroxyapatite (HAp)-gelatin (Gel) nanocomposites were prepared by a biomimetic process. HAp nanocrystals were precipitated in a mixed solution ofNa2HPO4 (pH 9.2) and Gel sol...