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Long term ingestion of dietary ALEs induces metabolic disorders in mice by inducing gut dysbiosis and inhibiting AMPK/SIRT1 pathway
《Food Science and Human Wellness》2025年第2期439-449,共11页Yaya Wang Tianchang Zhang Linqing Nie Yan Zhang Junping Wang Shuo Wang 
supported by grants from the National Natural Science Foundation of China(32030083)。
Advanced lipoxidation end products(ALEs)are formed by modifying proteins with lipid oxidation products.ALEs formed in the body have been linked to diabetes and hepatic disease.However,it is not known whether ALEs form...
关键词：Dietary advanced lipoxidation end products Metabolic disorders AMPK/SITR1 signaling pathway Gut dysbiosis Intestinal barrier 
TMEM132E ablation suppresses tumor progression and restores tamoxifen sensitivity by inducing ERαexpression in triple-negative breast cancer
《Genes & Diseases》2025年第2期37-40,共4页Shang Gao Ping Sun Zekun Wang Yecheng Jin Wenjie Sun Xi Li Ruonan Duan Jiangxia Li Qiji Liu 
supported by grants from the National Key R&D Program of China (No.2022YFC2703701 to Qiji Liu);the National Natural Science Foundation of China (No.82271901,32070586);the Shandong Provincial Natural Science Foundation,China (No.ZR2020MH086);Taishan Scholar Program of Shandong Province (tsqn202211318);NHC Key Laboratory of Birth Defects Prevention,China (No.ZD202101).
Triple-negative breast cancer(TNBC)is defined by the lack of estrogen receptor(ER),progesterone receptor,and amplified human epidermal growth factor receptor expression.TNBC accounts for~15%of all breast cancer cases ...
关键词：expression. BREAST cancer 
Fibrous scaffolds loaded with BMSC-derived apoptotic vesicles promote wound healing by inducing macrophage polarization
《Genes & Diseases》2025年第2期398-413,共16页Xudong Su Jianye Yang Zhenghao Xu Li Wei Shuhao Yang Feilong Li Min Sun Yingkun Hu Wenge He Chen Zhao Li Chen Yonghua Yuan Leilei Qin Ning Hu 
supported by the National Natural Science Foundation of China (No.82072443,82372425);the Chongqing Outstanding Project of Overseas Chinese Entrepreneurship and Innovation Support Program (China) (No.CX2022032);the Articular Cartilage Tissue Engineering and Regenerative Medicine Team,Chongqing Medical University (No.W0080);the General Project of Natural Science Foundation of Chongqing,China (No.CSTB2023NSCQMSX0166);the"Tomorrow Cup"Teacher-Student Cocreation Teaching and Research Innovation Project of International Medical College of Chongqing Medical University (No.KY20220204);the Chengdu Medical Research Project (Sichuan,China) (No.2023191);the China Postdoctoral Science Foundation (No.2022M710557);the Natural Science Foundation of Chongqing,China (No.CSTB2023NSCQBHx0011);the Young Excellent Science and Technology Talent Project of the First Affiliated Hospital of Chongqing Medical University (No.ZYRC2022-05).
Macrophages play a key role in wound healing.Dysfunction of their MO polarization to M2 leads to disorders of the wound immune microenvironment and chronic inflammation,which affects wound healing.Regulating the polar...
关键词：Apoptotic body Extracellular vesicles Macrophage polarization Mesenchymal stem cells miR-21a-5p POLYCAPROLACTONE Wound healing 
Geraniol causes apoptosis in Colletotrichum gloeosporioides by inducing a burst of ROS
《Food and Health》2025年第1期2-8,共7页Bin Shao Yu-Duan Diao Qing-Li Yang Fang-Yuan Zhao Jian Ju 
the National Natural Science Foundation of China(32202192);The special fund for Taishan Scholars project(tsqn202211195).
Anthracnose is a fungal disease caused by Colletotrichum gloeosporioides, which is one of themain causes of mango rotting and deterioration, so it is important to control anthracnose.The calendula essential oil is a v...
关键词：GERANIOL Colletotrichum gloeosporioides MANGO Reactive oxygen species 
DNMT1 promotes the proliferation and migration of gastric cancer cells by inducing microRNA-125a-5p methylation to promote SERPINE1 protein
《World Journal of Gastrointestinal Oncology》2025年第3期188-201,共14页Hui Xie Hui Wang Ru-Hong Li Yue-Wen Zhang Xi-Rui Fan Xiao-Xue He Ao-Ran Guan 
the Research Program of the Science and Technology Department of Yunnan Province,No.202101AY070001-204.
BACKGROUND Gastric cancer(GC)is a malignant tumor originating from gastric mucosal epithelial cells that has high morbidity and mortality.microRNAs(miR)are important diagnostic markers and therapeutic targets in this ...
关键词：Gastric cancer microRNA-125a-5p DNA methyltransferase 1 SERPINE1 METHYLATION 
The development characteristics and formation modes of rainstorm-triggered flash flood disasters in the Hengduan Mountains
《Journal of Geographical Sciences》2025年第3期619-640,共22页LI Yifan ZHANG Chendi ZHANG Guotao 
The Second Tibetan Plateau Scientific Expedition and Research Program,No.2019QZKK0903-02;National Key R&D Program of China,No.2022YFC3002902;National Natural Science Foundation of China,No.42201086。
The Hengduan Mountains region(HMR)is one of the most densely distributed and severe flash flood disaster-prone areas in southwest China.It is also a key area for major engineering projects and beautiful countryside co...
关键词：Hengduan Mountains region rainstorm-triggered flash flood disaster-inducing condition disaster developmentcharacteristic formation mode 
NaCl inhibits Geotrichum citri-aurantii growth by inducing lipid droplets accumulation and enhances the biocontrol efficacy of Kloeckera apiculata 34-9
《Horticultural Plant Journal》2025年第1期455-458,共4页Juan Zhao Yuqing Wang Qianyi Liu Chaoan Long 
supported by the National Natural Science Foundation of China(Grant Nos.32302170&32172255);HZAU-AGIS Cooperation Fund(Grant No.SZYJY2023001)。
Decays resulting from infections by Geotrichum citri-aurantii cause a significant reduction in citrus postharvest quality and marketable yield.In the present work,0.8 mol·L^(-1)NaCl of Generally Recognized as Safe(GR...
关键词：NACL Geotrichum citri-aurantii Kloeckera apiculata LDs Postharvest preservation CITRUS 
A novel Au(III)agent designed to inhibit tumor growth and metastasis through inducing immunogenic cell death
《Rare Metals》2025年第1期430-443,共14页Wen-Juan Li Shan-He Li Xue-Yu Man Gang Xu Zhen-Lei Zhang Yao Zhang Hong Liang Feng Yang 
supported by the Natural Science Foundation of Guangxi(No.2022GXNSFGA035003);the National Natural Science Foundation of China(No.22077021).
To treat cancer and inhibit its metastasis to the greatest extent,we proposed to develop an Au(III)agent to induce immunogenic cell death(ICD)and establish long-term immunity.To this end,we optimized a series of Au(II...
关键词：Gold complex ANTICANCER THIOSEMICARBAZONE Endoplasmic reticulum stress Immunogenic cell death 
Diabetes-inducing effects of bronchial asthma
《World Journal of Diabetes》2025年第1期121-139,共19页Mohammed Al-Beltagi Adel Salah Bediwy Nermin Kamal Saeed Hosameldin A Bediwy Reem Elbeltagi 
BACKGROUND The relationship between diabetes mellitus(DM)and asthma is complex and can impact disease trajectories.AIM To explore the bidirectional influences between the two conditions on clinical outcomes and diseas...
关键词：Diabetes mellitus Bronchial asthma Glycemic control Lung function Asthma exacerbation Disease interaction MICROANGIOPATHY 
Enhancing the high-temperature stability of OFETs by inducing D-A stacking in P(NDI2OD-T2) films
《Science China Materials》2025年第1期117-124,共8页Xuetao Xiao Wenhao Li Qing Zhou Zeng Wu Xiaochan Zuo Rong Ma Yifei Xu Sichun Wang Yan Zhao 
financially supported by the Nation Key R&D Program China (2022YFB3603804);Natural Science Foundation of Shanghai (22ZR1407800);Postdoctoral Science Foundation of China (2021M700800)。
High-temperature stability of organic field-effect transistors(OFETs)is critical to ensure its long-term reliable operation under various environmental conditions.The molecular packing of donor-acceptor(D-A)conjugated...
关键词：high-temperature stability D-A stacking P(NDI2OD-T2) electrical properties OFETs 
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