云南高校图书馆联盟文献共享服务平台- INSULIN

INSULIN: 作品数：996被引量：2788H指数：21; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：张强陈薇贾伟平张大卫平其能更多>>; 相关机构：中国药科大学中国人民解放军总医院北京大学北京协和医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家教育部博士点基金更多>>

Biological correlates of psychological states among young children:a cross-sectional examination of roles of aspartate transaminase/alanine aminotransferase,insulin,and cytokines: 《Chinese Science Bulletin》2014年第35期5102-5112,共11页Kuo-Hsuan Chung Chien-Ming Hu Ying-Ru Chen Hung-Yi Chiou Yi-Hua Chen; supported by Taipei Medical University Hospital(98TMU-TMUH-01-5,99TMU-TMUH-02-4); Compared to data on adolescents and adults,limited research has been conducted on biological correlates among young children with possible psychological difficulties,especially in Asian countries.By focusing on variou...; 关键词：心理状态谷丙转氨酶细胞因子健康检查天冬氨酸转氨酶生物相胰岛素幼儿

^(99m)Tc complex conjugated to insulin: CNS radiopharmaceuticals design based on principles of blood-brain barrier transport vector: 《Chinese Science Bulletin》2005年第20期2297-2301,共5页LIU Fei FAN Caiyun ZHANG Jinming WANG Wushang LIU Boli; This work was supported by the Na—tional Natural Science Foundation ofChina(Grant No.20471011).; Hydrophilic 99mTc-EC and nonlipophilic 99mTc- MAMA′-BA complexes, owing to the existing of intact blood-brain barrier (BBB) in vivo, cannot cross from blood to brain. Previous studies showed that insulin is selective...; 关键词：血脑屏障 BBB 生理功能胰岛素接受体脑传输

Insulin improves cardiac myocytes contractile function recovery in simulated ischemia-reperfusion:Key role of Akt被引量：9: 《Chinese Science Bulletin》2003年第13期1364-1369,共6页ZHANG Bo, ZHANG Haifeng, FAN Qian, MA Xinliang & GAO Feng Department of Physiology, The Fourth Military Medical University,Xi抋n 710032, China Correspondence should be addressed to Gao Feng (e-mail: fgao@fmmu.edu.cn); supported by the National Natural Science Foundation of China (Grant Nos.39970302 and 39970807);the National Science Fund for Distinguished Young Scholars(Grant No.39925013).; The present study examined cardiac myocytecontractile and Ca2+ transient responses to insulin duringsimulated ischemia/reperfusion (I/R) and furtherinvestigated the role of protein kinase B (Akt) in the insulin-induce...; 关键词：胰岛素心脏肌细胞收缩功能局部缺血钙离子

Salt and pH-dependent properties of native and mutant insulin: 《Chinese Science Bulletin》2002年第6期464-466,共3页MA Xiaohui LI Chunhua LU Benzhuo CHEN Weizu WANG Cunxin XU Xiaojie; This work was supported in part by the National Natural Science Foundation of China (Grant No. 29992590-2);the Beijing Natural Science Foundation (Grant No. 5992002);the Development Project of Scientific Technology of the Education Commission of Beiji; A fast and effective model for predicting the salt and pH dependent properties of protein complexes is presented. It is based on the formal charge parameter sets of ionizable groups and applied in conjunction with the...; 关键词：FORMAL charge electrostatic interaction INSULIN Pois-son-Boltzmann equation.

Lanthanides' enhancing absorption of insulin and reduction of blood glucose of rat by pulmonary administration被引量：1: 《Chinese Science Bulletin》2000年第7期604-608,共5页Yi Cheng Zancong Shen Qiang Zhang Rongchang Li Shuli Wei Kui Wang; To explore the possibility of lanthanides as the enhancer of insulin absorption, the promoting effects of lanthanide ions on the absorption of intrapulmonary delivered insulin and reduction of blood glucose were inves...; 关键词：LANTHANIDE INSULIN BLOOD GLUCOSE rat.

Preliminary crystallographic studies on two insulin analogues which retain high biological activities after alterations in A chain: 《Chinese Science Bulletin》1999年第16期1480-1483,共4页Yiding Huang Hui Chen Youmin Feng Jiping Zhang; Using Fmoc solid phase synthesis and site-directed gene mutagenesis, two insulin analogues, [A13-14GABA,A21Ala] porcine insulin and [A3Thr] human insulin, have been prepared respectively, which retain high biological ...; 关键词：[A13-14GABA.A21Ala] PORCINE INSULIN [A3Thr] human INSULIN INSULIN ANALOGUE crystal culture X-ray diffraction.

Crystallization and preliminary crystallographic analyses of human insulin mutant B9(Ser→Asp)in different aggregation forms: 《Chinese Science Bulletin》1999年第9期796-799,共4页Xinqi Liu Lei Jin Ying Zhang Markussen Jan Dacheng Wang; B9(Ser→Asp) insulin, one of the fast-acting insulin mutants produced by protein engineering, has been crystallized. Three crystal forms have been obtained, which belong to orthorhombic, tetragonal and rhombohedral sy...; 关键词：INSULIN mutant. B9Asp INSULIN CRYSTALLIZATION crystallographic parameter.

Crystallization and preliminary crystallographic studies of insulin T_3R_3 states created in different conditions: 《Chinese Science Bulletin》1998年第1期59-62,共4页AI Xi ZENG Zonghao HUANG Peitang Jan Markussen WANG Dacheng; theNationalHigh_TechProgramofChina; In the presence of a series of small organic molecules including 1, 4 dioxane, DMF, isopropanol, rDNA human insulin, mutants A21 Asn→Ser and (A21 Asn→Ser, B27 Thr→Arg) human insulin have been crystallized in both Z...; 关键词：INSULIN T_3R_3 structure EFFECTOR CRYSTALLIZATION preliminary crystallographic study cell constants.

Preliminary crystallographic studies on Des-(Phe-Val-Asn)^(B1-3)-insulin: 《Chinese Science Bulletin》1997年第6期507-510,共4页JIN Rongsheng, WAN Zhuli and LIANG DongcaiState Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, Chin; THE results of the X-ray analysis of the three-dimensional structure of insulin have shown that, in rhombohedral 2-Zn insulin, the N-terminal segment of the B-chain is on the surface of the monomer and dimmer of insul...; 关键词：Des-(Phe-Val-Asn)^B1-3 -insulin crystal growth X-ray diffraction.

Crystallization and preliminary crystallographic analysis of [A21Ser-B27Arg-B30Thr-NH_2]-human insulin: 《Chinese Science Bulletin》1995年第11期949-952,共4页金雷张林王大成 Jan Markussen; Project supported by UNIDO grant (91/048) and "863" High-Tech Program of China (863-21-01).; Some experiments have shown that the properties of single mutation can be synthesizedin a mutant with multiple mutations. Following this idea, SRN-HI was prepared.Markussen et al.reported that a high stability and a p...; 关键词：INSULIN multiple MUTATIONS high stability PROLONGED action crystallographic data.

INSULIN