ISCHEMIA-REPERFUSION

作品数:210被引量:1347H指数:17
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相关领域:医药卫生更多>>
相关作者:张均田陈永红杜冠华张玲妹孙凤艳更多>>
相关机构:中国医学科学院北京协和医学院上海医科大学中国药科大学中国科学院上海生命科学研究院更多>>
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相关基金:国家自然科学基金中国博士后科学基金湖北省自然科学基金国家教育部博士点基金更多>>
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Contribution of Myocyte Apoptosis to Myocardial Injury in an in Vivo Rabbit Preparation of Ischemia-Reperfusion
《World Journal of Cardiovascular Diseases》2022年第8期426-438,共13页John G. Kingma 
Objective: Exposure of the heart to repeated, brief episodes of coronary occlusion/reperfusion prevents lethal myocyte injury. Necrosis and apoptosis, two seemingly distinct mechanisms of cell death caused by ischemia...
关键词:Ischemia REPERFUSION Ischemic Conditioning Necrosis APOPTOSIS DNA Fragmentation PARP Cleavage Rabbits 
NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury被引量:5
《Acta Pharmacologica Sinica》2022年第8期2081-2093,共13页Zhi-yong Xie Wei Dong Li Zhang Meng-jie Wang Zhen-meng Xiao Yu-hua Zhang Wan-xin Shi Ying Huang Yan Yang Cui-li Li Lei Fu Xing-chen Zhao Rui-zhao Li Zhi-lian Li Yuan-han Chen Zhi-ming Ye Shuang-xin Liu Zheng Dong Xin-ling Liang 
supported by National Natural Science Foundation of China(Grant No.81770667);Scientific Research Project of Guangdong Provincial People’s Hospital-Summit plan(Grant No.KJ012019120,No.KJ012019433);Guangdong-Hong Kong Joint Laboratory on Immunological and Genetic Kidney Diseases(Grant No.2019B121205005).
Acute kidney injury(AKI)with maladaptive tubular repair leads to renal fibrosis and progresses to chronic kidney disease(CKD).At present,there is no curative drug to interrupt AKI-to-CKD progression.The nuclear factor...
关键词:acute kidney injury chronic kidney disease NFAT2 11R-VIVIT renal fibrosis APOPTOSIS renal tubular epithelial cells HK-2 cells 
Correlation between myocardial ischemia-reperfusion-induced monophasic action potential amplitude change and myocardial damage
《Journal of Hainan Medical University》2017年第17期9-12,共4页Ying-Ying Liu Qin Li 
Objective:To study the correlation between myocardial ischemia-reperfusion-induced monophasic action potential amplitude (MAPA) change and myocardial damage.Methods:New Zealand rabbits were selected as experimental an...
关键词:MYOCARDIAL ISCHEMIA-REPERFUSION MONOPHASIC action potential OXIDATIVE stress APOPTOSIS 
Comparison of pre-treatment and post-treatment use of selenium in retinal ischemia reperfusion injury被引量:3
《International Journal of Ophthalmology(English edition)》2015年第2期263-268,共6页Alper Yazici Hasan Aksit Esin Sogutlu Sari Arzu Yay Haydar Ali Erken Dilek Aksit Harun Cakmak Kamil Seyrek Sitki Samet Ermis 
AIM: To investigate the effects of selenium in rat retinal ischemia reperfusion(IR) model and compare pretreatment and post-treatment use.METHODS: Selenium pre-treatment group(n =8) was treated with intraperitoneal(i....
关键词:RETINA SELENIUM ISCHEMIA-REPERFUSION APOPTOSIS pre-treatment POST-TREATMENT oxidative stress 
Role of sirtuins in ischemia-reperfusion injury被引量:8
《World Journal of Gastroenterology》2013年第43期7594-7602,共9页Eirini Pantazi Mohamed Amine Zaouali Mohamed Bejaoui Emma Folch-Puy Hassen Ben Abdennebi Joan Roselló-Catafau 
Supported by AGAUR,No.2012FI_B00382,Generalitat de Catalunya,Barcelona,Spain,to Pantazi E;CSIC for the development program to Bejaoui M,No.I-COOP0005;The Fondo de Investigaciones Sanitarias,No.FIS PI12/00519
Ischemia-reperfusion injury(IRI)remains an unresolved and complicated situation in clinical practice,especially in the case of organ transplantation.Several factors contribute to its complexity;the depletion of energy...
关键词:SIRTUIN 1 SIRTUIN 3 ISCHEMIA-REPERFUSION INJURY OXIDATIVE stress APOPTOSIS 
Effects of Chinese Herbal Medicine Serum on the Apoptosis of Sinoatrial Node Cells Induced by Simulated Ischemia-reperfusion被引量:5
《Journal of Traditional Chinese Medicine》2011年第3期224-227,共4页刘如秀 谭双 李敏 彭杰 汪艳丽 刘志明 
supported by the fund from the State Administration of Traditional Chinese Medicine (No.04-05JP61)
Objective:To study the effect of Chinese herbal medicine Kangxin Fumai Granule(康心复脉颗粒 Granule for heart diseases) serum on the primary cultured sinoatrial node(SAN) cell apoptosis induced by simulated ischemia-r...
关键词:Chinese herbal medicine serum pharmacology ISCHEMIA-REPERFUSION sinoatrial node cell apoptosis 
Sevoflurane preconditioning and postconditioning attenuate apoptosis induced by ischemia-reperfusion in rat lung
《中国现代医学杂志》2011年第6期718-726,共9页Qing Li Su-pin Zhang Timo Rinne Yong-hao Yu Guo-lin Wang 
Objective To investigate the effect of sevoflurane preconditioning and postconditioning on lung ischemia-reperfusion(IR) injury and apoptosis in rat.Methods Wistar rats were randomly assigned to four groups:sham group...
关键词:ischemia-reperfusion induced injury APOPTOSIS SEVOFLURANE PRECONDITIONING POSTCONDITIONING 
GdCl<sub>3</sub> abates hepatic ischemia-reperfusion injury by inhibiting apoptosis in rats被引量:1
《Hepatobiliary & Pancreatic Diseases International》2009年第5期518-523,共6页
supported by a grant from the Science Foundation of Liaoning Province,China(No.20042064)
BACKGROUND:Gadolinium chloride(GdCl3)is a specific inhibitor of Kupffer cells(KCs),which are important promoters of various liver injuries.It is therefore of interest to explore the role of KCs in liver ischemia-reper...
关键词:GADOLINIUM chloride KUPFFER cell ISCHEMIA-REPERFUSION injury caspase-3 APOPTOSIS 
Effects of Ethyl Pyruvate on Myocardial Apoptosis and Expression of Bcl-2 and Bax Proteins after Ischemia-reperfusion in Rats被引量:26
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2008年第3期281-283,共3页郭家龙 张凯伦 季艳梅 蒋雄刚 左顺庆 
In order to study the effects of ethyl pyruvate on cardiomyocyte apoptosis following ischemia/reperfusion (I/R) in vitro and the expression of Bcl-2 and Bax proteins, isolated rat hearts were perfused in a Langendor...
关键词:ethyl pyruvate myocardial reperfusion injury APOPTOSIS Bcl-2 protein Bax protein 
Role of mitogen-activated protein kinases in the regulation of paraventricular nucleus to gastric ischemia-reperfusion injuries被引量:17
《Chinese Medical Journal》2007年第12期1082-1087,共6页LI Li ZHANG Yong-mei QIAO Wei-li ZHANG Jian-fu WANG Lin 
grants from the National Natural Science Foundation of China(No.30370533and30570671);Educational Department Science Research Foundation of Jiangsu Province(No. 05KJB310134)
Background We investigated the role in electrical stimulations of paraventricular nucleus (PVN) on gastric mucosal cells and the activity of mitogen-activated protein kinases (MAPKs) family members induced by gast...
关键词:paraventricular nucleus gastric ischemia-reperfusion PROLIFERATION apoptosis mitogen-activated protein kinases 
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