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作品数:266被引量:370H指数:10
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相关领域:医药卫生更多>>
相关作者:汤霞靖蒋劲姚克申屠形超金冲飞更多>>
相关机构:中国科学院浙江大学医学院附属第二医院华南农业大学北京大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金中国博士后科学基金更多>>
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Intersection of mitochondrial dysfunction and myelination:An overlooked aspect in neurodevelopmental disorders
《Neural Regeneration Research》2026年第2期659-660,共2页Ariel Nir Sade Gal Wiener Boaz Barak 
Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables th...
关键词:neurodevelopmental disorders ndds rokach white matter developing brain MYELINATION neurodevelopmental processes mitochondrial dysfunction white matter wm known developing braina 
Newly identified intronic and known pathogenic point mutations in SLC34A3/NPT2c cause hereditary hypophosphatemic rickets with hypercalciuria
《Genes & Diseases》2025年第2期68-71,共4页Yujing Sun Yuan Liu Xiaoli Zhang Ling Jiang 
funded by the National Natural Science Foundation of China Youth Fund (No.82200918);the Natural Science Foundation of Shandong Province Youth Fund (China) (No.ZR2021QC111).
Hereditary hypophosphatemic rickets with hypercalciuria(HHRH)is a rare autosomal recessive disorder characterized by hypophosphatemia,hypercalciuria,and recurrent nephrolithiasis,often resulting in rickets and osteoma...
关键词:calci SLC HEREDITARY 
An Efficient Hyperbolic Kernel Function Yielding the Best Known Iteration Bounds for Linear Programming
《Acta Mathematicae Applicatae Sinica》2025年第1期133-151,共19页Imene TOUIL Wided CHIKOUCHE Djamel BENTERKI Amina ZERARI 
Interior-point methods(IPMs) for linear programming(LP) are generally based on the logarithmic barrier function. Peng et al.(J. Comput. Technol. 6: 61–80, 2001) were the first to propose non-logarithmic kernel functi...
关键词:linear programming primal-dual interior-point methods kernel functions complexity analysis large and small-update methods 
kProtoClust:Towards Adaptive k-Prototype Clustering without Known k
《Computers, Materials & Continua》2025年第3期4949-4976,共28页Yuan Ping Huina Li Chun Guo Bin Hao 
supported by the National Natural Science Foundation of China under Grant No.62162009;the Key Technologies R&D Program of He’nan Province under Grant No.242102211065;the Scientific Research Innovation Team of Xuchang University under GrantNo.2022CXTD003;Postgraduate Education Reform and Quality Improvement Project of Henan Province under Grant No.YJS2024JD38.
Towards optimal k-prototype discovery,k-means-like algorithms give us inspirations of central samples collection,yet the unstable seed samples selection,the hypothesis of a circle-like pattern,and the unknown K are st...
关键词:Prototype finding convex hull support vector data description geometrical information 
Known and unknown:Exosome secretion in tumor microenvironment needs more exploration
《Genes & Diseases》2025年第1期158-171,共14页Mengxiang Huang Jie Ji Xuebing Xu Dandan Jin Tong Wu Renjie Lin Yuxuan Huang Jiawen Qian Zhonghua Tan Feng Jiang Xiaogang Hu Weisong Xu Mingbing Xiao 
supported by grants from the National Natural Science Foundation of China(No.82272624);the Natural Science Foundation of Jiangsu Province,China(No.BK20211105);the Plan of Jiangsu Provincial Medical Key Discipline(China)(No.ZDXK202240);the Social Development Foundation of Nantong City,Jiangsu,China(No.MS22022044,JC22022001,JCZ2022027);the Health Project of Nantong City,Jiangsu,China(No.MS2022056);the Postgraduate Research and Practice Innovation Program of Jiangsu Province,China(No.SJCX21_1452,KYCX21_3112,KYCX23_3419);Jiangsu Provincial Research Hospital(China)(YJXYY202204);the Jiangsu Administration of Traditional Chinese Medicine(China)(JD2022SZ07);Teaching Research Project of Affiliated Hospital of Nantong University(China)(Tfj22002).
Exosomes,extracellular vesicles originating from endosomes,were discovered in the late 1980s and their function in intercellular communication has since garnered considerable interest.Exosomes are lipid bilayer-coated...
关键词:Exosome cargo Exosome secretion Intercellular communication TUMOR Tumor microenvironment 
Why Is This Tibetan Buddhist Monastery Known as "DUNHUANG IN THE SNOWY LAND"?
《China's Tibet》2025年第1期36-41,共6页Zhao Yan Huang Wenjuan(Translated) 
Located in Sakya County,an ancient city nestled at the foot of the Himalayas,the 950-year-old Sakya Monastery majestically spans both the southern and northern banks of the Zhongqu River.Renowned for its distinctive a...
关键词:TIBETAN ARCHITECTURAL journal 
Known yet underdiagnosed:Invasive assessment of coronary microvascular disease and its implications
《World Journal of Cardiology》2025年第1期8-14,共7页Sukhdeep Bhogal Akash Batta Bishav Mohan 
Coronary microvascular disease(CMD)is one of the commonest causes of cardiac chest pain.The condition is more prevalent in women,and incidence is known to increase with age,hypertension,and diabetes.The pathophysiolog...
关键词:Coronary microvascular disease Endothelial dysfunction Invasive assessment Coronary flow reserve Hyperemic myocardial velocity resistance Pressurewire X 
Ligamentoplasty of the Ankle Periosteum Known as Roy-Camille/Saillant at the Orthopedic Traumatology Department of the Pau Hospital Center (France)
《Open Journal of Orthopedics》2024年第12期571-578,共8页Diallo Mamadou Moustapha Eric Hammel Bah Mohamed Lamine Lamah Léopold 
Introduction: Chronic ankle instability comprises two main entities, often associated with mechanical instability due to ligament and/or bone trauma, and functional instability due to a postural or proprioceptive defe...
关键词:Instability ANKLE Ligamentoplasty PERIOSTEUM 
Multiomics profiling reveals VDR as a central regulator of mesenchymal stem cell senescence with a known association with osteoporosis after high-fat diet exposure
《International Journal of Oral Science》2024年第4期695-710,共16页Jiayao Chen Shuhong Kuang Jietao Cen Yong Zhang Zongshan Shen Wei Qin Qiting Huang Zifeng Wang Xianling Gao Fang Huang Zhengmei Lin 
supported by grants from the National Natural Science Foundation of China(grants No.81873713 and No.U22A20157)。
The consumption of a high-fat diet(HFD)has been linked to osteoporosis and an increased risk of fragility fractures.However,the specific mechanisms of HFD-induced osteoporosis are not fully understood.Our study shows ...
关键词:OSTEOPOROSIS VITAMIN thereby 
Lyuliang — Land Known for Its Revolutionary Genes
《China News Release》2024年第6期78-82,共5页Lyu Xuanwen 
Lyuliang City Lyuliang is a prefecture-level city under the jurisdiction of north China's Shanxi Province.It is adjacent to Taiyuan City,the capital of Shanxi Province,and Jinzhong City to the east,faces Shaanxi Provi...
关键词:Taiyuan SHANXI TEMPERATE 
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