LTP

作品数：398被引量：1158H指数：14
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AVP(4-8) Improves Cognitive Behaviors and Hippocampal Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease被引量：3
《Neuroscience Bulletin》2020年第3期254-262,共9页Xiumin Zhang Fang Zhao Chenfang Wang Jun Zhang Yu Bai Fang Zhou Zhaojun Wang Meina Wu Wei Yang Junhong Guo Jinshun Qi 
the National Natural Science Foundation of China(31471080);the Scientific Program for“Sanjin Scholars”of Shanxi Province,Shanxi“1331 Project”Key Subjects Construction(1331KSC);Science Foundation for Excellent Young Scholars of Shanxi Province,China(201801D211005)。
Memory deficits with aging are related to the neurodegeneration in the brain, including a reduction in arginine vasopressin(AVP) in the brain of patients with Alzheimer’s disease(AD). AVP(4-8), different from its pre...
关键词：AVP(4-8) APP/PS1 TRANSGENIC mice Cognitive behavior SYNAPTIC plasticity In vivo HIPPOCAMPAL LTP 
Effects of four components from Uncaria rhynchophylla on LTP impairment induced by lipopolysaccharide
《中国药理学与毒理学杂志》2019年第9期737-737,共1页SUN Na WANG Chen HUANG Yan ZHOU Wen-xia ZHAO Qin-shi 
Open Fund from the State Key Laboratory of Phytochemistry and Plant Resources in West China(P2017-KF13);National Science and Technology Major Project of China(2016ZX09J16104)
OBJECTIVE To evaluate the neuroprotective effects of 4 components from Uncaria rhynchophylla(297,307,315 and 327)on long-term potentiation(LTP)deficit in neuroinflammation animal model induced by lipopolysaccha⁃ride(L...
关键词：LIPOPOLYSACCHARIDE HIPPOCAMPAL long-term potentiation 
Comparative Study of ROCK1 and ROCK2 in Hippocampal Spine Formation and Synaptic Function被引量：9
《Neuroscience Bulletin》2019年第4期649-660,共12页Jinglan Yan Youcan Pan Xiaoyan Zheng Chuanan Zhu Yu Zhang Guoqi Shi Lin Yao Yongjun Chen Nenggui Xu 
the National Science Foundation of China (81774406 and 31571041);the Guangdong Innovative and Entrepreneurial Research Team Program (Natural Science) (2017KCXTD006);Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme (2016);the Scientific Research and Innovation Team Program of Guangzhou University of Chinese Medicine (2017KYTD03)
Rho-associated kinases(ROCKs)are serinethreonine protein kinases that act downstream of small Rho GTPases to regulate the dynamics of the actin cytoskeleton.Two ROCK isoforms(ROCK1 and ROCK2)are expressed in the mamma...
关键词：Rho-associated kinases SPINE HIPPOCAMPUS STP LTP Spatial learning and memory 
The role of the N-methyl-D-aspartate receptor in the proliferation of adult hippocampal neural stem and precursor cells被引量：6
《Science China(Life Sciences)》2014年第4期403-411,共9页TAYLOR Chanel J HE RongQiao BARTLETT Perry F 
New neurons are continuously generated from resident pools of neural stem and precursor cells(NSPCs)in the adult brain.There are multiple pathways through which adult neurogenesis is regulated,and here we review the r...
关键词：adult neurogenesis stem cell precursor cell NMDA receptor HIPPOCAMPUS synaptic plasticity long-term potentiation（LTP） 
Effects of the ephedra alkaloid methylephedrine on the basal evoked potential transportation and the long-term potentiation (LTP) in the rat hippocampal dentate granule cells in vivo
《沈阳药科大学学报》2008年第S1期62-62,共1页PENG Xiao-dong(Department of Pharmacology,Ningxia Medical University,Yinchuan 750004,China) 
Objective The effect of the ephedra/ephedrine alkaloid methylephedrine(dl-methylephedrine hydrochloride for testing in this paper)on cognitive related synaptic plasticity was investigated by recording extracellular fi...
关键词：EPHEDRA methylephedrine EVOKED potential LTP HIPPOCAMPAL GRANULE cells in vivo 
Effects of Chronic Stress and Phenytoin on the Long-term Potentiation (LTP) in Rat Hippocampal CA1 Region被引量：1
《Acta Biochimica et Biophysica Sinica》2004年第5期375-378,共4页HuiZHENG QuanYANG Chong-TaoXU 
To investigate the changes of LTP in hippocampal CA1 region induced by chronic stress and the effect of phenytoin on them, thirty-two adult male Sprague-Dawley rats were randomly divided equally into four groups...
关键词：PHENYTOIN long-term potentiation HIPPOCAMPUS stress 
The Role of Monosialoganglioside GM1 in LTP-Induction in Rat Hippocampal Slices
《Science China Chemistry》1994年第5期581-589,共9页李永新 梅镇彤 
Project supported by Shanghai Sciences and Technology Committee.
The effect of monosialoganglioside GM1 of different doses on the long-term potentiation (LTP) of synaptic transmission has been studied in the CA1 region of rat hippocampal slices, and the possible role that calcium i...
关键词：MONOSIALOGANGLIOSIDE GM1 HIPPOCAMPAL SLICE long-term POTENTIATION (LTP) rats. 
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