supported by a grant from the Health Research New Zealand(HRC)22/559(to AJG and LB)。
Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental disability.Detailed asse...
supported by the National Natural Science Foundation of China,Nos.82371886(to JY),81925020(to DM),82202797(to LW),and 82271218(to CZ).
Alzheimer’s disease is a common neurodegenerative disorder defined by decreased reasoning abilities,memory loss,and cognitive deterioration.The presence of the blood-brain barrier presents a major obstacle to the dev...
supported by the National Key R&D Program of China,No.2021YFF0702203(to HYL);the National Natural Science Foundation of China,No.82101323(to TS);Preferred Foundation of Zhejiang Postdoctors,No.ZJ2021152(to TS).
Parkinson’s disease is a common neurodegenerative disorder that is associated with abnormal aggregation and accumulation of neurotoxic proteins,includingα-synuclein,amyloid-β,and tau,in addition to the impaired eli...
supported by China Scholarship Council(202208210093,to RJ)。
Cerebral small vessel disease is a neurological disease that affects the brain microvasculature and which is commonly observed among the elderly.Although at first it was considered innocuous,small vessel disease is no...
Amblyopia is the most common cause of vision loss in children and can persist into adulthood in the absence of effective intervention.Previous clinical and neuroimaging studies have suggested that the neural mechanism...
supported by the National Natural Science Foundation of China,No.81771892(to JHC).
The neuronal differentiation of mesenchymal stem cells offers a new strategy for the treatment of neurological disorders.Thus,there is a need to identify a noninvasive and sensitive in vivo imaging approach for real-t...
supported by the National Natural Science Foundation of China, Nos.82001767(to XJG), 81971577(to MMZ), 82171888(to XJX);the Natural Science Foundation of Zhejiang Province of China, Nos.LQ21H180008(to XJG), LQ20H180012(to MX);the China Postdoctoral Science Foundation, Nos.2021T140599(to XJG), 2019M662082(to XJG);the 13th Five-year Plan for National Key Research and Development Program of China, No.2016YFC1306600(to MMZ)
Brain radiomics can reflect the characteristics of brain pathophysiology.However,the value of T1-weighted images,quantitative susceptibility mapping,and R2*mapping in the diagnosis of Parkinson’s disease(PD)was under...
supported by Beijing Municipal Health Commission of China,No.Jing2019-2(to TLW)。
Hypothermia is an important protective strategy against global cerebral ischemia following cardiac arrest.However,the mechanisms of hypothermia underlying the changes in different regions and connections of the brain ...
Structural brain changes indicative of dementia occur up to 20 years before the onset of clinical symptoms. Efforts to modify the disease process after the onset of cognitive symptoms have been unsuccessful in recent ...
Cognitive impairments are commonly observed in patients with multiple sclerosis and are associated with lower levels of quality of life.No consensus has been reached on how to tackle effectively cognitive decline in t...