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相关作者：方亚李洪福郭军吴辉文蔡伟明更多>>
相关机构：厦门大学南京医科大学华中农业大学第二军医大学更多>>
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Increased excitatory amino acid transporter 2 levels in basolateral amygdala astrocytes mediate chronic stress–induced anxiety-like behavior
《Neural Regeneration Research》2025年第6期1721-1734,共14页Xirong Xu Shoumin Xuan Shuai Chen Dan Liu Qian Xiao Jie Tu 
supported by the National Natural Science Foundation of China,Nos.32371070 (to JT),31761163005 (to JT),32100824 (to QX);the Shenzhen Science and Technology Program,Nos.RCBS20210609104606024 (to QX),JCY20210324101813035 (to DL);the Guangdong Provincial Key S&T Program,No.2018B030336001 (to JT);the Key Basic Research Program of Shenzhen Science and Technology Innovation Commission,Nos.JCYJ20200109115405930 (to JT),JCYJ20220818101615033 (to DL),JCYJ20210324115811031 (to QX),JCYJ20200109150717745 (to QX);Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases,No.ZDSYS20220304163558001 (to JT);Guangdong Provincial Key Laboratory of Brain Connectome and Behavior,No.2023B1212060055 (to JT);the China Postdoctoral Science Foundation,No.2021M693298 (to QX)。
The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain functio...
关键词：ANXIETY ASTROCYTES basolateral amygdala behavior dihydrokainic acid excitatory amino acid transporter 2 fiber photometry GLUTAMATE LDN-212320 TRANSPORTER 
Endoplasmic reticulum stress and forkhead box protein O1 inhibition mediate palmitic acid and high glucose-inducedβ-cell dedifferentiation
《World Journal of Diabetes》2025年第5期216-233,共18页Li-Kun Wang Chu-Chu Kong Ting-Yan Yu Hui-Song Sun Lu Yang Ying Sun Ming-Yu Li Wei Wang 
Supported by the Natural Science Foundation of China,No.81471081;the Natural Science Foundation of Fujian Province,No.2023D009;the Natural Science Foundation of Xiamen City,No.3502Z202373104 and No.3502Z20227162;Scientific Research Foundation for Advanced Talents,Xiang’an Hospital of Xiamen University,No.PM201809170005。
BACKGROUND Type 2 diabetes mellitus is characterized by pancreaticβ-cell dysfunction and insulin resistance.Studies have suggested thatβ-cell dedifferentiation is one of the pathogeneses ofβ-cell dysfunction,but th...
关键词：β-cell dedifferentiation High glucose and palmitic acid Forkhead box O1 RNA-sequencing Endoplasmic reticulum stress 
Reactive oxygen species mediate ovarian cancer development,platinum resistance,and angiogenesis via CXCL8 and GSK-3β/p70S6K1 axis
《Genes & Diseases》2025年第2期133-135,共3页Jiange Qiu Qing Xu Tahira Panah A K M Helal Morshed Xue Wang Fengmei Zhou Wenjing Liu Jufeng Wang Ye Zhang Bingjie Liu Bing-Hua Jiang 
supported by the National Natural Science Foundation of China (No.81903174,82073393);the Provincial Health Commission of Henan,China (No.SBGJ202003013,LHGJ20190656);the Medical Science and Technology Research Plan Provincial Co-construction Project of Henan Province,China (No.SBGJ202302023);the Medical Science and Technology Project of Henan Province,China (No.SB201901110).
Ovarian cancer is one of the leading causes of cancerrelated deaths in women worldwide,with a five-year overall survival rate of less than 50%or30%if it is in the advanced stages.1 Reactive oxygen species(ROS)are typi...
关键词：ANGIOGENESIS cancer PLATINUM 
Peritoneal adipose stem cell-derived extracellular vesicles mediate the regulation of ovarian cancer cell proliferation and migration through EGFR-NF-κB signaling
《Genes & Diseases》2025年第2期350-367,共18页Lian Wang Ning Luo Jihui Zhu Zubaidan Sulaiman Wenhan Yang Ke Hu Guihai Ai Weihong Yang Xiaowen Shao Shengkai Jin Xue Zhang Yantao Fan Dan Deng Zhongping Cheng Zhengliang Gao 
supported by funds from the National Key R&D Program of China (No.2019YFA0110300 to ZLG);the National Natural Science Foundation of China (No.31900522 to LW,81773302 to YTF,32370895,82373269 to ZPC,32070862 to ZLG);supported by the Fundamental Research Funds for the Central Universities of China (project plan 22120210588);the Climbing Talent Program of Shanghai Tenth People's Hospital (China) (No.2021SYPDRC036);the China Postdoctoral Science Foundation (No.2019M651571).
Peritoneal dissemination frequently develops in patients with ovarian cancer(OC)and is associated with recurrence and metastasis.However,the cellular components and mechanisms supporting Oc peritoneal metastasis are p...
关键词：Adipose-derived stem cells EGFR/NK-κB axis Extracellularvesicles METASTASIS Ovarian cancer 
How surface electronegativity and calcium release in enamel mediate the adsorption and lubrication of salivary proteins:The role of interfacial water
《Friction》2025年第3期67-78,共12页Yue Tang Lei Lei Hujun Wang Haonan Qiu Jing Zheng Zhongrong Zhou 
supported by the National Natural Science Foundation of China(Nos.52305217,52075459,and 51675449).
This study investigated the effect of surface electronegativity and calcium release from human enamel on the adsorption and lubrication of salivary proteins from the perspective of interfacial water using three model ...
关键词：salivary proteins ADSORPTION LUBRICATION ELECTRONEGATIVITY calcium release interfacial water 
Endophytic Fungi Mediate Plant Growth and Promote the Accumulation of Secondary Metabolites
《Plant Diseases and Pests》2025年第1期24-30,33,共8页Shuping WU Shunxing YANG Shiqiong LUO Wenxuan QUAN Zhannan YANG Tianhua YU 
Supported by the Key Field Project of Guizhou Provincial Education Department(KY[2021]044);Guizhou Forestry Science Research Project(QJH KY[2021]11);Guizhou Higher Education Characteristic Key Laboratory Construction Project(QJH KY[2021]002).
[Objectives]To investigate the mechanism of endophytic fungi mediating the plant growth and promoting the accumulation of secondary metabolites in Camellia oleifera.[Methods]Four strains of endophytic fungi isolated f...
关键词：Camellia oleifera Endophytic fungi Secondary metabolite 
Vacuolar phosphate efflux transporter ZmVPEs mediate phosphate homeostasis and remobilization in maize leaves
《Journal of Integrative Plant Biology》2025年第2期311-326,共16页Zhenhui Guo Chaonan Zhang Hongyu Zhao Yu Liu Xiyao Chen Hanshu Zhao Limei Chen Wenyuan Ruan Yifang Chen Lixing Yuan Keke Yi Lei Xu Jingbo Zhang 
supported by grants from the National Key Research and Development Program of China(2021YFF1000501 and 2022YFD1900704);National Natural Science Foundation of China(32070306,32172667,and U23A20178);the Chinese Universities Scientific Fund(2023RC015);the 2115 Talent Development Program of China Agricultural University;the Central PublicInterest Scientific Institution Basal Research Fund(Y2022QC14)。
Phosphorus(P)is an essential macronutrient for plant growth and development.Vacuoles play a crucial role in inorganic phosphate(Pi)storage and remobilization in plants.However,the physiological function of vacuolar ph...
关键词：LEAVES maize phosphate remobilization vacuolar phosphate efflux ZmVPEs 
Tannic acid-based metal-phenolic networks as a versatile platform to mediate cell therapy被引量：1
《Science China Materials》2024年第12期3833-3848,共16页Huilong Luo Juan Xie Xuechun Su Panpan Wang Huan Chen Xiao Kuang Jinyao Liu 
financially supported by the National Natural Science Foundation of China(22425505,82204503,22305152,and 22407089);the Explorer Program of the Science and Technology Commission of Shanghai Municipality(21TS1400400);the Two-hundred Talent(20181704)。
Surface modification using biomaterials is crucial for constructing bioactive interfaces that can control cell behavior,regulate biological processes,and interact with specific biomolecules.Tannic acid(TA),a naturally...
关键词：tannic acid POLYPHENOLS metal-phenolic networks interface engineering cell therapy 
GABAergic Retinal Ganglion Cells Projecting to the Superior Colliculus Mediate the Looming-Evoked Flight Response
《Neuroscience Bulletin》2024年第12期1886-1900,共15页Man Yuan Gao Tan Danrui Cai Xue Luo Kejiong Shen Qinqin Deng Xinlan Lei Wen-Bo Zeng Min-Hua Luo Lu Huang Chaoran Ren Yin Shen 
supported by grants from the National Key R&D Program of China(2017YFE0103400);the National Natural Science Foundation of China(81470628 and 82471086).
The looming stimulus-evoked flight response to approaching predators is a defensive behavior in most animals. However, how looming stimuli are detected in the retina and transmitted to the brain remains unclear. Here,...
关键词：scpgRGCs Innate defensive behavior GABA LOOMING Superior colliculus Flight response 
Precipitation-induced soil properties and plant communities mediate root strategies in an alpine meadow
《Journal of Plant Ecology》2024年第6期132-145,共14页Yi-Heng Li Xin-Di Zhang Min Liu Chang-Ting Wang Lerdau Manuel Lei Hu 
supported by the National Key R&D Program of China(2023YFF1304304);the National Natural Science Foundation of China(U20A2008);the Project of Grassland Multifunctionality Evaluation in Three-River-Source National Park(QHQXD–2023–28);the Fundamental Research Funds for the Central Universities,Southwest Minzu University(ZYN2023072).
Plant roots show flexible traits to changing precipitation,but the factors driving root trait covariation remain poorly understood.This study investigated six key root traits and explored the potential driving factors...
关键词：fine roots root economic space root foraging strategy plant communities precipitation gradients 
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