MESALAZINE

作品数:36被引量:111H指数:6
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相关领域:医药卫生更多>>
相关机构:河南中医学院第一附属医院广西医科大学浙江大学医学院附属邵逸夫医院更多>>
相关期刊:《Medicinal Plant》《当代医学》《World Journal of Gastroenterology》《World Journal of Gastrointestinal Pharmacology and Therapeutics》更多>>
相关基金:国家自然科学基金广西壮族自治区自然科学基金更多>>
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Mesalazine alleviated the symptoms of spontaneous colitis in interleukin-10 knockout mice by regulating the STAT3/NF-κB signaling pathway
《World Journal of Gastroenterology》2025年第7期88-97,共10页Qian Chen Ya-Li Zhang Yong-Quan Shi Lie Zheng 
Supported by Xi’an Science and Technology Plan Project,No.23YXYJ0162;Shaanxi Province Traditional Chinese Medicine Research and Innovation Talent Plan Project,No.TZKN-CXRC-16;Project of Shaanxi Administration of Traditional Chinese Medicine,No.SZYKJCYC-2025-JC-010;Shaanxi Province Key Research and Development Plan Project-Social Development Field,No.S2025-YF-YBSF-0391;the Science and Technology Innovation Cultivation Program of Longhua Hospital affiliated to Shanghai University of Chinese Medicine,No.YD202220。
BACKGROUND Excessive endoplasmic reticulum(ER)stress in intestinal epithelial cells can lead to damage to the intestinal mucosal barrier,activate the signal transducer and activator of transcription 3(STAT3)/nuclear f...
关键词:MESALAZINE Ulcerative colitis Interleukin-10-/-mice Signal transducer and activator of transcription 3/nuclear factor kappa B signaling pathway Endoplasmic reticulum stress Inflammatory bowel disease 
Infliximab is effective in the treatment of ulcerative colitis with dermatomyositis:A case report被引量:3
《World Journal of Gastroenterology》2020年第46期7425-7435,共11页Bin-Bin Huang Li-Chun Han Geng-Feng Liu Xiao-Dan Lv Guang-Li Gu Shi-Quan Li Lan Chen Hui-Qin Wang Ling-Ling Zhan Xiao-Ping Lv 
the National Natural Science Foundation of China,No.81860104 and 81460114;the Natural Science Foundation of Guangxi Zhuang Autonomous Region,No.2017GXNSFAA198299;the Development and Application of Medical and Health Appropriate Technology Project in Guangxi Zhuang Autonomous Region,No.S2018049;the Youth Science Foundation of Guangxi Medical University,No.GXMUYSF201913 and GXMUYSF201908;the Self-financing Project of Health Commission of Guangxi Zhuang Autonomous Region,No.Z20200398。
BACKGROUND Joint,skin,oral cavity,and eye lesions are the most common extraintestinal manifestations of ulcerative colitis that can occur before or after its onset.The cases of ulcerative colitis with dermatomyositis(...
关键词:Ulcerative colitis DERMATOMYOSITIS Extraintestinal manifestation INFLIXIMAB MESALAZINE Case report 
Gastroenterology case report of mesalazine-induced cardiopulmonary hypersensitivity被引量:5
《World Journal of Gastroenterology》2015年第13期4069-4077,共9页José Ferrusquía Isabel Pérez-Martínez Ricardo Gómez de la Torre María Luisa Fernández-Almira Ruth de Francisco Luis Rodrigo Sabino Riestra 
Mesalazine is a 5-aminosalicylic acid derivative that has been widely used to treat patients with inflammatory bowel disease. Accumulating evidence indicates that mesalazine has a very low rate of adverse drug reactio...
关键词:EOSINOPHILIA MESALAZINE PERICARDIAL EFFUSION Lung 
Proposed case of mesalazine-induced cardiomyopathy in severe ulcerative colitis被引量:9
《World Journal of Gastroenterology》2015年第11期3376-3379,共4页Kathryn Fleming Andrew Ashcroft Christopher Alexakis Demitrios Tzias Christopher Groves Andrew Poullis 
Supported by grants from NHS St Georges Hospital
Five-amino salicylic acids are recommended for use in the management of inflammatory bowel disease,cardiac complications are a rare although recognised phenomenon.This report aims to highlight this serious but rare ad...
关键词:ULCERATIVE COLITIS MESALAZINE Cardiomy-opathy Adve 
Microscopic colitis: A therapeutic challenge被引量:2
《World Journal of Gastroenterology》2013年第23期3531-3533,共3页Mario Guslandi 
The treatment of microscopic colitis is mainly based on the use of budesonide, the only drug found effective in controlled clinical trials. After an initial course at a dose of 9 mg daily, however, most patients relap...
关键词:MICROSCOPIC COLITIS BUDESONIDE MESALAZINE IMMUNOSUPPRESSANTS 
Mucosal healing effect of mesalazine granules in naproxen-induced small bowel enteropathy被引量:2
《World Journal of Gastroenterology》2013年第6期889-896,共8页István Rácz Milán Szalai Valéria Kovács Henriett Regczi Gyngyi Kiss Zoltán Horváth 
Supported by Dr.Falk Pharma GmbH,in part,study code:SAG-43/SBE
AIM:To investigate the effect of mesalazine granules on small intestinal injury induced by naproxen using capsule endoscopy (CE).METHODS:This was a single center,non-randomized,open-label,uncontrolled pilot study,usin...
关键词:NONSTEROIDAL anti-inflammatory drug Small bowel ENTEROPATHY MESALAZINE GRANULES Mucosal healing Capsule endoscopy 
A dynamic model of once-daily 5-aminosalicylic acid predicts clinical efficacy被引量:1
《World Journal of Gastroenterology》2010年第1期136-137,共2页Deepak Parakkal Eli D Ehrenpreis Matthew P Thorpe Karson S Putt Bruce Hannon 
New once daily mesalamine formulations may improve adherence to medication usage.Response to Asacol and other forms of 5-aminosalicyclic acid(5-ASA)is better correlated with tissue concentrations and best predicted by...
关键词:Ulcerative colitis 5-aminosalicylate MESALAZINE Asacol ONCE-DAILY 
Prevalence,predictors,and clinical consequences of medical adherence in IBD:How to improve it?被引量:5
《World Journal of Gastroenterology》2009年第34期4234-4239,共6页Peter Laszlo Lakatos 
Inflammatory bowel diseases(IBD)are chronic diseases with a relapsing-remitting disease course necessitating lifelong treatment.However,non-adherence has been reported in over 40%of patients,especially those in remiss...
关键词:Inflammatory bowel disease Crohn's disease Ulcerative colitis Therapy ADHERENCE Compliance 5-aminosalicylate MESALAZINE AZATHIOPRINE 
Use of new once-daily 5-aminosalicylic acid preparations in the treatment of ulcerative colitis:Is there anything new under the sun?被引量:3
《World Journal of Gastroenterology》2009年第15期1799-1804,共6页Peter Laszlo Lakatos 
5-aminosalicylate(5-ASA)agents remain the mainstay treatment in ulcerative colitis(UC).A number of oral 5-ASA agents are commercially available,including azobond pro-drugs,as well as delayed-and controlledrelease form...
关键词:Ulcerative colitis 5-aminosalicylate MESALAZINE Multi matrix system Therapy ONCE-DAILY Compliance 
Molecular basis of the potential of mesalazine to prevent colorectal cancer被引量:1
《World Journal of Gastroenterology》2008年第28期4434-4439,共6页Carmine Stolfi Roberto Pellegrini Eleonora Franzè Francesco Pallone Giovanni Monteleone 
Patients with ulcerative colitis (UC) and Crohn's disease (CD) are at increased risk for developing colorectal cancer (CRC), and this is believed to be a result of chronic inflammation. Although conclusive evidence is...
关键词:CHEMOPREVENTION Colorectal cancer CYCLOOXYGENASE-2 Epidermal growth factor receptor Inflammatory bowel disease MESALAZINE WNT/Β-CATENIN 
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