I’m writing to comment the article of Leung et al.entitled“Screening and identification of mimotopes of the major shrimp allergen tropomyosin using one-bead-one compound peptide libraries”appearing in this journal 1.
The one-bead-one-compound (OBOC) combinatorial peptide library is a powerful tool to identify ligand and receptor interactions. Here, we applied the OBOC library technology to identify mimotopes specific to the immu...
An mRNA display system using synthetic DNA cod-ing for random 10- and 20-amino-acid peptide li-braries was employed to isolate mimotopes that could substitute for the anti-human VEGF antibody Bevacizumab. After six ro...
supported by the National Natural Science Foundation of China(Grant No.30471596)
Hepatitis C (HCV) genome is highly variable, particularly in the hypervariable region 1 (HVR1) of its E2 envelope gene. The variability of HCV genome has been a major obstacle for developing HCV vaccines. Due to B-cel...
Supported by Natural Science Foundation of Guangdong Province, No. 970334
Objective: To screen and identify the mimotopes of lipopolysaccharide (LPS) epitope. Methods: A random phage display dodecapeptide library was screened with monoclonal antibody 2B4 specifically against LPS conservativ...