MITOCHONDRIAL

作品数:880被引量:2426H指数:17
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相关领域:医药卫生生物学更多>>
相关作者:戴朴王朝霞侯婷婷管敏鑫唐霄雯更多>>
相关机构:北京大学中国科学院中国人民解放军总医院中国科学院遗传与发育生物学研究所更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Corrigendum to“Actin polymerization induces mitochondrial distribution during collective cell migration”[Journal of Genetics and Genomics(2023)50 46-49]
《Journal of Genetics and Genomics》2023年第3期221-221,共1页Chen Qu Yating Kan Xinyi Wang Hui Zuo Mengqi Wu Zhixiang Dong Qing Zhang Heng Wang Dou Wang Jiong Chen 
This erratum clarifies information in the Letter to the Editor“Actin polymerization induces mitochondrial distribution during collective cell migration”by Qu et al.(2023).In the section for the list of author names,...
关键词:COLLECTIVE DISTRIBUTION MIGRATION 
Actin polymerization induces mitochondrial distribution during collective cell migration
《Journal of Genetics and Genomics》2023年第1期46-49,共4页Chen Qu Yating Kan Hui Zuo Mengqi Wu Zhixiang Dong Xinyi Wang Qing Zhang Heng Wang Dou Wang Jiong Chen 
supported by grants from the National Natural Science Foundation of China(31970743);the Fundamental Research Funds for the Central Universities(021414380524)to JC;grants from the National Natural Science Foundation of China(31900563);Natural Science Foundation of Jiangsu Province(BK20190303)to HW。
Collective cell migration plays critical roles in various developmental,physiological,and pathological processes such as morphogenesis,wound healing,and tumor metastasis(Friedl and Gilmour,2009).During collective migr...
关键词:HEALING COLLECTIVE WOUND 
Mitochondrial sirtuins,metabolism,and aging被引量:19
《Journal of Genetics and Genomics》2022年第4期287-298,共12页Zhejun Ji Guang-Hui Liu Jing Qu 
supported by the National Natural Science Foundation of China (91949209, 91749202, 92149301, 92168201);the National Key Research and Development Program of China (2018YFC2000100, 2020YFA0804000);the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA16010000);the National Natural Science Foundation of China (81921006, 81625009, 82125011);the Key Research Program of the Chinese Academy of Sciences (KFZD-SW-221);the 14th Five-year Network Security and Informatization Plan of Chinese Academy of Sciences (WX145XQ0718);Informatization Plan of Chinese Academy of Sciences (CASWX2021SF-0301);the Milky Way Research Foundation (MWRF)
Maintaining metabolic homeostasis is essential for cellular and organismal health throughout life.Multiple signaling pathways that regulate metabolism also play critical roles in aging,such as PI3K/AKT,mTOR,AMPK,and s...
关键词:Metabolism and aging regulation Mitochondrial sirtuins Aging-related diseases SIRT3 SIRT4 SIRT5 
Molecular insights into the transgenerational inheritance of stress memory被引量:1
《Journal of Genetics and Genomics》2022年第2期89-95,共7页Qian Zhang Ye Tian 
supported by the National Key R&D Program of China(2017YFA0506400);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB39000000);the National Natural Science Foundation of China(31930023,31771333);supported by the China National Postdoctoral Program for Innovative Talents(BX2021356)。
There is accumulating evidence to show that environmental stressors can regulate a variety of phenotypes in descendants through germline-mediated epigenetic inheritance. Studies of model organisms exposed to environme...
关键词:Transgenerational inheritance Environmental stress Epigenetic regulation Noncoding RNAs Mitochondrial DNA content Mitochondrial unfolded protein response (UPRmt) Soma-to-germline signaling 
Complexities and pitfalls in analyzing and interpreting mitochondrial DNA content in human cancer
《Journal of Genetics and Genomics》2020年第7期349-359,共11页Hieu Nguyen Thomas LaFramboise 
Mutations in the human mitochondrial genome have been observed in all types of human cancer,indicating that mutations might contribute to tumorigenesis,metastasis,recurrence,or drug response.This possibility is appeal...
关键词:Mitochondrial DNA Cancer Genetic variation 
Defective arginine metabolism impairs mitochondrial homeostasis in Caenorhabditis elegans被引量:3
《Journal of Genetics and Genomics》2020年第3期145-156,共12页Ruofeng Tang Xin Wang Junxiang Zhou Fengxia Zhang Shan Zhao Qiwen Gan Liyuan Zhao Fengyang Wang Qian Zhang Jie Zhang Guodong Wang Chonglin Yang 
supported by grants from the National Scicnce Foundation of China(91954204 and 31730053);the National Basic Research Program of China(2017YFA0503403)。
Arginine catabolism involves enzyme-dependent reactions in both mitochondria and the cytosol,defects in which may lead to hyperargininemia,a devastating developmental disorder.It is largely unknown if defective argini...
关键词:ARGININE ARGINASE Hyperargininemia Mitochondrial homeostasis C.elegans 
Human mitochondrial DNA diseases and Drosophila models被引量:2
《Journal of Genetics and Genomics》2019年第4期201-212,共12页Zhe Chen Fan Zhang Hong Xu 
supported by the intramural program at National Heart, Lung and Blood Institute
Mutations that disrupt the mitochondrial genome cause a number of human diseases whose phenotypic presentation varies widely among tissues and individuals. This variability owes in part to the unconventional genetics ...
关键词:MITOCHONDRIAL DNA MTDNA DISEASE MTDNA GENETICS DROSOPHILA model 
Novel DYW-type pentatricopeptide repeat(PPR) protein BLX controls mitochondrial RNA editing and splicing essential for early seed development of Arabidopsis被引量:2
《Journal of Genetics and Genomics》2018年第3期155-168,共14页Yan Sun Jiaying Huang Sheng Zhong Hongya Gu Shan He Li-Jia Qu 
supported by the National Natural Science Foundation of China(Nos.31620103903 and 31621001);partially by the 111 project;supported by the Peking-Tsinghua Joint Center for Life Sciences
In plants, RNA editing is a post-transcriptional process that changes specific cytidine to uridine in both mitochondria and plastids. Most pentatricopeptide repeat(PPR) proteins are involved in organelle RNA editing...
关键词:ARABIDOPSIS PPR RNA editing RNA splicing Embryo and endosperm development 
Mitochondrial replacement techniques or therapies (MRTs) to improve embryo development and to prevent mitochondrial disease transmission被引量:2
《Journal of Genetics and Genomics》2017年第8期371-374,共4页Xiang-Hong Ou Qing-Yuan Sun 
The mitochondrion which contains its own double-stranded circular DNA is a semi-independent organelle that plays critical roles in cell activity. Mitochondrial DNA (mtDNA) is maternally inherited through several mec...
关键词:mtDNA Mitochondrial replacement techniques or therapies to improve embryo development and to prevent mitochondrial disease transmission 
The Mitochondrial Genome of Raphanus sativus and Gene Evolution of Cruciferous Mitochondrial Types被引量:1
《Journal of Genetics and Genomics》2013年第3期117-126,共10页Shengxin Chang Jianmei Chen Yankun Wang Bingchao Gu Jianbo He Pu Chu Rongzhan Guan 
supported by the National Basic Research Program of China (973 Program) (No. 2011CB109300);the National Natural Science Foundation of China (No.30970289);the National Key Technology R&D Program (Nos.2010BAD01B02 and 2011BAD13B09) in China;the Special Fund for Independent innovation of Agricultural Science and Technology in Jiangsu province (Nos. CX (10)1030 and CX (11) 1026)
To explore the mitochondrial genes of the Cruciferae family, the mitochondrial genome of Raphanus sativus (sat) was sequenced and annotated. The circular mitochondrial genome of sat is 239,723 bp and includes 33 pro...
关键词:RADISH Mitochondrial genome EVOLUTION CRUCIFERAE 
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