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MITOCHONDRIAL_DNA: 作品数：251被引量：569H指数：10; 导出分析报告; 相关作者：张亚平程起群吴桂生李家乐沈玉帮更多>>; 相关机构：中国科学院上海海洋大学中国水产科学研究院东海水产研究所贵阳医学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>

Role of mitochondrial dysfunction in kidney disease:Insights from the cGAS-STING signaling pathway被引量：1: 《Chinese Medical Journal》2024年第9期1044-1053,共10页Lu Li Fei Liu Chunyue Feng Zhenjie Chen Nan Zhang Jianhua Mao; supported by a grant from the Zhejiang Provincial Natural Science Foundation of China(No.LY22H050002); Over the past decade,mitochondrial dysfunction has been investigated as a key contributor to acute and chronic kidney disease.However,the precise molecular mechanisms linking mitochondrial damage to kidney disease rem...; 关键词：Mitochondrial dysfunction Mitochondrial DNA cGAS-STING pathway Kidney diseases Chronic kidney disease

Circulating mitochondrial DNA levels are associated with early diagnosis and prognosis in patients with sepsis被引量：1: 《Chinese Medical Journal》2022年第23期2883-2885,共3页Gaosheng Zhou Jingjing Liu Hongmin Zhang Xiaoting Wang Dawei Liu; the Capital Clinic Research and Demonstration Application of Diagnosis and Treatment Project(No.Z201100005520038).; To the Editor:Both pathogen-associated molecular patterns and damage-associated molecular patterns(DAMPs)are known to enhance levels of inflammation and tissue injury during sepsis.Mitochondria are a major source of D...; 关键词：diagnosis SEPSIS PATIENTS

Brain atrophy in a patient with mitochondrial DNA G8363A mutation被引量：1: 《Chinese Medical Journal》2019年第17期2141-2142,共2页Hong-Liang Xu Ya-Jun Lian Xin Chen; To the Editor: Mitochondrial diseases are a common group of human genetic diseases that can occur at any decade of life. Mitochondrial DNA (mtDNA) mutations are responsible for most adult-onset mitochondrial diseases....; 关键词：There ARE In the LAST a large NUMBER of

Late-onset mitochondrial disease in a patient with MELAS and mitochondrial DNA T14487C mutation被引量：3: 《Chinese Medical Journal》2019年第6期716-718,共3页Xue-Bi Xu Kun-Qian Ji Jing-Wei Lyu Shu Zhang Xiao-Qing Lyu Chang Liu Wei Li Chuan-Zhu Yan Yu-Ying Zhao; grants from the National Natural Science Foundation of China (No. 81671235 and No. 81701237);People's Benefit Project of Science and Technology in Qingdao (No. 16-6-2-1-nsh) and the Taishan Scholars Program of Shandong Province.; To the Editor: Mitochondrial encephalomyopathy with lactate acidosis and stroke-like episodes (MELAS) is one of the most common multisystem mitochondrial disorders with broad clinical manifestations.[1] It is usually ...; 关键词：Editor Mitochondrial ENCEPHALOMYOPATHY LACTATE ACIDOSIS

Reference Intervals of Mitochondrial DNA Copy Number in Peripheral Blood for Chinese Minors and Adults被引量：2: 《Chinese Medical Journal》2017年第20期2435-2440,共6页Chang-Yu Xia Yu Liu Hui-Rong Yang Hong-Yun Yang Jing-Xia Liu Yi-Nan Ma Yu Qi; This study was supported by grants from the National Natural Science Foundation of China （No. 81271256 and No. 81471153） and Beijing Municipal Science and Technology Commission （No. Z 131107002213062）.; Background： Mitocbondrial DNA （mtDNA） content measured by different techniques cannot be compared between studies, and age- and tissue-related control values are hardly available. In the present study, we aimed to ...; 关键词：Mitochondrial Depletion Syndromes Mitochondrial Disease： Mitochondrial DNA： Reference Range

A Mitochondrial DNA A8701G Mutation Partly Associated with Maternally Inherited Hypertension and Dilated Cardiomyopathy in a Chinese Pedigree: 《Chinese Medical Journal》2016年第15期1890-1890,共1页Ye Zhu Xiang Gu Chao Xu; Thank you for your valuable comments on our paper, ＂A Mitochondrial DNAA8701G Mutation Associated with Maternally Inherited Hypertension and Dilated Cardiomyopathy in a Chinese Pedigree.＂We agree with this conclusio...

Clinical and Molecular Characteristics in 100 Chinese Pediatric Patients with m.3243A〉G Mutation in Mitochondrial DNA被引量：4: 《Chinese Medical Journal》2016年第16期1945-1949,共5页Chang-Yu Xia Yu Liu Hui Liu Yan-Chun Zhang Yi-Nan Ma Yu Qi; This study was supported by grants from National Natural Science Foundation of China （No. 81271256 and No. 81471153） and the Capital Characteristic Clinical Application Research Projects （No. Z 1311070022 13062）.; Background： Mitochondrial diseases are a group of energy metabolic disorders with multisystem involvements. Variable clinical features present a major challenge in pediatric diagnoses. We summarized the clinical spec...; 关键词：Clinical Symptom HETEROPLASMY Mitochondrial A3243G Mutation Mitochondrial Disease

A Mitochondrial DNA A8701G Mutation Associated with Maternally Inherited Hypertension and Dilated Cardiomyopathy in a Chinese Pedigree of a Consanguineous Marriage被引量：4: 《Chinese Medical Journal》2016年第3期259-266,共8页Ye Zhu Xiang Gu Chao Xu; Background： Cardiovascular diseases, including dilated cardiomyopathy （DCM） and hypertension, are the leading cause of death worldwide.The role of mitochondrial DNA （mtDNA） in the pathogenesis of these diseases h...; 关键词：Dilated Cardiomyopathy HYPERTENSION MITOCHONDRIA Mitochondrial DNA Mutation

Mitochondrial DNA Haplogroups and the Risk of Sporadic Parkinson＇s Disease in Han Chinese被引量：4: 《Chinese Medical Journal》2015年第13期1748-1754,共7页Ya-Fang Chen Wan-Jin Chen Xiao-Zhen Lin Qi-Jie Zhang Jiang-Ping Cai Chia-Wei Liou Ning Wang; This work was supported by the grant 81322017 from the National Natural Science Foundation of China, grant NCET-13-0736 from Program for New Century Excellent Talents in University, National Key Clinical Specialty Discipline Construction Program and Key Clinical Specialty Discipline Construction Program of Fujian.; Background： Mitochondrial dysflmction is linked to the pathogenesis of Parkinson＇s disease （PD）. However, the precise role of mitochondrial DNA （mtDNA） variations is obscure. On the other hand, mtDNA haplogroups...; 关键词：l-tan Chinese HAPLOGROUPS Mitochondrial DNA Parkinson＇s Disease

Single nucleotide polymorphisms in the D-loop region of mitochondrial DNA and age-at-onset of patients with chronic kidney disease被引量：1: 《Chinese Medical Journal》2014年第17期3088-3091,共4页Bai Yaling Guo Zhanjun Xu Jinsheng Zhang Junxia Cui Liwen Zhang Huiran Zhang Shenglei Ai Xiaolu; Background The mitochondrial displacement loop （D-loop） accumulates mutations and single nucleotide polymorphisms （SNPs） at a higher frequency than other regions of mitochondrial DNA （mtDNA）.We previously identi...; 关键词：D-loop peptide chronic kidney disease single nucleotide polymorphism mitochondrial DNA

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