This work was supported by the National Key R&D Program of China(2018YFA0107001);the National Natural Science Foundation of China(31671403 and 31701169).
Cilia are hair-like organelles that protrude from the surface of many types of eukaryotic cells.Each cilium possesses a microtubule-based central core,known as the axoneme,surrounded by the ciliary membrane.Ciliogenes...
Mitosis is a highly dynamic cellular event that involves high energy consumption and active membrane remodeling.Autophagy is a process that cells digest their cellular contents to provide energy and nutrients to maint...
This work was supported by the State Key Basic Research Program of China (Grant No. G1999053906).
Fibrillann, a major protein in the nucleolus. is known to redistribute during mitosis from the nucleolus to the cytosol, and is related to the dynamics of post-mitotic reassembly of the nucleolus. To better understand...
IN the late 1970s, biochemical analysis and electron microscopy of isolated, histone-depleted mitotic chromosomes demonstrated the existence of a central scaffold consisting mainly of nonhistone proteins (NHPs) in met...
Project supported by the National Natural Science Foundation of China.
Nuclear matrix is an insoluble proteinaceous filament network in nucleus. Numerous research works demonstrated that many important life activities, such as DNA replication, RNA transcription and processing, chromatin ...