supported by the Natural Science Foundation of Anhui Province(1508085J06,1608085QA02);the Key Projects for Academic Talent of Anhui Province(gxbjZD2016005);the Science Research Project of Chuzhou University(2015GH35);the Quality Engineering Project of Anhui Province(2015jyxm045);the Quality Improvement Project for Undergraduate Education of Anhui University(ZLTS2015035)