supported by National Natural Science Foundation of China (Grant Nos 30630029 and 30621062);the National Basic Research Program of China (Grant Nos 2006CB806604 and 2009CB52205);the Konowledge Innovation Program of the Chinese Academy of Sciences (Grant No KSCXZ-YW-R-31)
In addition to investigating the anatomy,neurochemistry and neurophysiology of pain pathways,Chinese researchers have extended their work into the molecular and cellular mechanisms of sensory afferent transmission at ...
the Deutsche Forschungsgemeinschaft(DFG Grant 954/3-1)as a part of the priority program 1608“Ultrafast and temporally precise information processing:normal and dysfunctional hearing”。
Purinergic P2 receptors,activated by endogenous ATP,are prominently expressed on neuronal and nonneuronal cells during development of the auditory periphery and central auditory neurons.In the mature cochlea,extracell...
supported by the National Natural Science Foundation of China,No.82271114;the Natural Science Foundation of Zhejiang Province of China,No.LZ22H120001(both to ZLC).
Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured neurons.However,a poor integration rate and high risk of tumorigenicity after cell transplantation limit...
supported by the National Natural Science Foundation of China (81701092);Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Support (20171916);Shanghai Municipal Commission of Health and Family Planning Funding for Key Developing Disciplines (2015ZB0101)
High-voltage-activated(HVA) Ca^(2+)channels are widely expressed in the nervous system. They play an important role in pain conduction by participating in various physiological processes such as synaptic transmission,...
Supported by the Ministry of Science and Technology of China(No.2021ZD0203104);the Science and Technology Plan Project of Shaanxi Province of China(No.2022SF-497);Xi’an Medical University Doctoral Research Fund(No.2020DOC18).
AIM:To determine whether etomidate(ET)has a protective effect on retinal ganglion cells(RGCs)injured with hydrogen peroxide(H_(2)O_(2))and to explore the potential mechanism underlying the antioxidative stress effect ...
Glaucoma is a group of degenerative retinal diseases that damage the eye’s optic nerve and can result in vision loss and blindness.It is characterized by optic neuropathy,cupping of the optic disk.
supported by The National Natural Science Foundation of China(No.81670894,81721003,81570862,82000915);The National Key Research and Development Program of China(No.2020YFA0112701);The Pearl River Talents Program-Local Innovative and Research Teams(No.2017BT01S138);The“100 talents plan”from Sun Yat-sen University;the Open Research Funds of the State Key Laboratory of Ophthalmology(No.2022KF04);The Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science(No.2017B030314025);The NSFC/Macao Science and Technology Development Fund(No.015/2017/AFJ to KZ);the Fundamental Research Funds for the Central Universities,Sun Yat-sen University(No.22qntd3902).
Glaucoma is the leading cause of irreversible blindness worldwide.In the pathogen-esis of glaucoma,activated microglia can lead to retinal ganglion cells(RGCs)apoptosis and death,however,the molecular mechanisms remai...
BACKGROUND Awake fiberoptic nasotracheal intubation(AFNI)is the preferred airway ma-nagement strategy for patients with difficult airways.However,this procedure can cause significant physical and psychological distres...
funded by the Biotechnology and Biological Sciences Research Council(BBSRC),No.BB/F017553/1
In this perspective,we discuss the use of an anti-fibrotic agent Decorin to treat established fibrosis associated with glaucoma originally published by Hill et al.(2015).Glaucoma describes a group of progressive opt...
Supported by National Natural Science Foundation of China(No.81800879);Natural Science Foundation of Guangdong Province(No.2017A030310372);Fundamental Research Funds of the State Key Laboratory of Ophthalmology,China(No.2018KF04; No.2017QN05);Sun Yat-Sen University Clinical Research 5010 Program(No.2014016)
AIM: To evaluate the patterns of macular ganglion cell-inner plexiform layer(GCIPL) loss in normal tension glaucoma(NTG) and primary open angle glaucoma(POAG) in a detailed, disease severity-matched way;and to assess ...