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Neuroprotective effects of willed-movement therapy in a rat model of cerebral ischemia/reperfusion被引量:1
《Neural Regeneration Research》2011年第35期2756-2760,共5页Deren Hou Jianfeng Liu Jinfeng Deng Zhongyang Hu Chao Feng Haixia Zhu 
the Science and Technology Projects from Science and Technology Agency,Hunan Province,China,No. 2011FJ3206
The present study established rat models of middle cerebral artery ischemia/reperfusion using the thread method. Rats performed willed-movement (climbing a ladder or wall in a box) when induced by food and water. Re...
关键词:cerebral ischemia/reperfusion glial fibrillary acidic protein growth-associated protein 43 neural regeneration willed-movement neurotrophic factor-3 
Combination of epidural electrical stimulation with ex vivo triple gene therapy for spinal cord injury:a proof of principle study被引量:4
《Neural Regeneration Research》2021年第3期550-560,共11页Filip Olegovich Fadeev Farid Vagizovich Bashirov Vahe Arshaluysovich Markosyan Andrey Alexandrovich Izmailov Tatyana Vyacheslavovna Povysheva Mikhail Evgenyevich Sokolov Maxim Sergeevich Kuznetsov Anton Alexandrovich Eremeev Ilnur Ildusovich Salafutdinov Albert Anatolyevich Rizvanov Hyun Joon Lee Rustem Robertovich Islamov 
supported by the grant of Russian Science Foundation,No.16-15-00010(to RRI);supported by the Russian Government Program of Competitive Growth of Kazan Federal University。
Despite emerging contemporary biotechnological methods such as gene-and stem cell-based therapy,there are no clinically established therapeutic strategies for neural regeneration after spinal cord injury.Our previous ...
关键词:adenoviral vector epidural electrical stimulation gene therapy glial cell-line derived neurotrophic factor human umbilical cord blood mononuclear cell neural cell adhesion molecule spinal cord injury vascular endothelial growth factor 
Promotion of axon regeneration and inhibition of astrocyte activation by alpha A-crystallin on crushed optic nerve被引量:2
《International Journal of Ophthalmology(English edition)》2016年第7期955-966,共12页Wei-Yang Shao Xiao Liu Xian-Liang Gu Xi Ying Nan Wu Hai-Wei Xu Yi Wang 
Supported by the National Nature Science Foundation of China(No.81270996)
AIM:To explore the effects of αA-crystallin in astrocyte gliosis after optic nerve crush(ONC) and the mechanism of α-crystallin in neuroprotection and axon regeneration.METHODS:ONC was established on the Sprague...
关键词:αA-crystallin axonal regeneration astrocyte glial scar chondroitin sulfate proteoglycans optic nerve crush 
A Rare Case of Nasal Glial Heterotopia Presenting as Sphenochoanal Polyp
《International Journal of Otolaryngology and Head & Neck Surgery》2015年第2期77-80,共4页Pavol Surda Jonathan Hobson 
Objective: This paper reports a rare case of nasal glial heterotopia presenting as sphenochoanal polyp. So far, literature has revealed only few cases. Case Report: A 55-year-old woman presented with a 2-month history...
关键词:HETEROTOPIC GLIAL HETEROTOPIA SPHENOID Sinus NASAL Cavity Sphenochoanal POLYP 
CID 1067700, a late endosome GTPase Rab7 receptor antagonist, attenuates brain atrophy, improves neurologic deficits and inhibits reactive astrogliosis in rat ischemic stroke被引量:3
《Acta Pharmacologica Sinica》2019年第6期724-736,共13页Yuan Qin Yang He Yong-ming Zhu Min Li Yong Ni Jin Liu Hui-ling Zhang 
National Natural Science Foundation of China (No 30973510, 81171104, 81473211);Jiangsu Key Laboratory of Neuropsychiatric Diseases (No BM2013003);Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, and a project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).
Increasing evidence suggests that Ras-related in brain 7 (Rab7), an endosome-localized small GTPase contributes to cerebral ischemic brain injury. In the present study, we investigated the role of Rab7 in ischemic str...
关键词:ischemic stroke ASTROCYTES Rab7 CID1067700 GLIAL scar LYSOSOME 
Exosomes as mediators of neuron-glia communication in neuroinflammation被引量:14
《Neural Regeneration Research》2020年第5期796-801,共6页María Pascual Francesc Ibánez Consuelo Guerri 
supported by grants from the Health Ministry,PNSD(2018-I003);Institute Carlos III and FEDER funds(RTA-Network,RD16 0017 0004);Spanish Ministry of Science and Innovation(SAF2015-69187R);FEDER Funds,Generalitat Valenciana
In recent years,a type of extracellular vesicles named exosomes has emerged that play an important role in intercellular communication under physiological and pathological conditions.These nanovesicles (30–150 nm) co...
关键词:biomarkers EXOSOMES glial cells NEUROINFLAMMATION neuron-glia commuication neurons NEUROPATHOLOGY therapy 
Protein post-translational modifications after spinal cord injury被引量:3
《Neural Regeneration Research》2021年第10期1935-1943,共9页Shuang Zhu Bing-Sheng Yang Si-Jing Li Ge Tong Jian-Ye Tan Guo-Feng Wu Lin Li Guo-Li Chen Qian Chen Li-Jun Lin 
This work was supported by the National Natural Science Foundation of China,No.81801210(to SZ).
Deficits in intrinsic neuronal capacities in the spinal cord,a lack of growth support,and suppression of axonal outgrowth by inhibitory molecules mean that spinal cord injury almost always has devastating consequences...
关键词:extracellular matrix function impairment glial scar nerve regeneration neuropathic pain post-translational modification spinal cord injury therapeutic target 
Establishment and expression of recombinant human glial cell linederived neurotrophic factor and TNF α receptor in human neural stem cells被引量:2
《Asian Pacific Journal of Tropical Medicine》2012年第8期651-655,共5页Ke-Xiong Zhuang Wei Huang Bin Yan 
Shenzhen Science and Technology Project(No.201103061)
Objective:To investigate the interference and expression of human glial cell line-derived neurotrophic factor(hCDNF) and soluble TNF alpha(sTMFRⅠ) receptor genes in neural stem cells and to evaluate the roles of thes...
关键词:GLIAL cell line-derived NEUROTROPHIC FACTOR Tumor NECROSIS FACTOR receptorⅠ Neural stem cells Gene therapy 
Effects of P2Y_1 receptor on glial fibrillary acidic protein and glial cell line-derived neurotrophic factor production of astrocytes under ischemic condition and the related signaling pathways被引量:3
《Neuroscience Bulletin》2008年第4期231-243,共13页孙景军 刘颖 叶诸榕 
the National Natural Science Foundation of China (No. 30500189)
Objective The present study aimed to explore the role of P2Y1 receptor in glial fibrillary acidic protein (GFAP) production and glial cell line-derived neurotrophic factor (GDNF) secretion of astrocytes under isch...
关键词:P2Y1 receptor GLIOSIS glial fibrillary acidic protein glial cell line-derived neurotrophic factor PI3-K/Akt/CREB JAK2/STAT3 Ras/ERK 
Regional brain susceptibility to neurodegeneration: what is the role of glial cells?被引量:4
《Neural Regeneration Research》2020年第5期838-842,共5页Andrea Beatriz Cragnolini Giorgia Lampitella Assunta Virtuoso Immacolata Viscovo Fivos Panetsos Michele Papa Giovanni Cirillo 
supported by grants from Regione Campania(L.R.N.5 Bando 2003,to MP);the Italian Minister of Research and University(PRIN 2007,to MP; PRIN 2017,to GC and MP);UNIMIB(Progetto ID 2019-ATESP-0001 and Progetto ID 2018-CONV-0056,to AV)
The main pathological feature of the neurodegenerative diseases is represented by neuronal death that represents the final step of a cascade of adverse/hostile events.Early in the neurodegenerative process,glial cells...
关键词:ASTROCYTES GLIAL cells microglia NEURODEGENERATIVE diseases neuroinflammation Parkinson's disease reactive GLIOSIS selective neuronal degeneration 
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