国家自然科学基金(YZ)

作品数：16被引量：97H指数：5
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Collagen-based materials in reproductive medicine and engineered reproductive tissues被引量：3
《Journal of Leather Science and Engineering》2022年第1期37-51,共15页Hanxiao Chen Luqi Xue Guidong Gong Jiezhou Pan Xiaoling Wang Yaoyao Zhang Junling Guo Lang Qin 
the Sichuan Science and Technology Program(L.Q.,Grant No.2020YFS0127);the Y.Z.laboratory was financially supported by the Research project of Science&Technology Department of Sichuan Province(Y.Z.,Grant No.2021YJ0416);project of Chengdu Science and Technology Bureau,(Y.Z.,Grant No.2021-YF05-02110-SN)National Natural Science Foundation of China(Y.Z.,Grant No.82001496);China Postdoctoral Science Foundation(Y.Z.,Grant No.2020M680149,2020T130087ZX);the National Global Talents Recruitment Program(J.G.),National Natural Science Foundation of China(22178233);Talents Program of Sichuan Province,Double First Class University Plan of Sichuan University,State Key Laboratory of Polymer Materials Engineering(J.G.,Grant No.sklpme 2020-3-01).
Collagen,the main component of mammal skin,has been traditionally used in leather manufacturing for thousands of years due to its diverse physicochemical properties.Collagen is the most abundant protein in mammals and...
关键词：Collagen-based biomaterials Leather and collagen Leather tanning process Reproductive medicine Reproductive tissues 
The role of extracellular matrix on unfavorable maternal-fetal interface:focusing on the function of collagen in human fertility被引量：2
《Journal of Leather Science and Engineering》2022年第1期184-200,共17页Rang Liu Mengyuan Dai Guidong Gong Mei Chen Canhui Cao Tianren Wang Zhenhui Hou Yu Shi Junling Guo Yaoyao Zhang Xi Xia 
the Research project of Science&Technology Department of Sichuan Province(Y.Z.,Grant No.2021YJ0416);project of Chengdu Science and Technology Bureau,(Y.Z.,Grant No.2021-YF05-02110-SN);National Natural Science Foundation of China(Y.Z.,Grant No.82001496);China Postdoctoral Science Foundation(Y.Z.,Grant No.2020M680149,2020T130087ZX);China Postdoctoral Science Foundation(C.C.,Grant No.2021M702223);Shenzhen Science and Technology Innovation Committee(C.C.,Grant No.JCYJ20210324105808022);the Research Team of Female Reproductive Health and Fertility Preservation(W.Q.,Grant No.SZSM201612065).
Extracellular matrix(ECM)is characterized as widespread,abundant,and pluripotent.Among ECM members,collagen is widely accepted as one of the most prominent components for its essential structural property that can pro...
关键词：Collagen Extracellular matrix(ECM) Matrix metalloproteinases(MMPs) ENDOMETRIUM Maternal-fetal interface INFERTILITY 
Defining newly formed and tissue-resident bone marrow-derived macrophages in adult mice based on lysozyme expression
《Cellular & Molecular Immunology》2022年第12期1333-1346,共14页Tong Lei Jiayu Zhang Qian Zhang Xinran Ma Yanan Xu Yang Zhao Lianfeng Zhang Zhongbing Lu Yong Zhao 
supported by grants from the National Natural Science Foundation for Key Programs (31930041,Y.Z.);National Key Research and Development Program of China (2017YFA0105002,2017YFA0104402,Y.Z.);Knowledge Innovation Program of the Chinese Academy of Sciences (XDA16030301,Y.Z.).
Tissue-resident macrophages are derived from different precursor cells and display different phenotypes.Reconstitution of the tissue-resident macrophages of inflamed or damaged tissues in adults can be achieved by bon...
关键词：Tissue-resident macrophages Kupffer cells LYSOZYME Inflammation Metabolism CYTOKINE 
Two kinds of macrophage memory:innate and adaptive immune-like macrophage memory被引量：1
《Cellular & Molecular Immunology》2022年第7期852-854,共3页Changhong Wu Yanan Xu Yong Zhao 
This work was supported by grants from the National Natural Science Foundation for Key Programs(31930041,YZ);Knowledge Innovation Program of the Chinese Academy of Sciences(XDA16030301,YZ);National Key Research and Development Program of China(2017YFA0105002,2017YFA0104402,YZ).
It is believed that the adaptive immune system responds to nonself entities with its specificity and memory properties.In contrast,the innate immune system lacks adaptive characteristics.Whether innate immune cells ca...
关键词：PROPERTIES CHARACTERISTICS system 
What group 2 innate lymphoid cells tell themselves:autocrine signals play essential roles in mucosal immunity被引量：1
《Signal Transduction and Targeted Therapy》2021年第8期2264-2265,共2页Yang Zhao Wenxian Guan Xiaofei Shen 
This work was supported by the National Natural Science Foundation of China(number 81970500,X.S.,number 81802846,YZ.);the Natural Science Foundation of Jiangsu Province(SBK2018040809,YZ.).
Recently,two article papers(Chu et al.1 and Roberts et al.2)were published describing that autocrine regulation mediated by the choline acetyltransferase(ChAT)-acetylcholine(ACh)is critical for optimal Group 2 innate ...
关键词：IMMUNITY LYMPHOID 
Spaceflight and simulated microgravity suppresses macrophage development via altered RAS/ERK/NFκB and metabolic pathways被引量：10
《Cellular & Molecular Immunology》2021年第6期1489-1502,共14页Lu Shi Hongling Tian Peng Wang Ling Li Zhaoqi Zhang Jiayu Zhang Yong Zhao 
supported by grants from the National Key Research and Development Program of China(2017YFA0105002,Y.Z.2017YFA0104402,L.L.);Joint Funds of the National Natural Science Foundation of China(U1738111,Y.Z.);the China Manned Space Flight Technology Project(TZ-1);the National Natural Science Foundation Youth Fund(31800741,L.S.).
Spaceflight-associated immune system weakening ultimately limits the ability of humans to expand their presence beyond the earth's orbit. A mechanistic study of microgravity-regulated immune cell function is necessary...
关键词：MICROGRAVITY Hematopoietic progenitor cells Macrophage differentiation Macrophage polarization RAS/ERK/NFκB pathway 
Primed macrophages gain long-term specific memory to reject allogeneic tissues in mice被引量：5
《Cellular & Molecular Immunology》2021年第4期1079-1081,共3页Zhulang Chu Chang Feng Chenming Sun Yanan Xu Yong Zhao 
supported by grants from the National Key R&D Program of China(2017YFA0105002,2017YFA0104402,Y.Z.);the Chinese Government 13th Five-Year Plan(2017ZX10201101);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16030301,Y.Z.);the National Natural Science Foundation for General and Key Programs(C81530049,C81130055,C31470860,U1738111,Y.Z.);the Fundamental Research Funds for the Central Universities(2018-JYBZZ-XJSJJ004,Z.C.).
It is believed that the adaptive immune system responds to nonself according to its specificity and memory properties,whereas the innate immune system lacks adaptive characteristics.The specificity of the adaptive imm...
关键词：characteristics. SPECIFIC SPECIFICITY 
Fine-Grained Binary Analysis Method for Privacy Leakage Detection on the Cloud Platform被引量：1
《Computers, Materials & Continua》2020年第7期607-622,共16页Jiaye Pan Yi Zhuang Xinwen Hu Wenbing Zhao 
This work is supported by the National Natural Science Foundation of China(General Program,Grant No.61572253,YZ,http://www.nsfc.gov.cn);the Innovation Program for Graduate Students of Jiangsu Province,China(Grant No.KYLX16_0384,JP,http://jyt.jiangsu.gov.cn).
Nowadays cloud architecture is widely applied on the internet.New malware aiming at the privacy data stealing or crypto currency mining is threatening the security of cloud platforms.In view of the problems with exist...
关键词：Cloud platform privacy leakage binary analysis dynamic analysis 
PGC-1α overexpression promotes mitochondrial biogenesis to protect auditory cells against cisplatin-induced cytotoxicity
《Journal of Bio-X Research》2019年第2期81-86,共6页Weijian Zhang Hao Xiong Jiaqi Pang Lan Lai Zhongwu Su Hanqing Lin Bingquan Jian Haidi Yang Yiqing Zheng 
supported by the Project funded by China Postdoctoral Science Foundation(No.2018M640863 to JP);the National Natural Science Foundation of China(No.81771018,81570935,81570916,and 81873699 to HX and YZ);the Guangdong Natural Science Foundation of China(No.2015A030313084 and 2017A030313585 to HX);Yixian Research Launch Project of China(No.YXQH201807 to HX).
Cisplatin(CDDP)-induced ototoxicity is one of the common adverse effects of cisplatin chemotherapy.Thus far,effective approaches for attenuating hearing loss are unavailable in clinical practice.Mitochondrial biogenes...
关键词：PGC-1a CISPLATIN mitochondrial biogenesis survival cell death ZLN005 therapy HEI-OC1 cells 
IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis被引量：22
《Protein & Cell》2018年第12期1027-1038,共12页Yuzhu Hou Linnan Zhu Hongling Tian Hai-Xi Sun Ruoyu Wang Lianfeng Zhang Yong Zhao 
the National Natural Science Foundation for General and Key Programs (C81530049,C81130055,C31470860,Y.Z.);Knowledge Innovation Program of Chinese Academy of Sciences (XDA04020202-19,Y.Z.).
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