国家自然科学基金(Beijing)

作品数：26被引量：61H指数：5
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Metabolic utilization of intravenously injected iron from different iron sources in target tissues of broiler chickens被引量：2
《Animal Nutrition》2022年第2期74-83,共10页Lin Lu Xueyu Dong Xuelian Ma Liyang Zhang Sufen Li Xugang Luo Xiudong Liao 
the National Natural Science Foundation of China(project number 31672440,Beijing,China);the Research Program of State Key Laboratory of Animal Nutrition(project number 2004DA125184G1606,Beijing,China);the Agricultural Science and Technology Innovation Program(ASTIP-IAS09,Beijing,China);the China Agriculture Research System of MOF and MARA(project number CARS-41,Beijing,China).
No information is available regarding the utilization of iron (Fe) from different Fe sources at a targettissue level. To detect differences in Fe metabolic utilization among Fe sources, the effect of intravenouslyinje...
关键词：Intravenous injection Iron-containing protein Gene expression Iron source BROILER 
Regulation of bone phosphorus retention and bone development possibly by related hormones and local bone-derived regulators in broiler chicks被引量：2
《Journal of Animal Science and Biotechnology》2022年第1期224-239,共16页Sumei Cao Tingting Li Yuxin Shao Liyang Zhang Lin Lu Rijun Zhang Shuisheng Hou Xugang Luo Xiudong Liao 
supported by the Key Program of the National Natural Science Foundation of China(project no.31630073,Beijing,P.R.China);the National Key R&D Program of China(project no.2017YFD0502200,Beijing,P.R.China);the China Agriculture Research System of MOF and MARA(project no.CARS-41,Beijing,P.R.China);the Agricultural Science and Technology Innovation Program(project no.ASTIPIAS09,Beijing,P.R.China).
Background:Phosphorus is essential for bone mineralization in broilers,however,the underlying mechanisms remain unclear.We aimed to investigate whether bone phosphorus retention and bone development might be regulated...
关键词：BONE Broiler chicken Hormone Local bone-derived regulator PHOSPHORUS 
Zinc alleviates the heat stress of primary cultured hepatocytes of broiler embryos via enhancing the antioxidant ability and attenuating the heat shock responses被引量：5
《Animal Nutrition》2021年第3期621-630,共10页Tingting Li Wengang He Xiudong Liao Xi Lin Liyang Zhang Lin Lu Yanli Guo Zongping Liu Xugang Luo 
supported by the Key International Cooperation Program of the National Natural Science Foundation of China(project no.31110103916,Beijing,China);the National Natural Science Foundation of China(project no.31972583,Beijing,China);the China Agricultural Research System(project no.CARS-41,Beijing,China);the Agricultural Science and Technology Innovation Program(ASTIP-IAS09,Beijing,China)
Zinc(Zn)has been shown to attenuate the adverse effects of heat stress on broilers,but the mechanisms involving this process remain unclear.We aimed to investigate possible protective mechanisms of Zn on primary cultu...
关键词：Broiler hepatocyte ZINC Heat stress Antioxidant ability Heat shock response 
Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies被引量：5
《Cell Research》2021年第5期517-525,共9页Renhong Yan Ruoke Wang Bin Ju Jinfang Yu Yuanyuan Zhang Nan Liu Jia Wang Qi Zhang Peng Chen Bing Zhou Yaning Li Yaping Shen Shuyuan Zhang Long Tian Yingying Guo Lu Xia Xinyue Zhong Lin Cheng Xiangyang Ge Juanjuan Zhao Hong-Wei Wang Xinquan Wang Zheng Zhang Linqi Zhang Qiang Zhou 
We thank the cryo EM facility and the supercomputer center of Westlake University and the cryo-EM facility and the bio-computing platform at Tsinghua University Branch of China National Center for Protein Sciences(Beijing)for providing cryo-EM and computation supports.This work was funded by the National Natural Science Foundation of China(projects 32022037,82025022,31971123,81920108015,31930059,81530065,91442127,82002140);the SARS-CoV-2 emergency project of the Science and Technology Department of Zhejiang Province(2020C03129);the Key R&D Program of Zhejiang Province(2020C04001);the Beijing Advanced Innovation Center for Structural Biology and the National Key Plan for Scientific Research and Development of China(2020YFC0848800,2020YFC849900,2020YFC0844200);the Science and Technology Innovation Committee of Shenzhen Municipality(202002073000002,2020A1111350032,JCYJ20190809115617365,and 2020B1111340074);the Natural Science Foundation of Guangdong Province of China(2019A1515011197);Beijing Municipal Science and Technology Commission(Z201100005420019 and 171100000517);the Leading Innovative and Entrepreneur Team Introduction Program of Hangzhou,and Special Research Program of Novel Coronavirus Pneumonia of Westlake University and Tencent Foundation,Tsinghua University Spring Breeze Fund(2020Z99CFG004);The China Postdoctoral Science Foundation(2020M681937 to R.Y);the National Postdoctoral Program for Innovative Talents of China(BX20200304 to R.Y).
Neutralizing monoclonal antibodies(nAbs)to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)represent promising candidates for clinical intervention against coronavirus disease 2019(COVID-19).We isolated a l...
关键词：ANTIBODIES NEUTRAL RESPIRATORY 
Green tea polyphenols supplementation alters immunometabolism and oxidative stress in dairy cows with hyperketonemia被引量：8
《Animal Nutrition》2021年第1期206-215,共10页Yanfen Ma Ying Feng Liwen Song Muyang Li Hongyu Dai Hua Bao Guijie Zhang Lei Zhao Chunhua Zhang Jing Yi Yusheng Liang 
grants from National Natural Science Foundation of China(no.32060765,31601975,31460616,Beijing,China);Inner Mongolia Natural Science Foundation of China(no.2019BS03033,Hohhot,China);Ningxia University Scientific Research Start-up Project,Inner Mongolia Academy of Agricultural&Animal Husbandry Science Innovation Foundation(no.2018QNJJM08,2019GXJJM06,Hohhot,China);Inner Mongolia Autonomous Region Foundation for Innovation Initiation Support Program for Overseas Students(Hohhot,China);Inner Mongolia Autonomous Region Ministry of Finance Agricultural and husbandry Science and Technology Promotion Project(no.2020TG07-6,Hohhot,China).
Peripartal cows often experience negative energy balance,and are therefore prone to suffering from metabolic diseases such as hyperketonemia,which causes financial losses in dairy farms.This study aimed to investigate...
关键词：Green tea polyphenol Hyperketonemia Peripartal period Dairy cow 
Removal of nonimpacted third molars alters the periodontal condition of their neighbors clinically, immunologically, and microbiologically被引量：4
《International Journal of Oral Science》2021年第1期52-61,共10页Yi Tian Lijuan Sun Honglei Qu Yang Yang Faming Chen 
supported by the Major Research Program of the National Natural Science Foundation of China(Beijing,Subproject No.81991503);the Changjiang Scholars Program of the Ministry of Education of the People’s Republic of China(2016).
Considering the adverse effects of nonimpacted third molars(N-M3s)on the periodontal health of adjacent second molars(M2s),the removal of N-M3s may be beneficial to the periodontal health of their neighbors.This study...
关键词：PERIODONTAL MOLAR CONDITION 
Lens thickness and associated ocular biometric factors among cataract patients in Shanghai被引量：4
《Eye and Vision》2021年第1期214-222,共9页Jiaqi Meng Ling Wei Wenwen He Jiao Qi Yi Lu Xiangjia Zhu 
The Chinese National Natural Science Foundation(grant nos.81970780,81870642,81670835,Beijing,China);the Shanghai Talent Development Fund(grant no.201604,Shanghai,China);the Outstanding Youth Medical Talents Program of Shanghai Health and Family Planning Commission(grant no.2017YQ011,Shanghai,China).
Background:To evaluate the distribution of lens thickness(LT)and its associations with other ocular biometric factors among cataract patients in Shanghai.Methods:Twenty-four thousand thirteen eyes from 24,013 cataract...
关键词：Lens thickness CATARACT Ocular biometry Axial length 
The associations of lens power with age,axial length and type 2 diabetes mellitus in Chinese adults aged 50 and above
《Eye and Vision》2020年第1期563-570,共8页Luyao Ye Jiangnan He Xinji Zhang Yi Xu Qiuying Chen Yao Yin Ying Fan Lina Lu Jianfeng Zhu Haidong Zou Xun Xu 
This study was funded by the National Natural Science Foundation of China(Grant No.:81670898 and 81703287,Beijing,China);the Shanghai Three-Year Public Health Action Program(Project Nos.GWIV-3.3 and GWIV-13.1,Shanghai,China);the Shanghai High-level Overseas Training Team Program on Eye Public Health(Project No.GWTD2015S08,Shanghai,China);Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support(Project No.20172022,Shanghai,China);Shanghai General Hospital,Clinical Research(Project No.CTCCR-2018Z01,Shanghai,China);the Shanghai Science and Technology Commission Research Project(Project No.17ZR1426900,Shanghai,China);the Shanghai Municipal Planning Commission of Science and Research Fund(Project No.201640090,Shanghai,China);National Key R&D Program of China(Project No.2016YFC0904800,2019YFC0840607);National Science and Technology Major Project of China(Project No.2017ZX09304010);The sponsors or funding organizations had no role in the design or conduct of this research.
Background:To investigate the associations of lens power with age,axial length(AL),and Type 2 diabetes mellitus(DM)in Chinese adults aged 50 and above.Methods:Random clustering sampling was used to identify adults age...
关键词：Lens power Type 2 diabetes mellitus Chinese adults Cross-sectional study 
Microarray-based screening of common pathophysiological processes in dilated cardiomyopathy and ischemic cardiomyopathy
《South China Journal of Cardiology》2019年第3期190-196,200,共8页HE Yong-li LU Jian-jun FENG Zhe WANG Rui HUANG Cheng ZHOU Ying-ling 
supported by National Natural Science Foundation of China(No.81470571,Beijing,China);National Science Foundation for Young Scientists of China(No.81300230,Beijing,China)
Background Heart failure is the end stage of various heart diseases,which has different underlying mechanisms but somehow has similar features among different etiologies. Dilated cardiomyopathy(DCM) and ischemic cardi...
关键词：MICROARRAY BIOINFORMATICS DILATED CARDIOMYOPATHY ISCHEMIC CARDIOMYOPATHY 
Rhabdomyolysis and respiratory insufficiency due to the common ETFDH mutation of c.250G>A in two patients with late-onset multiple acyl-CoA dehydrogenase deficiency被引量：3
《Chinese Medical Journal》2019年第13期1615-1618,共4页Hai-Zhu Chen Ming Jin Nai-Qing Cai Xiao-Dan Lin Xin-Yi Liu Liu-Qing Xu Min-Ting Lin Feng Lin Ning Wang Zhi-Qiang Wang Guo-Rong Xu 
grants from National Natural Science Foundation of China(U1505222,81271254,Beijing).
To the Editor:Late-onset multiple acyl-CoA dehydrogenase deficiency(MADD)is clinically characterized by a fluctuating or progressive proximal myopathy,exercise intolerance but good responsive to riboflavin.ETFDH mutat...
关键词：RHABDOMYOLYSIS respiratory INSUFFICIENCY DOSAGE of INTRAVENOUS 
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