《World Journal of Gastroenterology》

作品数：23523被引量：145314H指数：83
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《World Journal of Gastroenterology》
主办单位：百世登出版集团有限公司
最新期次：2025年16期更多>>
发文主题：HEPATOCELLULAR_CARCINOMAGASTROENTEROLOGYLIVERGASTRIC_CANCERPATIENTS更多>>
发文领域：医药卫生生物学农业科学轻工技术与工程更多>>
发文作者：吴孟超王瑞年林言箴秦兰芳陶厚权更多>>
发文机构：第二军医大学第三军医大学西南医院同济医科大学附属协和医院上海交通大学医学院附属瑞金医院更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>
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Delaying liver aging:Analysis of structural and functional alterations
《World Journal of Gastroenterology》2025年第15期1-7,共7页Yu-Qin Yao Qiong-Yue Cao Zheng Li 
Supported by the National Natural Science Foundation of China,No.82104525;Open Foundation of Key Laboratory of Tropical Plant Resource Chemistry of Hainan Province,No.rdzw2024s01.
This article is based on a recent bibliometric analysis of research progress on liver aging.The liver is notable for its extraordinary ability to rejuvenate,thereby safeguarding and maintaining the organism’s integri...
关键词：Liver aging TELOMERE HEPATOCYTES Caloric restriction Physical exercise REGENERATION 
Management of hepatic encephalopathy following transjugular intrahepatic portosystemic shunts:Current strategies and future directions
《World Journal of Gastroenterology》2025年第15期8-23,共16页Ying Li Yu-Tong Wu Hao Wu 
Supported by the National Natural Science Foundation of China,No.82270649.
Transjugular intrahepatic portosystemic shunts(TIPSs)are generally used for the management of complications of portal hypertension in patients with decompensated cirrhosis.However,hepatic encephalopathy(HE),which impa...
关键词：CIRRHOSIS Portal hypertension Transjugular intrahepatic portosystemic shunt Hepatic encephalopathy Pathophysiological mechanisms Management strategies 
Conversion treatment for advanced intrahepatic cholangiocarcinoma:Opportunities and challenges
《World Journal of Gastroenterology》2025年第15期24-41,共18页Jun-Jie Liu Mi Zhou Tong Yuan Zhi-Yong Huang Zun-Yi Zhang 
The prevalence of intrahepatic cholangiocarcinoma(ICC)is increasing globally.Despite advancements in comprehending this intricate malignancy and formulating novel therapeutic approaches over the past few decades,the p...
关键词：Intrahepatic cholangiocarcinoma Conversion treatment DOWNSTAGING Combination therapy Chemotherapy IMMUNOTHERAPY Locoregional therapies 
Early detection of gastroparesis with diabetic ketoacidosis as initial manifestation:A case-control study
《World Journal of Gastroenterology》2025年第15期42-49,共8页Li Han Qing-Yi Peng Jie Yu Yi-Wen Liu Wei Li Fan Ping Hua-Bing Zhang Yu-Xiu Li Ling-Ling Xu 
Supported by National High Level Hospital Clinical Research Funding,No.2022-PUMCH-B-015;the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences,No.2021-I2M-C&T-B-003.
BACKGROUND Gastroparesis may repeatedly induce diabetic ketoacidosis(DKA),and the differential diagnosis of these diseases is challenging because of similar gastrointestinal symptoms.If DKA is accompanied by gastropar...
关键词：Diabetes mellitus Diabetic ketoacidosis Diabetic gastroparesis Early detection DIAGNOSIS 
Evaluation of scoring systems and hematological parameters in the severity stratification of early-phase acute pancreatitis
《World Journal of Gastroenterology》2025年第15期50-59,共10页Pei-Na Shi Zhang-Zhang Song Xu-Ni He Jie-Ming Hong 
BACKGROUND Acute pancreatitis(AP)is an emergency gastrointestinal disease that requires immediate diagnosis and urgent clinical treatment.An accurate assessment and precise staging of severity are essential in initial...
关键词：Acute pancreatitis Scoring systems Severity stratification Prognostic nutritional index SEVERITY 
Predictive models and clinical manifestations of intrapulmonary vascular dilatation and hepatopulmonary syndrome in patients with cirrhosis:Prospective comparative study
《World Journal of Gastroenterology》2025年第15期60-78,共19页Zhi-Peng Wu Ying-Fei Wang Feng-Wei Shi Wen-Hui Cao Jie Sun Liu Yang Fang-Ping Ding Cai-Xia Hu Wei-Wei Kang Jing Han Rong-Hui Yang Qing-Kun Song Jia-Wei Jin Hong-Bo Shi Ying-Min Ma 
Supported by the National Key Research and Development Program of China,No.2022YFC2305002;Beijing Natural Science Foundation,No.7232079;Middle-aged and Young Talent Incubation Programs(Clinical Research)of Beijing Youan Hospital,No.BJYAYY-YN2022-12,No.BJYAYY-YN2022-13,and No.BJYAYY-YN2022-01;the China Postdoctoral Science Foundation,No.2023M732410 and No.2024T170595.
BACKGROUND Patients with cirrhosis with hepatopulmonary syndrome(HPS)have a poorer prognosis.The disease has a subtle onset,symptoms are easily masked,clinical attention is insufficient,and misdiagnosis rates are high...
关键词：Liver cirrhosis Hepatopulmonary syndrome Prediction model Clinical parameters Biomarkers 
Strain-and sex-dependent variability in hepatic microcirculation and liver function in mice
《World Journal of Gastroenterology》2025年第15期79-95,共17页Bing Wang Yuan Li Qin Ouyang Meng-Ting Xu Ying-Yu Wang Sun-Jing Fu Wei-Qi Liu Xue-Ting Liu Hao Ling Xu Zhang Rui-Juan Xiu Ming-Ming Liu 
Supported by the Beijing Municipal Natural Science Foundation,No.7212068;the National Natural Science Foundation of China,No.81900747.
BACKGROUND The integrity and functionality of the hepatic microcirculation are essential for maintaining liver health,which is influenced by sex and genetic background.Understanding these variations is crucial for add...
关键词：Hepatic microhemodynamics Sex differences Mouse strains Biological oscillators Hepatic microcirculation 
Rhapontin activates nuclear factor erythroid 2-related factor 2 to ameliorate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced gastrointestinal dysfunction in Parkinson's disease mice
《World Journal of Gastroenterology》2025年第15期96-108,共13页Xin-Yu Wang Fang Liu Qi-Tong Wang Shu-Zhu Li Yu-Zhao Ye Tao Chen Ben-Chi Cai 
Supported by the Hainan Provincial Natural Science Foundation of China,No.823MS133 and No.821QN0979。
BACKGROUND Parkinson's disease(PD)-a progressive neurodegenerative disorder-is characterized by motor and gastrointestinal dysfunction.The exploration of novel therapeutic strategies for PD is vital.AIM To investigate...
关键词：Rhapontin Gastrointestinal dysfunction Parkinson’s disease Nuclear factor erythroid 2-related factor 2 Gut-Brain axis Oxidative stress NEUROINFLAMMATION 
Reduced interleukin-2 receptor subunitγexpression in Crohn's disease:A potential mechanism forγδT cell deficiency
《World Journal of Gastroenterology》2025年第13期152-154,共3页Md Sadique Hussain Ajay Singh Bisht Gaurav Gupta 
Crohn’s disease(CD)is a chronic inflammatory disorder characterized by dysregulated immune responses and significant disruption of intestinal immunity.A recent case-control study by Andreu-Ballester et al revealed de...
关键词：Crohn's disease Gastrointestinal immunology Interleukin-2 receptorγsubunit(CD132) Interleukin-7/interleukin-2 signaling pathway Immune regulation Immune signaling T cell apoptosis 
Towards personalized care in minimally invasive esophageal surgery:An adverse events prediction model
《World Journal of Gastroenterology》2025年第13期155-157,共3页Ioannis Karniadakis Alexandra Argyrou Stamatina Vogli Stavros P Papadakos 
This letter addressed the impactful study by Zhong et al,which introduced a risk prediction and stratification model for surgical adverse events following minimally invasive esophagectomy.By identifying key risk facto...
关键词：Minimally invasive esophagectomy Surgical adverse events Risk prediction model Risk stratification HYPOALBUMINEMIA Predictive accuracy Personalized perioperative care Tailored interventions Esophageal surgery 
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