《World Journal of Gastroenterology》

作品数：23456被引量：144930H指数：83
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《World Journal of Gastroenterology》
主办单位：百世登出版集团有限公司
最新期次：2025年11期更多>>
发文主题：HEPATOCELLULAR_CARCINOMAGASTROENTEROLOGYLIVERGASTRIC_CANCERPATIENTS更多>>
发文领域：医药卫生生物学农业科学轻工技术与工程更多>>
发文作者：吴孟超王瑞年林言箴秦兰芳陶厚权更多>>
发文机构：第二军医大学第三军医大学西南医院同济医科大学附属协和医院上海交通大学医学院附属瑞金医院更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>
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Cholangiocarcinoma:The era of liquid biopsy
《World Journal of Gastroenterology》2025年第11期14-32,共19页Evgenia Kotsifa Francesca Saffioti Vasileios K Mavroeidis 
Cholangiocarcinoma(CCA)is a highly aggressive and heterogeneous malignancy arising from the epithelial cells of the biliary tract.The limitations of the current methods in the diagnosis of CCA highlight the urgent nee...
关键词：Biliary tract cancer CHOLANGIOCARCINOMA Circulating tumour cells Cell free DNA Circulating tumour DNA Circulating RNA Biomarkers Extracellular vesicles Precision medicine 
Preoperative prediction of textbook outcome in intrahepatic cholangiocarcinoma by interpretable machine learning: A multicenter cohort study
《World Journal of Gastroenterology》2025年第11期33-45,共13页Ting-Feng Huang Cong Luo Luo-Bin Guo Hong-Zhi Liu Jiang-Tao Li Qi-Zhu Lin Rui-Lin Fan Wei-Ping Zhou Jing-Dong Li Ke-Can Lin Shi-Chuan Tang Yong-Yi Zeng 
Supported by National Key Research and Development Program,No.2022YFC2407304;Major Research Project for Middle-Aged and Young Scientists of Fujian Provincial Health Commission,No.2021ZQNZD013;The National Natural Science Foundation of China,No.62275050;Fujian Province Science and Technology Innovation Joint Fund Project,No.2019Y9108;Major Science and Technology Projects of Fujian Province,No.2021YZ036017.
BACKGROUND To investigate the preoperative factors influencing textbook outcomes(TO)in Intrahepatic cholangiocarcinoma(ICC)patients and evaluate the feasibility of an interpretable machine learning model for preoperat...
关键词：Intrahepatic cholangiocarcinoma Textbook outcome Interpretable machine learning PREDICTION PROGNOSIS 
Construction and validation of machine learning-based predictive model for colorectal polyp recurrence one year after endoscopic mucosal resection
《World Journal of Gastroenterology》2025年第11期46-62,共17页Yi-Heng Shi Jun-Liang Liu Cong-Cong Cheng Wen-Ling Li Han Sun Xi-Liang Zhou Hong Wei Su-Juan Fei 
BACKGROUND Colorectal polyps are precancerous diseases of colorectal cancer.Early detection and resection of colorectal polyps can effectively reduce the mortality of colorectal cancer.Endoscopic mucosal resection(EMR...
关键词：Colorectal polyps Machine learning Predictive model Risk factors SHapley Additive exPlanation 
Development and validation of a predictive model for the pathological upgrading of gastric low-grade intraepithelial neoplasia
《World Journal of Gastroenterology》2025年第11期63-73,共11页Kun-Ming Lyu Qian-Qian Chen Yi-Fan Xu Yao-Qian Yuan Jia-Feng Wang Jun Wan En-Qiang Ling-Hu 
Supported by the National Key Research and Development Program of China,No.2022YFC2503600。
BACKGROUND The discrepancy between endoscopic biopsy pathology and the overall pathology of gastric low-grade intraepithelial neoplasia(LGIN)presents challenges in developing diagnostic and treatment protocols.AIM To ...
关键词：Endoscopic resection Gastric low-grade intraepithelial neoplasia Early gastric cancer Pathological upgrade Prediction model 
Trichostatin A augments cell migration and epithelial-mesenchymal transition in esophageal squamous cell carcinoma through BRD4/c- Myc endoplasmic reticulum-stress pathway
《World Journal of Gastroenterology》2025年第11期164-182,共19页Yan-Min Chen Wen-Qian Yang Ying-Ying Fan Zhi Chen Yu-Zhen Liu Bao-Sheng Zhao 
Supported by the Henan Province Science and Technology Development Plan,No.242102311124;Key Medical Scientific and Technological Project of Henan Province,No.SBGJ202102188;Henan Provincial Medical Science and Technology Project,No.LHGJ20221012;Fundamental Research Funds for the Universities of Henan Province,No.NSFRF240308.
BACKGROUND The causes of death in patients with advanced esophageal cancer are multi-factorial,with tumor metastasis being one of the important factors.Histone acetylation promotes the migration of esophageal squamous...
关键词：Esophageal squamous cell carcinoma Histone deacetylase inhibitor Trichostatin A Endoplasmic reticulum stress Epithelial-mesenchymal transition Cell migration 
Changes in Intestinal flora is associated with chronic diseases
《World Journal of Gastroenterology》2025年第11期183-197,共15页Guo-Heng Jiang Hong-Yu Li Lin-Jun Xie Jing-Yuan Fan Shi-Yi Li Wen-Qian Yu Yi-Ting Xu Meng-Lin He Yi Jiang Xuan Bai Jin Zhou Xin Wang 
Supported by National Natural Science Foundation of China,No.81903398;the Research Start-Up Fund for the Introduction of Talents of Sichuan University,No.YJ2021112;Medical Youth Innovation Research Project of Sichuan Province,No.Q21016;Natural Science Foundation of Sichuan,No.2023NSFSC1927;“From 0 to 1”Innovation Project,Sichuan University,No.2023SCUH0026;Sichuan Provincial Science and Technology Department 2023 Central Guide Local Project,No.2023ZYD0097;Cigar Fermentation Technology Key Laboratory of Tobacco Industry,No.20202309BC530.
BACKGROUND The intestinal flora(IF)has been linked to risks of non-communicable diseases,especially various cancers,stroke,and Alzheimer’s disease.However,many uncertainties of these associations during different sta...
关键词：Intestinal flora Non-communicable diseases Occurrence risk Systematic review META-ANALYSIS 
Roles of autophagy and long non-coding RNAs in gastric cancer
《World Journal of Gastroenterology》2025年第11期198-206,共9页Thang Viet Luong Mai Thi Thu Cao Nam Van Duc Nguyen Hai Nguyen Ngoc Dang Trung Tran Nguyen 
Gastric cancer(GC)is one of the most aggressive malignancies worldwide and is characterized by its poor prognosis and resistance to conventional therapies.Autophagy and long non-coding RNAs(lncRNAs)play critical yet c...
关键词：AUTOPHAGY Gastrointestinal cancer Gastric cancer Long non-coding RNAs Cancer progression EPIGENETIC 
Validity of the efficacy of the spray flushing cleaning method in flexible endoscope reprocessing
《World Journal of Gastroenterology》2025年第11期207-211,共5页Sameera Zeehan Anwardeen Ziaudeen Charleen Shanwen Yeo Danson Xue Wei Yeo 
The advancement in endoscopic technology and techniques has increased its use in the diagnosis and treatment of gastrointestinal diseases.Reprocessing of reusable endoscopes remains a challenge.Inadequate reprocessing...
关键词：Flexible endoscope REPROCESSING Automated spray flushing Sampling Blinding Enzyme detergents Poiseuille’s flow rate COLONOSCOPES 
Improving radiomics-based models for esophagogastric variceal bleeding risk prediction in cirrhotic patients
《World Journal of Gastroenterology》2025年第11期212-215,共4页Arunkumar Krishnan 
A recent study by Peng et al developed a predictive model for first-instance secondary esophageal variceal bleeding in cirrhotic patients by integrating clinical and multi-organ radiomic features.The combined radiomic...
关键词：Artificial intelligence CIRRHOSIS Radiomics Esophagogastric variceal bleeding Esophageal varices BLEEDING 
Impact of poorly controlled type II diabetes mellitus on chemoresistance in colorectal cancer
《World Journal of Gastroenterology》2025年第11期216-221,共6页Aditya Gaur Rick Maity Arkadeep Dhali Jyotirmoy Biswas 
Type 2 diabetes mellitus(T2DM)significantly elevates the risk of colorectal cancer(CRC)and complicates its treatment by promoting chemoresistance.Poor glycemic control has been linked to exacerbated CRC progression an...
关键词：Type 2 diabetes mellitus Colorectal cancer Cancer CHEMORESISTANCE Diabetes mellitus HYPERGLYCEMIA CHEMOTHERAPY 
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