《Journal of Biomedical Research》

作品数：1097被引量：2569H指数：16
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《Journal of Biomedical Research》
主办单位：Nanjing Medical University and Chungbuk National University
最新期次：2025年2期更多>>
发文主题：PATIENTSCASE_REPORTAPOPTOSISMETA-ANALYSISRATS更多>>
发文领域：医药卫生生物学农业科学文化科学更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金中国博士后科学基金更多>>
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Author Correction:circPVT1 promotes silica-induced epithelial-mesenchymal transition by modulating the miR-497-5p/TCF3 axis
《Journal of Biomedical Research》2025年第2期214-214,共1页Siyun Zhou Yan Li Wenqing Sun Dongyu Ma Yi Liu Demin Cheng Guanru Li Chunhui Ni 
Correction to:Journal of Biomedical Research https://doi.org/10.7555/JBR.37.20220249,published on March 28,2024.The authors wish to correct the affiliation of the second author,Yan Li,to the Department of Occupational...
关键词：NANJING affiliated Jiangsu 
The role of perioperative factors in the prognosis of cancer patients:A coin has two sides
《Journal of Biomedical Research》2025年第2期117-127,共11页Yingzhou Tu Sen Wang Haoran Wang Peiyao Zhang Mengyu Wang Cunming Liu Chun Yang Riyue Jiang 
Innovative and Entrepreneurial Team of Jiangsu Province(Grant No.JSSCTD202144);Nanjing Postdoctoral Program(Grant No.BSHNJ2023006);National Natural Science Foundation of China(Grant No.82201380)。
Cancer,potentially the second leading cause of mortality globally,poses a significant health challenge.The conventional treatment for solid tumors typically involves surgical intervention,followed by chemotherapy,radi...
关键词：cancer recurrence anesthesia medications anesthetic techniques perioperative period surgery 
Prophylactic cranial irradiation in small cell lung cancer: A review of evidence
《Journal of Biomedical Research》2025年第2期128-131,共4页Femi Williams Adeoye 
Small cell lung cancer(SCLC), which accounts for about one-sixth of all lung cancer cases, is the most aggressive subtype, with a high propensity for brain involvement[1]. The role of prophylactic cranial irradiation(...
关键词：LUNG CANCER INVOLVEMENT 
Oxytocin ameliorates cognitive impairments by attenuating excitation/inhibition imbalance of neurotransmitters acting on parvalbumin interneurons in a mouse model of sepsisassociated encephalopathy
《Journal of Biomedical Research》2025年第2期132-145,共14页Renqi Li Qiuting Zeng Muhuo Ji Yue Zhang Mingjie Mao Shanwu Feng Manlin Duan Zhiqiang Zhou 
supported by grants from the general project of Nanjing Medical University Science and Technology Development Foundation (Grant No.NMUB20210112)。
Inflammation plays a crucial role in the initiation and progression of sepsis and induces alterations in brain neurotransmission, thereby contributing to the development of sepsis-associated encephalopathy(SAE).Parval...
关键词：excitation/inhibition balance OXYTOCIN cognitive sepsis-associated encephalopathy 
Buccal DNA global methylation and cognitive performance in stunted children under five years of age
《Journal of Biomedical Research》2025年第2期146-154,共9页Ahmad Rusdan Handoyo Utomo Yusnita Yusnita Siti Maulidya Sari Octaviani Indrasari Ranakusuma Sunu Bagaskara Wening Sari Yulia Suciati Anggi Puspa Nur Hidayati Silviatun Nihayah Catur Anggono Putro Neni Nurainy 
Ministry of Education,Culture,Research,and Technology of the Republic of Indonesia through the Kedaireka 2022 Matching Fund Programme(Grant No.282/E1/KS.060.02/2022)。
The prevalence of stunting in Indonesian children under five years of age is approximately 20%.Chronic maternal malnutrition contributes to the risk of stunting by affecting global DNA methylation.In the present study...
关键词：global DNA methylation 5mC ELISA STUNTING COGNITIVE 
Expression profiling and bioinformatics analysis of serum exosomal circular RNAs in lymph node metastasis of papillary thyroid carcinoma
《Journal of Biomedical Research》2025年第2期155-170,I0001-I0004,共20页Huiyong Peng Zhangwei Zhu Jie Xing Qian Xu Changfeng Man Shengjun Wang Yingzhao Liu Zhengdong Zhang 
National Natural Science Foundation of China (Grant No. 81800698);Jiangsu Provincial Medical Key Discipline Cultivation Unit (Grant No. JSDW202241);Research Project of Jiangsu Commission of Health (Grant No. H2023053);Zhenjiang Science and the Technology Planning Project (Grant Nos. SH2023006and SH2023008)。
Most papillary thyroid carcinoma(PTC) patients have a good prognosis. However, lymph node metastasis(LNM), the most common manifestation of disease progression, is frequently associated with a poor prognosis.Neverthel...
关键词：papillary thyroid carcinoma EXOSOME circular RNA regulatory network lymph node metastasis 
miR-19a-3p enhances TGF-β1-induced cardiac fibroblast activation via targeting BAMBI
《Journal of Biomedical Research》2025年第2期171-183,共13页Pengxi Shi Ao Tan Yuanyuan Ma Lingli Que Chuanfu Li Yongfeng Shao Haoliang Sun Yuehua Li Jiantao Li 
National Natural Science Foundation of China (Grant Nos. 82070234 and 82100254)。
Myocardial fibrosis is a major pathogenic factor contributing to cardiac remodeling and heart failure. Recent research has indicated that micro RNAs play a crucial role in the progression of cardiac fibrosis. Bone mor...
关键词：miR-19a-3p BAMBI TGF-Β1 SMAD2/3 myocardial fibrosis 
PAK2 promotes proliferation,migration,and invasion of lung squamous cell carcinoma through the LIMK1/cofilin signaling pathway
《Journal of Biomedical Research》2025年第2期184-197,I0007-I0012,共20页Congcong Wang Junyan Wang Ruifeng Xu Qiushuang Li Xia Huang Chenxi Zhang Baiyin Yuan 
National Natural Science Foundation of China(Grant No.32300615);Nanjing Medical Science and Technique Development Foundation(Grant No.JQX19010)。
Although p21-activated kinase 2(PAK2)is an essential serine/threonine protein kinase,its role in the progression of lung squamous cell carcinoma(LUSC)has yet to be fully understood.We analyzed PAK2 mRNA levels,DNA cop...
关键词：PAK2 lung squamous cell carcinoma LIMK1 COFILIN 
The role of SRPK1-mediated phosphorylation of SR proteins in the chromatin configuration transition of mouse germinal vesicle oocytes
《Journal of Biomedical Research》2025年第2期198-208,I0013-I0015,共14页Xia Wang Shuai Zhou Haojie Yin Jian Han Yue Hu Siqi Wang Congjing Wang Jie Huang Junqiang Zhang Xiufeng Ling Ran Huo 
National Natural Science Foundation of China(Grant Nos.32070838 and 82301874);Open Fund of State Key Laboratory of Reproductive Medicine,Nanjing Medical University(Grant No.SKLRM K202102)。
Meiotic resumption in mammalian oocytes involves nuclear and organelle structural changes,notably the chromatin configuration transition from a non-surrounding nucleolus(NSN)to surrounding nucleolus(SN)in germinal ves...
关键词：OOCYTE CHROMATIN nuclear speckle SR protein PHOSPHORYLATION SRPK1 
Extinction of influenza B Yamagata:Its impact on public health and vaccine implications
《Journal of Biomedical Research》2025年第2期209-212,共4页Muhammad Awais Ashraf Muhammad Asif Raza Muhammad Nabeel Amjad 
Dear Editor,The circulation of respiratory viruses,primarily the influenza virus,has been disrupted by the emergence of the COVID-19 pandemic and SARS-CoV-2.Epidemiological surveillance data during the COVID-19 pandem...
关键词：INFLUENZA EPIDEMIOLOGY RESPIRATORY 
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