《Bio-Design and Manufacturing》

作品数：330被引量：391H指数：9
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《Bio-Design and Manufacturing》
主办单位：浙江大学;浙江大学出版社；Springer
最新期次：2025年2期更多>>
发文主题：BIOPRINTINGPRINTINGTISSUE_ENGINEERINGHYDROGELSCAFFOLD更多>>
发文领域：医药卫生自动化与计算机技术生物学一般工业技术更多>>
发文基金：国家自然科学基金中国博士后科学基金高等学校学科创新引智计划国家重点基础研究发展计划更多>>
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3D printing for tissue/organ regeneration in China
《Bio-Design and Manufacturing》2025年第2期169-242,I0001,I0002,共76页Chaofan He Jiankang He Chengtie Wu Changshun Ruan Qi Gu Yongqiang Hao Yang Wu Shuo Bai Xiaoxiao Han Liliang Ouyang Jun Yin Hongzhao Zhou Zhuo Xiong Maobin Xie Lei Shao Jing Nie Liang Ma Cijun Shuai Changchun Zhou Xin Zhao Xuetao Shi Mengfei Yu Jiayin Fu Peng Wen Huixia Xuan Yuan Pang Yan’en Wang Yuan Sun Ziqi Gao Abdellah Aazmi Jingbo Zhang Tianhong Qiao Qixiang Yang Ke Yao Mao Mao Jianxin Hao Pinpin Wang Jirong Yang Huawei Qu Xinhuan Wang Xin Liu Shen Ji Shasha Liu Jingke Fu Bingxian Lu Mohan Wu Feng Chen Zihao Zheng Boqing Zhang Muyuan Chai Chaoying Zhang Mouyuan Sun Bo Peng Huayong Yang Yong He 
supported by the National Natural Science Foundation of China(Nos.52325504,52235007,and T2121004).
As surgical procedures transition from conventional resection to advanced tissue-regeneration technologies,human disease therapy has witnessed a great leap forward.In particular,three-dimensional(3D)bioprinting stands...
关键词：3D printing BIOPRINTING Tissue engineering Regenerative medicine 
Microneedles for non-transdermal drug delivery:design strategies and current applications
《Bio-Design and Manufacturing》2025年第2期243-274,I0003,共33页Jinhong Xu Xiangyi Liao Danli Chen Xiuzhuo Jia Xufeng Niu 
financial support from the Beijing Natural Science Foundation(No.L234020);the National Natural Science Foundation of China(Nos.12472325 and 12272032);the 111 Project(No.B13003).
Microneedles(MNs)are an innovative and viable option for drug delivery that offer the distinct advantages of minimal invasiveness,painlessness,stable drug loading,efficient drug permeation,and biocompatibility.MNs wer...
关键词：Microneedles(MNs) Biocompatible materials Non-transdermal drug delivery Controlled release 
A design strategy for long-term stability of porous PEEK implants by regulation of porous structure and in vivo mechanical stimulation
《Bio-Design and Manufacturing》2025年第2期275-287,I0004,共14页Yingjie Liu Ling Wang Jie Zhang Shuguang Liu Jibao Zheng Jianfeng Kang Enchun Dong Changning Sun Ruhan A Chaozong Liu Chuncheng Yang Dichen Li 
supported by the National Key R&D Program of China(No.2023YFB4603500);the Program for Innovation Team of Shaanxi Province(No.2023-CX-TD-17);the Fundamental Research Funds for the Central Universities;the Shaanxi Province Qinchuangyuan“Scientist+Engineer”Team Construction Project(No.2022KXJ-106).
The bioinert nature of polyether ether ketone(PEEK)material limits the widespread clinical application of PEEK implants.Although the porous structure is considered to improve osseointegration of PEEK implants,it is ha...
关键词：Porous polyether ether ketone(PEEK)implant OSTEOINTEGRATION Interface biomechanics Maxillofacial implants Finite element analyses Fused filament fabrication(FFF)3D printing 
Hydroxy-α-sanshool-loaded adipose-targeted mesoporous silica nanoparticles induce white adipose browning and reduce obesity by activating TRPV1
《Bio-Design and Manufacturing》2025年第2期288-309,I0005-I0011,共29页Qing Zhang Chengxun He Juan Guo Dandan Tang Die Qian Chuan Zheng Chunjie Wu Wei Peng 
supported by the Natural Science Foundation of Sichuan Province(No.2022NSFSC0720);Research Center for the Development of the Comprehensive Health Industry and Rural Revitalization of Sichuan TCM(No.DJKYB202306);State Administration of Traditional Chinese Medicine of Sichuan Province of China(No.2020HJZX001).
Obesity has become a global threat to health;however,the available drugs for treating obesity are limited.We investigated the anti-obesity effect of hydroxy-α-sanshool(HAS),an amide derived from the fruit of Zanthoxy...
关键词：Hydroxy-α-sanshool Adipocyte targetability Mesoporous silica nanoparticles White adipose tissue browning OBESITY 
Development of a multifunctional uniaxial bioreactor with real-time monitoring of culture conditions and tissue health
《Bio-Design and Manufacturing》2025年第2期310-330,I0012-I0015,共25页Adit Mehta Po-Feng Lee Eric Renteria Frank C.Marini Ji Hyun Kim Tracy Criswell Thomas D.Shupe Anthony Atala Metin N.Gurcan Shay Soker Joshua Hunsberger James J.Yoo Young Min Ju 
possible by the US Army Medical Research and Development Command through the Medical Technology Enterprise Consortium under Contract#W81XWH-15-9-0001.
Bioreactors are used to dynamically condition engineered tissues to achieve the required degree of maturation before in vivo implantation.Integrating sensors and imaging capabilities into bioreactors can help us under...
关键词：BIOREACTOR Manufacturing Monitoring sensors and automation Regenerative medicine Tissue engineering 
Optimization-based conformal path planning for in situ bioprinting during complex skin defect repair
《Bio-Design and Manufacturing》2025年第1期1-19,I0001,共20页Wenxiang Zhao Chuxiong Hu Yunan Wang Shize Lin Ze Wang Tao Xu 
supported in part by the National Natural Science Foundation of China(Nos.52205532 and 624B2077);the National Key Research and Development Program of China(No.2023YFB4302003).
The global demand for effective skin injury treatments has prompted the exploration of tissue engineering solutions.While three-dimensional(3D)bioprinting has shown promise,challenges persist with respect to achieving...
关键词：In situ bioprinting Path planning Robot control Skin injury repair 
Deep phenotyping of testosterone-prompted fibrosis in arrhythmogenic right ventricular cardiomyopathy using iPSC-derived engineered cardiac spheroids
《Bio-Design and Manufacturing》2025年第1期20-35,I0002-I0012,共27页Hongyi Cheng Xinrui Wang Sichong Qian Yike Zhang Jincheng Jiao Bingyu Zheng Yue Zhu Hua Xu Jia Song Feng Zhang Xiaohong Jiang Chang Cui Minglong Chen 
supported by the National Natural Science Foundation of China(Nos.82370322 to CC,82200352 to FZ,82300352 to YZ,22275034 to HX,and 82070343 to MLC);the Natural Science Foundation of Jiangsu Province of China(Nos.BK20220710 to FZ and BK20230733 to YZ);Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.JX13414086 to HYC).
Arrhythmogenic right ventricular cardiomyopathy(ARVC)is a progressive disease characterized by adipose and fibrous replacement of the myocardium.While elevated testosterone levels have been implicated in the pathologi...
关键词：Arrhythmogenic right ventricular cardiomyopathy(ARVC) Gender difference Cardiac spheroids Testoste-rone FIBROSIS 
Enhancing angiogenesis and osseointegration through a double gyroid Ti6Al4V scaffold with triply periodic minimal surface
《Bio-Design and Manufacturing》2025年第1期36-54,I0013-I0017,共24页Hao Liu Hao Chen Bin Sun Danyang Fan Aobo Zhang Hanqiang Liu Hexiang Wei Wenbo Yang Yongyue Li Peng Xia Qing Han Jincheng Wang 
supported bythe National Natural Science Foundation of China(Nos.U23A20523,82272504,and 82072456);the Department of Science and Technology of Jilin Province,China(Nos.20210101439JC,20210101321JC,20220204119YY,202201ZYTS131,202201ZYTS129,20230204114YY,YDZJ202201ZYTS505,and YDZJ202301ZYTS076);the Special Program for Science and Technology Personnel of Changchun(No.ZKICKJJ2023015);the Key Training Plan for Outstanding Youth of Jilin University(No.419070623036);the Research Fund of the First Hospital of Jilin University(No.2021-zl-01);the Graduate Innovation Fund of Jilin University(No.2024CX125);the Foun-dation of National Center for Translational Medicine(Shanghai)SHU Branch,China(No.SUITM-202405).
The pore structure of porous scaffolds plays a crucial role in bone repair.The prevalent bone implant structure in clinical practice is the traditional cubic structure.However,the traditional cubic structure exhibits ...
关键词：Double gyroid Triply periodic minimal surface OSSEOINTEGRATION ANGIOGENESIS 
4D-printed snake-like biomimetic soft robots
《Bio-Design and Manufacturing》2025年第1期55-67,I0018-I0038,共34页Xingcheng Ou Jiaqi Huang Dantong Huang Xiaohong Li Guoliang Chen Yabin Yang Ran Bi Yu Sheng Shuang-Zhuang Guo 
the National Natural Science Foundation of China(Nos.52105421 and 52373050);the Guangdong Provincial Natural Science Foundation,China(No.2022A1515011621);the Science and Technology Projects in Guangzhou,China(Nos.202102080330 and 2024A04J6446);the Fundamental Research Funds for the Central Universities,Sun Yat-sen University(No.22qntd0101).
Wireless millirobots engineered to infiltrate intricate vascular networks within living organisms,particularly within constricted and confined spaces,hold immense promise for the future of medical treatments.However,w...
关键词：4D printing Magnetic-responsive ink Untethered medical soft robot Snake-like robot Drug delivery 
3D bioprinting of a dermal scaffold for full-thickness skin tissue regeneration
《Bio-Design and Manufacturing》2025年第1期68-84,I0039-I0041,共20页Lu Han Zixian Liu Meng Li Zhizhong Shen Jianming Wang Shengbo Sang 
supported by the National Natural Science Foundation of China(Nos.51975400 and 62031022);the Shanxi Provincial Key Medical Scientific Research Project(No.2020XM06);the Shanxi Provincial Basic Research Project(Nos.202103021221006,20210302123040,and 202103021223069);the Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi(No.2021L044);the Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering(No.2022SX-TD026).
Dermal substitutes have provided a template for the regeneration and reconstruction of the dermis.However,the healed skin tissue often exhibits abnormal morphology and functionality,including scarring and inflammation...
关键词：3D printing Dermal scaffold PHOTO-CROSS-LINKING Skin tissue regeneration 
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