《Hepatoma Research》

作品数:463被引量:267H指数:5
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《Hepatoma Research》
主办单位:OAE出版公司
最新期次:2023年1期更多>>
发文主题:HEPATOCELLULAR_CARCINOMAHEPATOCELLULARINSTRUCTIONSAUTHORLIVER更多>>
发文领域:医药卫生文化科学自动化与计算机技术理学更多>>
发文基金:国家自然科学基金国家重点基础研究发展计划广西壮族自治区自然科学基金World Health Organization更多>>
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Insights on liver transplantation and multimodal treatment for intrahepatic cholangiocarcinoma
《Hepatoma Research》2023年第1期195-200,共6页Shankar Logarajah John Nida Eve Simoneau Lavanya Yohanathan 
The treatment of intrahepatic cholangiocarcinoma(iCCA)has traditionally been limited to surgical resection or systemic therapy.The role of liver transplantation in the management of iCCA is a topic currently being exp...
关键词:Intrahepatic cholangiocarcinoma liver transplantation transplant oncology 
Liver transplantation for intrahepatic cholangiocarcinoma:a narrative review of the latest advances
《Hepatoma Research》2023年第1期201-211,共11页Francisco Calderon Novoa Victoria Ardiles Juan Pekolj Juan Mattera Martin de Santibañes 
Intrahepatic cholangiocarcinoma(iCCA)is a rare tumor that arises from second order or smaller bile ducts.Its incidence has been growing in the last couple of decades,in parallel with its mortality rates,both in Americ...
关键词:Intrahepatic cholangiocarcinoma LT ICCA 
Genomic alterations in intrahepatic cholangiocarcinoma
《Hepatoma Research》2023年第1期212-236,共25页Sara E.Young Ramja Sritharan Daniela Sia 
DS is supported by the Tisch Cancer Institute(Icahn School of Medicine at Mount Sinai),the F.Klion Award,i3 Genesis Award and the TCI Dev.Funds Award 2023.
Intrahepatic cholangiocarcinoma(iCCA)is an aggressive and heterogeneous biliary cancer with a poor prognosis and limited treatment options.The molecular pathogenesis of iCCA involves a highly complex process entailing...
关键词:CHOLANGIOCARCINOMA ICCA CANCER genetic alterations targeted therapy precision medicine 
Tumor microenvironment highlighting tumor-associated macrophages and immune cells
《Hepatoma Research》2023年第1期237-257,共21页Giulio Lodetti Zangrandi Dilruba Tirpanlar Mirella Pastore Cristiana Soldani Ana Lleo Chiara Raggi 
Cholangiocarcinoma(CCA)grows within a highly desmoplastic microenvironment,exhibiting a continuous interconnection with the immune infiltrate,which is characterized by an abundance of immune cells,including natural ki...
关键词:Cholangiocarcinoma(CCA) immune infiltrate tumor-associated macrophages(TAMs) MACROPHAGE macrophage polarization tumor microenvironment 
Neoadjuvant chemotherapy alone or combined with trans-arterial therapies for downstaging unresectable intrahepatic cholangiocarcinoma to surgical resection: a narrative review
《Hepatoma Research》2023年第1期258-266,共9页Francesca Caputo Matteo Serenari Andrea Palloni Matteo Ravaioli Giovanni Brandi Matteo Cescon 
Intrahepatic cholangiocarcinoma(ICCA)incidence has been rising in the last few decades.Currently,hepatic resection is the only curative treatment for ICCA,and there is a lack of evidence supporting the use of preopera...
关键词:CHOLANGIOCARCINOMA chemotherapy LOCOREGIONAL 
Cholangiocarcinoma tumor microenvironment highlighting fibrosis and matrix components
《Hepatoma Research》2023年第1期267-288,共22页Alessandra Caligiuri Maurizio Parola Fabio Marra Stefania Cannito Alessandra Gentilini 
Cholangiocarcinoma(CCA)is an extremely aggressive malignancy characterized by a very limited prognosis and scarce treatment options.The majority of patients are diagnosed at an advanced stage and do not qualify for po...
关键词:Tumor microenvironments CAFs TAMS CCA tumor-reactive stroma therapeutic target INTRODUCTION 
The future direction of liver transplantation for intrahepatic cholangiocarcinoma
《Hepatoma Research》2023年第1期289-297,共9页Miho Akabane Yuki Imaoka Kazunari Sasaki 
Liver transplantation has emerged as a potential therapeutic option for select patients with intrahepatic cholangiocarcinoma(iCCA)who are not amenable to curative resection.Recent studies have challenged the tradition...
关键词:Intrahepatic cholangiocarcinoma(ICCA) liver transplantation CIRRHOSIS liver resection PROGNOSIS 
Ultrasonography in surveillance for hepatocellular carcinoma in patients with non-alcoholic fatty liver disease被引量:1
《Hepatoma Research》2023年第1期478-494,共17页Theresa J.Hydes Daniel J.Cuthbertson Daniel H.Palmer Omar Elshaarawy Philip J.Johnson Rashika Fernando Timothy J.Cross 
International guidelines recommend six monthly ultrasounds as the primary surveillance tool for patients at risk of hepatocellular carcinoma(HCC).The dominant driver of liver disease in HCC surveillance populations is...
关键词:Non-alcoholic fatty liver disease hepatocellular carcinoma ultrasound scan STEATOSIS OBESITY 
Challenges and barriers in hepatocellular carcinoma(HCC)surveillance for patients with non-alcoholic fatty liver disease(NAFLD)被引量:2
《Hepatoma Research》2023年第1期495-502,共8页Kara Wegermann Anna Mae Diehl Cynthia A.Moylan 
The proportion of hepatocellular carcinoma(HCC)cases due to NAFLD is expected to increase,paralleling the rise in NAFLD due to the obesity epidemic.Early detection is critical,as it potentially enables curative treatm...
关键词:NAFLD HCC non-invasive biomarker radiomics 
The role of tumor microenvironment in cholangiocarcinoma
《Hepatoma Research》2023年第1期503-517,共15页Maria Eva Argenziano Michele Montori Chiara Scorzoni Antonio Benedetti Marco Marzioni Luca Maroni 
Cholangiocarcinoma(CCA)is an extremely aggressive neoplasia,mostly because of diagnostic delay and lack of effective therapies.CCA is typically surrounded by a peculiar microenvironment that includes abundant desmopla...
关键词:Tumor microenvironments CHOLANGIOCARCINOMA cancer-associated fibroblast tumorassociated macrophages myeloid-derived suppressor cells Tumor-infiltrating lymphocytes dendritic cells IMMUNOTHERAPY 
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