Connective tissue is a dynamic structure that reacts to environmental cues to maintain homeostasis,including mechanical properties.Mechanical load influences extracellular matrix(ECM)—cell interactions and modulates ...
This research was carried out within the State Assignment of the Ministry of Science and Higher Education of the Russian Federation(project FZGW-2024-0003).
Objective:The objective of this study was to determine the level of methotrexate(MTX)toxicity in the intestines of mice and to evaluate the protective effect of probiotics composed of Streptococcus,Bifidobacterium,and...
supported by the Natural Science Foundation of Hunan Province(Grant Nos.2021JJ30050 and 2023JJ50368);Science and Technology Program of Hunan Province(Grant No.2021SK50313);the Research Project of Hunan Provincial Health Commission(Grant Nos.202203102912 and 202203103105,W20243264);the Science and Technology Program of Chenzhou(Grant No.ZDYF2020011);the Key Project of the First People’s Hospital of Chenzhou(Grant No.CZYY202203);the Innovative Team Project of the First People’s Hospital of Chenzhou(Grant No.CX202103).
Nucleic acid analysis is a key technique that enables accurate detection of various microorganisms.Conventional nucleic acid testing typically requires access to specialized laboratories,equipment,and trained personne...
supported by 1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University(No.ZYGD23030);National Natural Science Foundation of China(No.82172254);Science and Technological Supports Project of Sichuan Province,China(No.2024YFFK0214).
With organ transplantation facing many dilemmas,tissue and organ regeneration as an alternative has bright prospects.In regenerative medicine,Three-dimensional(3D)printing technology and stem cells has been widely app...
supported by Guangxi Natural Science Foundation(2023GXNSFAA026128).
The role and regulatory mechanisms of macrophage polarization in cardiac transplantation have gained significant attention.Macrophages can polarize into either the M1(pro-inflammatory)or M2(anti-inflammatory)phenotype...
supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF)and funded by the Ministry of Education(2021R1I1A3056002,to Jinu Kim,RS-2023-00274853,to Daeun MOON).
The epidermal growth factor receptor(EGFR)is a transmembrane glycoprotein that plays a crucial role in signal transduction and cellular responses.This review explores the function of EGFR in kidney physiology and its ...
supported in part by the National Natural Science Foundation of China(Nos.32270555 and 32072954).
Hedgehog(HH)signaling has been researched for decades and Hedgehog has 3 homologs:Sonic Hedgehog(Shh),Indian Hedgehog(Ihh),and Desert Hedgehog(Dhh).Dhh is the one involved in male gonad and germ cell development.The d...
Anderson Nogueira Mendes(#302704/2023-0)is grateful to the public Brazilian agency“Conselho Nacional de Desenvolvimento Científico e Tecnológico”(CNPq)for their personal scholarships.
Neurodegenerative diseases are a major public health challenge,mainly affecting the elderly population and compromising their cognitive,sensory,and motor functions.Currently,available therapies focus on alleviating sy...
The COVID-19 pandemic,caused by the newly emerged coronavirus SARS-CoV-2,has resulted in unprecedented global health challenges,including millions of infections and deaths.While the direct effects of the virus are cri...
Pediatric inflammatory bowel disease(IBD)is a chronic and heterogeneous disease.IBD is commonly classified into Crohn’s disease and ulcerative colitis.It is linked to serious symptoms and complications.The onset of I...