《Biosafety and Health》

作品数:281被引量:341H指数:7
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《Biosafety and Health》
主办单位:中华医学会
最新期次:2024年6期更多>>
发文主题:SARS-COVBIOSAFETYVIRUSINFECTIONBIO更多>>
发文领域:医药卫生农业科学生物学经济管理更多>>
发文基金:国家自然科学基金北京市自然科学基金国家重点基础研究发展计划上海市自然科学基金更多>>
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Antigenicity and genetic properties of an Eurasian avian-like H1N1 swine influenza virus in Jiangsu Province,China
《Biosafety and Health》2024年第6期319-326,共8页Fang He Huiyan Yu Liqi Liu Xiyan Li Yadong Xing Lei Yang Pengfei Yang Liguo Zhu Zi Li 
supported by the National Key Research and Development Program of China(Grant number 2023YFC2606500);Huai'an City Innovation Service Capacity Building Program(Key Laboratory Construction)(Grant number HAP201906);Jiangsu Province 333 Project.
Pigs are vital genetic mixing vessels for human and avian influenza viruses because their tracheal epitheliums possess both sialic acidα-2,6-Gal andα-2,3-Gal receptors.Cross-species transmission of influenza A virus...
关键词:Eurasian avian-like H1N1 swine influenza virus(EAH1N1 SIVs) Amino-acid sites ANTIGENICITY Drug resistance 
Rapidly quantification of intact infectious H1N1 virus using ICA-qPCR and PMA-qPCR
《Biosafety and Health》2024年第6期327-336,共10页Chudan Liang Zequn Wang Linjin Fan Yulong Wang Yuandong Zhou Xiaofeng Yang Jingyan Lin Pengfei Ye Wendi Shi Hongxin Huang Huijun Yan Linna Liu Jun Qian 
supported by Key-Area Research and Development Program of Guangdong Province,China(2022B1111010004,2021B1212040017);Basic Research Program of Guangzhou Municipal Science and Technology Bureau(SL2023A03J01074);Guangdong Provincial Highly Pathogenic Microorganism Science Data Center(2024B1212070013);Shenzhen Science and Technology Program(ZDSYS20230626091203007).
The increase in emerging and reemerging infectious diseases has underscored the need for the prompt monitoring of intact infectious viruses and the quick assessment of their infectivity.However,molecular techniques ca...
关键词:Intact infectious virus Rapid quantification Integrated cell absorption quantitative polymerase chain reaction(ICA-qPCR) Propidium monoazide quantitative polymerase chain reaction(PMA-qPCR) INACTIVATION 
Q fever diagnosed using metagenomic next-generation sequencing in Guangdong Province,China
《Biosafety and Health》2024年第6期337-340,共4页Ting Hu Yuan Cheng Jia Wan Yandong Liu Yali Zhuang Mengxi Zhou Xin Zhang Xiaohua Tan Aiping Deng Meng Zhang Peng Wang Xiaoying Li Jun Zong Lihong Cheng Min Kang 
supported by The Key-Area Research and Development Program of Guangdong Province (2022B1111020006);The Medical Scientific Research Foundation of Guangdong Province, China, 2024 (A2024600). We thank all the participants in the study.
Q fever is a zoonotic disease caused by infection withCoxiella burnetii(C.burnetii).Due to its atypical symptoms and the absence of specific detection methods,Q fever is underdiagnosed commonly.Herein,we report a case...
关键词:Q fever Coxiella burnetii(C.burnetii) Zoonotic disease 
Narciclasine inhibits vaccinia virus infection by activating the RhoA signaling pathway
《Biosafety and Health》2024年第6期341-349,共9页Ting Xu Zhengyang Pan Xue Li Mengyang Zhao Zichen Li Leiliang Zhang 
supported by the National Natural Science Foundation of China(82272306 and 82072270);Shandong Provincial Natural Science Foundation(ZR2024MH017);Taishan Scholars Program(tstp20221142).
In 2022,a sharp rise in global cases of mpox virus(MPXV)led the World Health Organization(WHO)to declare it a public health emergency of international concern.However,progress in developing drugs targeting MPXV has be...
关键词:Mpox virus(MPXV) Vaccinia virus(VACA) NARCICLASINE RHOA Extracellular enveloped virus(EEV) 
Rapid generation and characterization of recombinant HCoV-OC43-VR1558 infectious clones expressing reporter Renilla luciferase
《Biosafety and Health》2024年第6期350-360,共11页Fei Ye Na Wang Qiongge Guan Mengwei Wang Jiewei Sun Desheng Zhai Baoying Huang Ying Zhao Wenjie Tan 
supported by the National Key Research and Development Program of China(2022YFC2304100 and 2021YFA1201003).
Viral infectious clones(ICs)serve as robust platforms for studying viral biology and screening antiviral agents using reverse genetics.However,the molecular profiles and complex limitations of human coronaviruses(HCoV...
关键词:Infectious clones Human coronaviruses(HCoV)-OC43 Transformation-associated recombination(TAR) Reporter Renilla luciferase(Rluc) 
Molecular epidemiological study on tick-borne pathogens in Qinghai Province,Northwestern China
《Biosafety and Health》2024年第6期361-368,共8页Chunfeng Luo Yonghong Song Luoyuan Xia Minxuan Liu Hao Feng Licheng Xiao Ming Xu Xiangyin Cai Jianye Cui Rong Xiang Jihu Yang Wei Kan Yanli Shen Yuanlian Ma Zhanhao Zeng Baohan Liu Yulian Tao Huimin Yu Yi Sun Xiaorun Wang Jiafu Jiang 
funded by the National Natural Science Foundation of China(U2002219);The datasets generated or analyzed during the current study are available from the corresponding author on reasonable request;All the nucleotide sequences obtained in this study are available in the GenBank of National Center for Biotechnology Information with accession numbers OR805110-OR805127,OR792783-OR792797,OR793990-OR793998,and OR813910-OR813915.
Recently,there has been a continuous stream of reports on emerging tick-borne pathogens affecting humans.Qinghai Province,located in the northweastern region,is one of China’s major pastoral areas,providing a suitabl...
关键词:TICK Tick-borne pathogens CO-INFECTION Distribution of Qinghai Province 
A comparative analysis of influenza and COVID-19:Environmental-ecological impacts,socioeconomic implications,and future challenges
《Biosafety and Health》2024年第6期369-375,共7页Yongman Guo Kuiying Gu Paul A.Garber Ruiling Zhang Zijian Zhao Lei Xu 
In the last century,global pandemics have been primarily driven by respiratory infections,which consistently rank among the top 20 causes of death worldwide.The coronavirus disease 2019(COVID-19)pandemic has underscor...
关键词:INFLUENZA Coronavirus disease 2019(COVID-19) Epidemiological characteristics Influencing factors Public health challenges 
Towards the first synthetic eukaryotic cell
《Biosafety and Health》2024年第6期376-382,共7页Wangyue Xu Yue Teng Sijie Zhou 
supported by the National Key Research and Development Program of China(2023YFA0913700);China Postdoctoral Science Foundation(2023 M732591);the Key R&D Program of Shandong Province,China(2022SFGC0102).
With the rapid advance in synthetic biology and the expanding field of synthetic genomics,the realization of a redesigned yeast genome has become an achievable milestone.Multiple eukaryotic chromosomes,meticulously de...
关键词:Synthetic biology Synthetic genomics EUKARYOTES 
Developing an advanced course of vaccinology in middle-income countries:The case of China
《Biosafety and Health》2024年第5期257-259,共3页Likui Wang Lei Guo Yunguo Liu Anna Du Shuo Zhao George F.Gao 
supported by the University of Chinese Academy of Sciences Education Foundation and the Bill&Melinda Gates Foundation(INV-008950)。
1.Introduction.The Immunization Agenda 2030 outlined the importance of capacity building for researchers,regulators and public health officials at national,regional and local levels in its multiple strategic prioritie...
关键词:INCOME FRONTIER STRATEGIC 
Advances and challenges of mpox detection technology
《Biosafety and Health》2024年第5期260-269,共10页Wenjing Liu Erxin Zhang Wei Li Ruichen Lv Yanfeng Lin Yingjia Xu Jiameng Li Yuzhen Lai Yuxin Jiang Sijia Lin Xueqin Wang Peize Zhou Yue Song Wanpeng Shen Yiqian Sun Yuexi Li 
financial support was received for the research,authorship,and/or publication of this article;funded by Nanjing Bioengineering(Gene)Technology Center for Medicines(2024YQFH01)。
Mpox is a zoonotic disease caused by the monkeypox virus(MPxV).Diagnosing and treating the disease has become a global health concern requiring close attention to its spread to non-endemic regions.Clinical diag-nosis ...
关键词:Monkeypox virus(MPXV) Detection technology Point-of-care testing(POCT) BIOSENSOR 
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