AMYLOIDS

作品数：7被引量：2H指数：1
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相关领域：医药卫生更多>>
相关机构：上海交通大学清华大学更多>>
相关期刊：《Frontiers of Chemical Science and Engineering》《Aging Communications》《Food Materials Research》《Neural Regeneration Research》更多>>
相关基金：国家自然科学基金更多>>
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Beyond neurodegeneration:engineering amyloids for biocatalysis
《Neural Regeneration Research》2025年第10期2915-2916,共2页Andrea Bartolomé-Nafría Javier García-Pardo Salvador Ventura 
Amyloid fibrils are highly organized protein or peptide aggregates,often characterized by a distinctive supramolecular cross-β-sheet structure.The formation and accumulation of these structures have been traditionall...
关键词：structure AMYLOID 
1,3,4-oxadiazole-a bioactive scaffold for treating major depression-associated cognitive dysfunction
《Aging Communications》2023年第2期26-34,共9页Davinder Kumar Virender Kumar Aakash Deep Harsh Kumar Rakesh Kumar Marwaha 
Background:Alzheimer’s disease affects millions of people worldwide,and one of its major characteristics is the accumulation of extracellular Aβpeptides in the human brain,leading to neuronal death and resulting in ...
关键词：1 3 4-OXADIAZOLE Alzheimer’s disease DEMENTIA AMYLOIDS antioxidant properties 
Interaction between polyphenols and amyloids:from the view of prevention of protein misfolding disorders related diseases
《Food Materials Research》2022年第1期12-26,共15页Chengcheng Ruan Junhao Kong Xiaoqian He Bing Hu Xiaoxiong Zeng 
funded by the National Natural Science Foundation of China (No.31901760,No.31871843);the Natural Science Foundation of Jiangsu Province—Distinguished Youth Foundation (BK20200022);the Natural Science Foundation of Jiangsu Province—Youth Foundation (BK20190530);Jiangsu Agricultural Science and Technology Innovation Fund (CX (21)3040);Laboratory of Lingnan Modern Agriculture Project (NZ2021034);the Fundamental Research Funds for the Central Universities,China (KJJQ202102,KYDZ201903);a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.
Amyloid is the term usually used to describe a particular type of elongated,unbranched protein fibril with cross-β-sheet characteristics,formed through the ordered aggregation of peptides or denatured proteins.Amyloi...
关键词：INTERACTION properties AGGREGATION 
A crate of Pandora:do amyloids from bacteria promote Alzheimer’s disease?
《Neural Regeneration Research》2021年第5期988-989,共2页Vu Thu Thuy Nguyen Kristina Endres 
This work was supported by funding from the MWWK,Germany(research consortium NeuroDegX).
Incidence for microbes as drivers of Alzheimer’s disease(AD)pathology:AD is the predominant neurodegenerative disease within the elderly.Over 50 million patients suffer from dementia currently world-wide and an estim...
关键词：AMYLOID ALZHEIMER PATHOLOGY 
Physical and toxicological profiles of human IAPP amyloids and plaques
《Science Bulletin》2019年第1期26-35,共10页Aleksandr Kakinen Yunxiang Sun Ibrahim Javed Ava Faridi Emily H.Pilkington Pouya Faridi Anthony W.Purcell Ruhong Zhou Feng Ding Sijie Lin Pu Chun Ke Thomas P.Davis 
supported by ARC Project CE140100036 (Davis), NSF CAREER CBET-1553945 (Ding), NIH MIRA R35GM119691 (Ding) and Monash Institute of Pharmaceutical Sciences (Ke); Purcell is supported by a Principal Research Fellowship from the Australian NHMRC;Pilkington acknowledges an Australian Government Research Training Program (RTP) Scholarship;Javed acknowledges Monash International Postgraduate Research Scholarship
Although much has been learned about the fibrillization kinetics, structure and toxicity of amyloid proteins, the properties of amyloid fibrils beyond the saturation phase are often perceived as chemically and biologi...
关键词：IAPP AMYLOID PLAQUE Self assembly Toxicity 
Cystine oligomers successfully attached to peptide cysteine- rich fibrils
《Frontiers of Chemical Science and Engineering》2016年第1期99-102,共4页Christian Bortolini Mingdong Dong 
Amyloid peptides are renowned to be related to neurodegenerative diseases, however, a fruitful avenue is to employ them as high-performance nanomaterials. These materials benefit from the intrinsic outstanding mechani...
关键词：CYSTEINE peptide fibrils gold nanoparticles AMYLOIDS OLIGOMERS nanomaterials 
Secondary structural formation of alpha-synuclein amyloids as revealed by g-factor of solid-state circular dichroism.被引量：2
《中国生物学文摘》2006年第9期30-30,共1页Lin XJ Zhang F Xie YY Bao WJ He JH Hu HY 
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